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Dissociatives The Big & Dandy 3-MeO-PCP Thread: 3-MeO 4 Leaf Clover

Burn it up said:
I think I have mixed 3-MeO-PCP with almost every drug (MDMA, 4-FA, mephedrone, alcohol, heroin, weed, amphetamine, cocaine, tripts, phens...) without any strange reactions or negative side effects. Of course, the dose of 3-Meo-PCP I usually take is very low (1-2 mg snorted), so this might not hold for higher doses.

I just feel it polishes and smooths the crazy spikes of the other drug. Makes the experience more controlled, less anxious, more euphoric, more "intelligent" and less inebriating. It might be merely due to the positive psychological effects of 3-MeO-PCP, that make me feel more confident and comfortable, or it might be a true neurochemical synergy. I can't tell.

I also find it very soothing during the comedown of stimulants / empathogens. It just adds a kick of optimism and makes the end much nicer.

I also wonder, being this drug a NMDA antagonist, whether it has any effect in reducing or controlling the tolerance of other substances. I personally don't feel like my tolerance to other substances has decreased, but neither can I say it has increased.
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I've combined it with a lot of drugs too. I find that when combined with psychedelics, even in low doses, it will greatly potentiate the psychedelic, to the point that ~65ug of ALD-52 has multiple times sent me into deep trips, one of which resulted in me quitting tobacco. Mixing with stimulants seems to just make the stimulant more comfortable. Mixing with alcohol will intensify the alcohol. Mixing with weed greatly amplifies the weed.
 
Totally, xammy.

In regards to mixing this with amphetamines, has anyone else besides Solipsis had issues? When I first got my baggie of this stuff about 1.5-2 years ago I started doing doses of 2-6mg in a day along with anywhere from 10-25mg of Adderall, and after a week or two I noticed I'd developed numbness in the two smallest toes of my right foot, as well as numbness in my fingers. The fingers only lasted a day or two, as I only realized I had numbness while tripping on MXE/4-ho-met actually, stopped, and then it went away. Having intuited it must be a blood pressure / related issue having to do with the Adderall and dissociatives. But then the toe numbness lasted for 9-12 months afterwards. It's gone now of course, but it was a bit unnerving.

And that aside, I honestly just have yet to have a good experience comboing either adderall or vyvanse with this, or back in the day, MXE. It's just always seemed to produce this really weird headspace that I don't like at all, where I'm stimulated and my thoughts are moving quickly, but there's a confusion or dumbness that makes everything more difficult than it should be?
 
Xorkoth said:
I've combined it with a lot of drugs too. I find that when combined with psychedelics, even in low doses, it will greatly potentiate the psychedelic, to the point that ~65ug of ALD-52 has multiple times sent me into deep trips, one of which resulted in me quitting tobacco. Mixing with stimulants seems to just make the stimulant more comfortable. Mixing with alcohol will intensify the alcohol. Mixing with weed greatly amplifies the weed.
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Definitely! Last weekend I did about 10mg of 3-MeO combined with just a half tab of LSD (my usual amount is 2 tabs) and some weed and it was perfect.
 
Solipsis said:
The compound that makes ketamine such a good AD seems to be hydroxylated norketamine
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The question then is what is hydroxylated norketamine doing in the brain to achieve these antidepressant effects? As far as I know it is about interacting with the 2B subunit of NDMA receptors. Not only ketamine metabolites have these properties. Just look into the novel NMDA antagonists that are in research right now as antidepressants (for instance Rapastinel - https://en.wikipedia.org/wiki/Rapastinel).
 
Via mTor

https://www.ncbi.nlm.nih.gov/pubmed/26782056

I'm sure ketamine or rather its metabolites are not unique in this, as I said I am curious about MXE.. But nothing points to 3-MeO-PCP doing this. I've microdosed it for quite a while and it's effects on mood were transient. The typical dosage level and the difference in metabolite alone may make it unsuited as candidate, I guess even though not all that high doses of ketamine are needed for AD effect.

I suggest to be skeptical about it, not despite the signs missing to experiment with it in those ways. To really microdose 3-MeO-PCP would probably run into microgrammage if you make it equivalent, otherwise I think you should be careful not to exacerbate things like depression on a much longer timescale.
It's not a smart idea, seems like you would be better off trying it with very low dose IM deschloroketamine or something.

3-MeO can certainly be magic, but why would you get that enthousiasm mixed up in wanting it to be an AD when there are other options that make more actual sense? Think twice about any 'wonder drug' fantasies.

It's also worth knowing if permatolerance also implies resistance to this mTor mediated AD treatment. Then it would really matter whether you are a long term disso user to even be a real candidate. Does anyone know? Anecdotal evidence would be interesting to hear... I really wouldn't know, it seems permatolerance can partially mean resistance to hole (apparently via hyperpolarization channels with the NMDA antagonism), but not necessarily as high resistance to getting your mind wiped like on diphenidine.
 
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Well, mixing 18mg of 3meo with a few lines of ketamine and two weed joints with my cannabis tolerance lowered was disgusting. It was like the ketamine high was fighting with the 3meo high, and potentiated x10 by the weed, and ended beeing a confusing, dumb trip.

