The Big & Dandy 25D-NBOMe (NBOMe-2C-D) Thread

[zn13bt]

I would say that 25d is about 1.5x less potent than 25i so your sweet spot will probably be approximately 1.3mg. Test a lower dose first though.

That sounds about right. I ended up doing a buccal dose of 1mg today and it was a pretty mild experience, less intense than what I would normally get on 800ug of 25I. It was a little physically stimulating at this dose and I felt kind of a mental push to do something with myself instead of just lazing around my apartment all day (it's still freezing and snowing outside where I live, damn winter won't end) but otherwise not much going on mentally. I'll probably try 1.2mg next time.

 

[Anon0631]

^ Seems to me that 25d is one of those break-through drugs in the way that salvia is and (IMO) DMT isn't. There's a point where the effects go from relatively useless to definitely useful.

I'm not sure where that point exactly lies with 25d though as I've only taken it twice. I can definitely say though that 600μg (insufflated) is on one side of this point whereas 2mg (insufflated) is on the other.

I would be very interested to know where 1.2mg gets you. Be sure to give it a decent (2.5-3 week) tolerance break.

 

[tippa]

Seems like theres a huge variation in what people seem to find a manageable dose here so i wanna add my two cents. I got some absurdly strong 2.5mg blotters and let them sit for a week or so because what I read on this thread made me question whether or not the person I got them from was trying to kill me... but I spent a solid week with some other phens to build a little tolerance, then finally gave in and gave it a shot (I was fairly warned). Felt it within 15-20 minutes, by an hour every aspect of everything was intense. ate a whole pizza and a sub at this point. I love, love, love the headspace this one puts me in, just incredible. Visuals too. I think 2.5mg is a perfect dose for me, but then again I am somewhat reckless at times. Must warn you all though, my hands and feet are kinda cold, and anyone sensitive to vascoconstriction should take note of this and probably not dose this high.

 

[zn13bt]

I got around to trying 1.2mg (buccal) today. Turned out to be surprisingly more intense than my 1mg experiment a month ago, to the point where I'm questioning the accuracy of my liquid measurement methods. It's very stimulating mentally and physically, and I'm experiencing a lot of muscle tension and some weird pinching achy feelings in my chest. I think I may need to try out weadazoid's ideas about eating foods high in magnesium and potassium before taking a dose like this again, it doesn't feel like it's agreeing with my body too well.

The weather isn't exactly helping my mood today (it's fucking snowing or sleeting or something outside right now. Fucking Upstate NY). But I don't feel like the 25D is particularly pushing my mood in one direction or another, it seems to be pretty neutral. I'm definitely missing the positive mood lift I get from 25I. Also barely any visuals at this dose.

Not sure yet if I'm going to be taking this substance again. At this dose it seems like a lot of stimulation and body load without enough positive mental or spiritual qualities to make it worthwhile. I'm kind of disappointed after how long it took for me to source this in actual chemical form and not on some dodgy blotter, and given the comparisons to DOM I've seen other people make. Oh well.

 

[azzo]

At 1.2 mg buccal i'm not surprised you didn't experience strong visuals, it's a low dose ime, but well on me it didn't produce all those bad side effects.
Usually 1.8mg snorted are enough to produce good visuals, and after 2mg range they become really strong and stunning.
As for the mood lift 25I is far superior imo, no matter what the dose is, the euphoria i get from 25I is just stronger.
Can't help on the side effects, ime 25D isn't the worst in that in the Nbome family, 25C>25I>25D>25B for me, so i just avoid 25C because i can't tolerate the extreme muscle tension and cold feeling it gave me.
Last time i snorted an old solution of 25I i had made many months ago and at 1 mg it wasn't coming up strong so after 25 mins i added 1.8mg of 25D and the intensity increased fast to a full +++ with a lot of visual i wasn't experiencing before, it was a nice trip and the main effects were due to 25D and not I, anyway they mixed well together.
Maybe you should try another ROA instead of buccal, don't know if that can help with the side effects.

 

[lenses]

Does this have the smart drug/learning enhancement effects of 2C-D?

 

[Anon0631]

As far as I'm aware, low dose use of 2c-d hasn't ever been shown to have a nootropic effect. It's just some people's opinions.

 

[David the Chansey]

Placed 3x1mg 25D-NBOMe blotters in between my gum and cheek 10 minutes ago. I will write a trip report later. Don't worry, there will be no live trip reports.

 

[bloodshed344]

As far as I'm aware, low dose use of 2c-d hasn't ever been shown to have a nootropic effect. It's just some people's opinions.

I've never done 25D, but I have done 25C and 25I and I feel like these nbome drugs would be much more fit for a nootropic type use than any 2C. However, there's one big downside which means no, you won't be able to use them like that. The massive tolerance increase prevents it from being used even bi-weekly, you might could get away with doing it weekly if you keep your doses low and don't do any psychedelics. Doesn't sound worth it to me.

 

[David the Chansey]

Ok, so I tried 5mg and it is clearly evident that this was too much. Normally, nbomes flush my bowels. However, on the come up this time, my body was under so much stress that I couldn't release anything, causing me to have painfully full bowels for an hour. After release, everything was ok, but it was difficult to enjoy the rest of the experience after such trauma. 3mg was fine (for me). I have to add: YMMV.

