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The Big & Dandy 6-APB Thread (Part 5)

THCified said:
Thing is, i did the 6APB today the 2nd time ever (first time @60mgs just gave me headache; it's almost a year ago) and it was ok, like above said, i was more social/chatty (after the somewhat strange come-up), grinding my teeth etc., even my pupils are dilated like i haven't seen them years, but there's no euphoria. Why?
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garchi said:
Well, Well...Never say never =D

After 2 hours I got really impatient with the effects. They had already set in approx. 1 hour after ingestion, so nothing was happening which left a pretty bad feeling. The result: I redosed (slowly in a careful manner) and 1 hour ago I took ~110 mg 6-APB which are coming on right now...God damnit FINALLY what I was looking for ^^

EDIT: Holy shit, oooooh yes ^^ The initial 140 mg in total weren't even able to produce a kind of lasting, nice, low-plateau trip. Now I've got to 120 mg 5-APB and 230 mg 6-APB and finally the serotonin is rollin'
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Perhaps i haven't done enough to properly roll, but i've to say i found the bodyload @105mgs quite intense. Think it could be even worse with a single higher dose. I'm trying 100 followed by a second dose of 60-80 in 4-5 weeks and see what happens then!
 
Redosing for me with 6-APB wasn't all that effective, while I find with MDMA it is. Anything less than half my initial dose and I pretty much won't feel it at all, and I have to get pretty close to my initial dose to get much of a boost. On the other hand, I don't notice any tolerance to the side effects, so if I were to follow through with your idea, I'd have the bodyload of a 180mg dose but with the high of say a 140mg one.

Personally I don't think this is the best drug to redose unless the 7-9 hour roll isn't enough for you and you really want to go a long ass time with it.

What exact problems did you have with the bodyload at 105mg? Bodyload can mean a lot of things, and there are often lots of ways to deal with them. E.g. diphenhydramine or ginger for nausea, magnesium for muscle tension - switching up whether you eat or not.

I notice for me dosing on a full stomach with various drugs can lead to nausea and vomiting, and dosing while completely empty and very hungry can lead to stomach ache. A happy medium of being well fed but 2-3 hours since eating, or after a very light meal like a sandwich or two tends to be best.
 
I was nauseous, but not that bad, but felt me overall very agitated and messy, which subsided after approx. 1-2hrs. Reminded me a bit off coming up on shrooms/LSD. After that i was nicely, if not pretty much stimulated but without any euphoria, as said.

Funny thing is, the day after i felt different, more open, empathic and so on. I was defo more talkative and funny when interacting with other people, normally i'm more the "talk is silver, silence is golden"-type of human ;)

So what's your recommendation then? Upping the inital dose? To be honest, the lenght of the effects were more than enough for me, that's a factor i haven't considered with redosing.
 
Noodle473 said:
About how long does it appear to take tolerance to die off with 6apb?
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6-APB is an MDA analogue, and as such, like MDMA and MDA, once you've got tolerance, it's going to stick for a very very long time, and "losing the magic" pretty much permanently is likely to be just as equally possible as with MDMA.

If you want to avoid tolerance, I'd advise you stick to taking 6-APB once a month at very most, ideally far less than that.

If you already have tolerance I'd suggest waiting 3-4 months before your next experience if you want to get the most out of it, depending on the level of tolerance that may be slightly more than enough time - or that may be far from enough.
 
Great info, thank you so much jesusgreen! I love greens and the theory of jesus too, you must be an all around great individual. Is there any literature on why permanent loss of that magic occurs (chemically or otherwise) that anyone knows of? It pisses me off when such greatness is taken from me for seemingly no reason.
 