My mind racing at the speed of light and not beeing able to stop it or canalize that energy because of the ketamine confusion and slowness wasn't fun at all.
 
Adding just a bit of MXE to 3-MeO turned it into an almost overwhelmingly dissociative trip, too much. Well it was fun, but damn, unexpectedly intense.
 
When the dissociation wears off in combos, like 3-MeO-PCP + ketamine, the afterglow is something incredible. I remember laughing until I had tears rolling down to my thighs. Probably because I had just came home from a party with almost all of my close friends present whom I hadn't seen in a long time. So set & settings. :)
 
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Hello, does anyone have a comparison whether intramuscular has advantage over rectal with this substance? I know that with MXE they were on equal footing.
 
MSK said:
Well, mixing 18mg of 3meo with a few lines of ketamine and two weed joints with my cannabis tolerance lowered was disgusting. It was like the ketamine high was fighting with the 3meo high, and potentiated x10 by the weed, and ended beeing a confusing, dumb trip.

My mind racing at the speed of light and not beeing able to stop it or canalize that energy because of the hketamine confusion and slowness wasn't fun at all.
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Man, I wasted 500mg ketamine trying to hole like 5 hours after 15mg 3 meo pcp. 200mg ket usually puts me borderline amnesiac.

I was pissed, 200mg this time just felt like taking another 15-20mg 3 meo pcp. I smartly decided maybe I need another variable, plugged 40mg MIPT and sniffed 250mg more K.

Nada. Ive read others reporting similiar experiences.
 
psy997 said:
Totally, xammy.

In regards to mixing this with amphetamines, has anyone else besides Solipsis had issues? When I first got my baggie of this stuff about 1.5-2 years ago I started doing doses of 2-6mg in a day along with anywhere from 10-25mg of Adderall, and after a week or two I noticed I'd developed numbness in the two smallest toes of my right foot, as well as numbness in my fingers. The fingers only lasted a day or two, as I only realized I had numbness while tripping on MXE/4-ho-met actually, stopped, and then it went away. Having intuited it must be a blood pressure / related issue having to do with the Adderall and dissociatives. But then the toe numbness lasted for 9-12 months afterwards. It's gone now of course, but it was a bit unnerving.

And that aside, I honestly just have yet to have a good experience comboing either adderall or vyvanse with this, or back in the day, MXE. It's just always seemed to produce this really weird headspace that I don't like at all, where I'm stimulated and my thoughts are moving quickly, but there's a confusion or dumbness that makes everything more difficult than it should be?
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Yeah, i find that taking 3-meo-pcp even a day or two after dexamphetamine gives me a really unpleasant, confusing dissociation.
I would never combine the two after having this strange effect.
Your last sentence describes it well.
 
Having stated that it doesn't go well with amphetamine, how does it combo with MDMA? considering low doses of both.
 
I agree it doesnt mix well with stims. It feels clunky with cathinones, no synergy at all.

Also the therapeutic benefits are amazing, it really removes all fear.
I was able to approach an alcoholic issue that has been plaguing me for 10years. Im not yet completely through but have days without alcohol that i couldnt have imagined before 3moepcp ...

Mdma is special for therapy such as understanding and empathy, but this really helps one make a leap of action by removing the fear.
 
Xorkoth said:
I seem unable to get the hypomania from this batch, unfortunately. :( Weirdly, I enjoy the acute dissociation of higher doses on it MORE. It's very strange. I need to find myself some of the same stuff I had each time before, I really mostly value the low-dose hypomania aspect of this drug the most. If I had both I could utilize it either way. This batch is still mildly euphoric, but just more sparkly, with an MXE-like twinge to the dissociation I have never felt from it before. But the other 3-MeO I've had consistently produced a very specific, wonderful hypomanic euphoria at any dose, repeated countless times with great reliability. The dose is the same and the feeling of it is very, very similar. My friends all agree too. I don't think I'm imagining this and I think it really is 3-MeO-PCP. I want to send it in to be tested, but I don't want to spend the money because it's pretty expensive as far as I can tell (never actually done it, and I live in the US).
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If u don't mind me asking what state are u in? I only ask because I'm in colorado and bought what I thought was meth but it doesn't have the same hard hit when plugging and much faster comedown , looks like shards normally do though and melts the same on foil. I'm new to all this other than meth so I'm curious if any of these drugs look similar in appearance and how I can possibly figure out what this stuff is..i have pics needed...any advice guys!?
 
Hmmm, this thread has nothing to do with meth, this is about 3-MeO-PCP. Questions about meth should be posed in Other Drugs, but we don't really allow drug ID threads here since there's no way for anyone to be able to tell. My best advice is to get yourself a test kit. If you need detaiuls on how to test meth yourself, go ask in Other Drugs which I linked to.

Welcome to Bluelight though. :)
 
Wow, the hypomania really creeps up on ya with this one. Not quite sure how I got from "this isn't doing much" to "I'm gonna set the world on fire" but I'll take it.
 
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