Noodle, in the short term use of serotonergics like MDMA, and presumably 6-APB will cause internalisation of serotonin receptors making them temporarily unavailable to new substances entering the system until they recycle back out to the surface of the cell. This is short-term tolerance, and why people tell you to leave at least a week between dosing say LSD and similar psyches. Repeated frequent use will cause down-regulation of serotonin receptor numbers over time. This is longer term tolerance,and a longer rest is needed at this point for receptor numbers to rebalance back out. In both cases you simply have fewer receptors available for your serotonergic DOC to activate. You also have potential neurotoxicity issues causing lasting damage which is not quite so recoverable from. Down-regulation and / or neurotoxicity likely account for the loss of magic and mood disorders frequently reported by heavy users of serotonergics like MDMA. The same mechanism is likely applicable here to the APBs.

http://www.maps.org/publications/2000_reneman_1.pdf

http://www.sciencedirect.com/science/article/pii/002839089290126A

http://thedea.org/MDMAatwork.html

http://thedea.org/neurotoxicity.html
 
Fantastic read Sepher, thanks.
Anyway, Im gonna make some holes in my brain tonight :D As its been over 2 months since I had some APB
 
Have a look at this TR on erowid. Apparently this guy did 450-500mg and nearly died.
http://www.erowid.org/experiences/exp.php?ID=96212

T+ 23:00 The rolling had been going on for a very long time now and I was feeling somewhat tired and the effects were wearing off, so we decided we would drop another small bomb each, this time around 50mg, said and done we dropped it and within an hour I felt some very strong warning symptoms, my legs started twitching, the sweating increased from what I am normally used to with high dosages of amphetamine and other stimulants including 6-APB, within 10 minutes I was in such a bad shape that I had to be helped to the bed, another 10 or so minutes passed until I realized what could have happened to me, and had happened to me, serotonin toxicity set in and in a desperate attempt to get help I got my rolling friend to call 911.

He tried contacting a mutual friend of ours over skype, this did not work out too well since he was unable to communicate properly with a keyboard, he was actually incapable of communicating with regular speech as well. By the time he had managed to call 911 my body went into a state of shock. My heart was racing at 200 bpm, my blood pressure was up by 200/?(I will check these numbers once I get my hands on the medical report from the hospital) it took the ambulance roughly 40 minutes to get to my house and by the time they got here 3 patrol cars were already on the scene.
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Seriously the adivce here is to not redose ever, unless the first dose was so low you dont feel it properly. This stuff is extremely dosage sensitive. Its not like MXE where you can take several more times than base dose and just lay in bed..
 
Thanks so much sepher! Is down-regulation of serotonin 5-ht receptors also affected if you take 5-ht before and or after an mda-analogue? I've read people say the hangover is less noticeable when you do this, but would taking 5-ht during this time make the effects of these drugs even less magic/euphoric over time?
 
good info sepher and jesus (if jesus was jew why the spanish name - John Cooper Clarke). Anyway my question tonight is is there a difference between 125mg of powder and a 125mg pill. I have had powder recently which I found underwhelming in some way, then I had a tablet that came free with a purchase. I'd been working on about 180mg apb powder but found recent experiences as draining as good. However the 125mg tablet has a much better effect and was deffo more enjoyable and I definitley felt 'warmer'. I cant really imagine dosing higher with the powder as the drain is already quite heavy. I am curious if there are 'additives' that make the BF tab so or is something else at work. Ive been pretty consistent in not redosing more than once a month.

Cheers for thoughts.
 
Noodle473 said:
Thanks so much sepher! Is down-regulation of serotonin 5-ht receptors also affected if you take 5-ht before and or after an mda-analogue? I've read people say the hangover is less noticeable when you do this, but would taking 5-ht during this time make the effects of these drugs even less magic/euphoric over time?
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I'm assuming you're referring to 5-HTP, the serotonin precursor and supplement commonly used in post/preloads. 5-HT is serotonin itself, and not something people take in pill form for the hangover. ;)

Taking 5-HTP is going to increase your serotonin levels so I can't see any way this would possibly reduce downregulation - if anything I'd see it having the opposite effect and worsening it, but most likely I suspect it simply will have very little if any effect.

5-HTP is more for treating the depression etc, but personally I've never needed it.

Eat a low tryptophan & high carbohydrate diet and you can naturally boost your overall serotonin levels and speed up your recovery. 5-HTP just causes a short peak in your serotonin levels and as such I think the actual benefits people have reported from it are more placebo than anything else, imo - unless they're dosing the stuff constantly all day.

mozzer said:
good info sepher and jesus (if jesus was jew why the spanish name - John Cooper Clarke). Anyway my question tonight is is there a difference between 125mg of powder and a 125mg pill. I have had powder recently which I found underwhelming in some way, then I had a tablet that came free with a purchase. I'd been working on about 180mg apb powder but found recent experiences as draining as good. However the 125mg tablet has a much better effect and was deffo more enjoyable and I definitley felt 'warmer'. I cant really imagine dosing higher with the powder as the drain is already quite heavy. I am curious if there are 'additives' that make the BF tab so or is something else at work. Ive been pretty consistent in not redosing more than once a month.

Cheers for thoughts.
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Sounds like the powder is lower quality and/or cut. It's also possible that the pill's dosage is understated - but this is very unlikely and usually the opposite is true. The finally candidate I'd say would be that you're eyeballing your powder and not really taking 125mg - the human eye is no substitute for a milligram scale - get one if that's the case.

You shouldn't really need as much as 180mg unless you already have a fair tolerance to MDMA related substances. I still find 150mg close to being too much sometimes and I've unfortunately really abused the drug over the last year.
 
Jesusgreen said:
I'm assuming you're referring to 5-HTP, the serotonin precursor and supplement commonly used in post/preloads. 5-HT is serotonin itself, and not something people take in pill form for the hangover.
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Yes, that is what i meant, thank you oh mighty wise one
 
^My sleep time was definitely shorter after coming down from 6-APB, but when I woke up I didn't really feel tired or hungover.
 
cheers jesus for replying. I have scales and measure the powder. Ive faffed about with dosages over time but like many I suppose i am trying to find the sweet spot still. Ive tried capping the powder, popping it in a rizla and chucking it in a drink. The drink deffo came on quickest (like a train in one instance), but it tastes so rancid ive been trying to avoid that. Also I like a Marlboro light binge when taking subs although i dont smoke usually, but smoking was way better when gelcapped or rizlad compared to the drink. Complicated when all you want is a quiet night. Ive never had any issues with my supplier and have about 9g 6apb at the moment, hence my question if someting could 'assist'. Ive mentioned elsewhere I tried a 6/5 combo but really could not tell any difference. I am tempted to chuck about 250mg in a drink next time and see what occurs?
 
6-APB is a strange animal... I tried various synths but none of them were really satisfying.. It definitely lacks a "push" and often brings me to a mellow but not happy low energy state.. Comedowns I noticed are much more gentle but can last up to a week. However, the lack of domanergic effects makes it easier to recover the energy, the mood however, it leaves in a pretty dark anhedonic territory. Dark chocolate and 5-HTP help to some extent to recover + daily exercise to get those natural endorphins going.
It's a strong substance but not well rounded and often times its effects are hard to pin-point, seem lacking but dosage increases may just leave a person more scattered / sick more than anything else.. It's better to not go over 80 mgs, the odds are more won't be better but worse. If at 80 mgs it is not good, higher dosage definitely will be worse.
 
20 hours before I could even think about sleeping would be quite typical for me. Doses of 100mg or less would not even touch the sides. It's true there's diminishing returns as you push dose so 250mg isn't massively better than 200mg but enough to be noticeable, but 200mg is a lot stronger than 150mg, and that's quite a bit stronger than 100mg. I regularly dose 250mg friday, will stay awake through till saturday, long, long sleep, lazy sunday then fine for monday back to the real world. No suicide tuesdays so far. I'd barely call it a comedown. Dose / response is very, very variable with this stuff it seems, effects very subjective.
 
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