 

[Achten]

Yesterday I took 800mcg 25DNBOME bucally, HPxx complexed, if I remember correctly. No real tolerance, expect maybe from 30mg of aMT 16 days prior.
It was never overwhelming but at times it was intense. For the most part however it was extremely mellow, erotic, chill but awake. No real visuals, although the night sky looked very interesting. Mostly color saturation however. I felt really good in my body, I think this was the erotic aspect. Yoga felt awesome.
First alert at 10 minutes or sth, onset at 30-45minutes, coming up finshed at T+1h30 somewhere. At T+4h30 I was still very much tripping, although maybe slightly on the comedown. Sleep was easy at T+8h
Little headfuck, extremely "content" feeling (reminiscent of MDMA), beautiful colors, no visuals, music appreciation was up.

Nice experience, would repeat, at the same level. Although it is one of the "easier" NBOMEs, I'm not inclined to dose higher. Other stuff might be better suited. I did think about throwing mushrooms in the mix but since this was my first try at this dose I passed. I figure 4HO tryptamines would be very nice though. Any reason why this not should be done ?

edit: high quality cannabis was smoked throughout, and did synergize wonderfully with the 25D. Body high was intensified highly after smoking.

 

[《Plasticity》]

^ Sounds like fun, 25D is really a smooth psychedelic...it's the only NBOME I will eat. I've mixed 25D with Metocin and Psilacetin and they mix pretty well, especially the psilacetin combo. I know Solipsis said that he got vasoconstriction from a small dose but I've never noticed a hint of vasoconstriction even when combo'd with stuff like 6-APB and Moxy (Fantastic combo btw, one of my favorite three drug combo's), which should in theory be a recipe for nasty VC or at the least some really stiff muscles. If 25D was dosed in the 20mg range, was orally active, and I was told it was a 2c I would believe it. It's a bit shallow but alot of 2c's are for me, 25D gets a B- rating for me...good stuff! Though there's definately better substances...

 

[Jesusgreen]

^ Sounds like fun, 25D is really a smooth psychedelic...it's the only NBOME I will eat. I've mixed 25D with Metocin and Psilacetin and they mix pretty well, especially the psilacetin combo. I know Solipsis said that he got vasoconstriction from a small dose but I've never noticed a hint of vasoconstriction even when combo'd with stuff like 6-APB and Moxy (Fantastic combo btw, one of my favorite three drug combo's), which should in theory be a recipe for nasty VC or at the least some really stiff muscles. If 25D was dosed in the 20mg range, was orally active, and I was told it was a 2c I would believe it. It's a bit shallow but alot of 2c's are for me, 25D gets a B- rating for me...good stuff! Though there's definately better substances...

When you say you've never noticed vasoconstriction do you mean you've monitored your blood pressure to check for increases? Because if not you don't really "feel" vasoconstriction until it gets pretty severe. A lot of people are currently taking NBOMes at doses where their heart is in danger of giving out and don't have any clue they're in danger because the euphoria covers up the fact that their blood is struggling to flow properly. Just worth bearing in mind.

I used to think I could "feel" if a substance was vasoconstrictive or not but it turned out to be more related to muscle tension and how much of that a substance caused - or general bodyload. Substances that felt euphoric and nice on the body I always felt like they had to be safe on the body and then I'd get a shocker a lot of the time when I looked at my blood pressure, 25C-NBOMe was the worst one to date. 6-APB is pretty bad for blood pressure too so honestly I'd really avoid comboing with stuff like the NBOMe series, often side-effects can compound just as much as the good effects do in such combinations, and just because you've done it before safely doesn't mean it'll be safe to do in the future.

On that note - if anyone here has kept a check on their blood pressure and heart rate (with a machine not a finger) during their experiences can you suggest what type of dosage starts getting your blood pressure too high and what you would consider a safe dosage?

For example 1.2mg 25C-NBOMe had my blood pressure in the hypertensive crisis range within about 10 minutes of putting the tab under my tongue, so I promptly spat it out, meaning I actually dosed quite a bit less than the 1.2mg, and still my blood pressure kept rising until I took some benzodiazepines to lower it. 2mg+ has put several people I know in the hospital. On the other hand 0.8-1mg 25C didn't cause my blood pressure to rise more above normal than a cup of coffee would make it rise and 1mg ended up being a perfect dosage. With 25I, 1mg was even more a perfect dosage and also didn't seem to raise my blood pressure at all. How does it compare with 25D?

If not a single person here has ever monitored their BP/HR while on an NBOMe I'd say it's really worth doing as the nice body feeling can mislead you about what's going on inside - but if really no-one here has done such a thing, what would you say the *lowest* dose sublingually you would consider taking, for just a light experience - and what's the *lowest* dose you'd take for a full experience with nice visuals and all?

The reason I'm asking is I have a 2mg tab of 25D-NBOMe to try at some point, it'll probably be a while still so you guys have plenty of time to answer, but I don't plan on taking the whole tab given my experiences with just 1.2mg of 25C, and was thinking on something more like 0.5mg with a 0.5mg redose for the light experience, and then 1mg in one dose another time for the full experience. How does that sound?

 

[《Plasticity》]

I've never monitored my BP with any machines but I can usually feel if I'm hypertensive. I do However frequently check my HR and it never seems to jump very high with 25D or 6-APB (though the combo brings my HR to about 120-130 BPM at the peak). For me 25D is very smooth whereas 25i was utter hell. I could definately feel the vasoconstriction at 800mcs ) of 25i and it made me not want to explore the NBOMe's any further, with the exception of 25D because I found it so smooth. When I say I've never noticed VC I mean that my limbs never go cold, my muscles don't get stiff, and I can move fluidly. I can definately tell if I'm experiencing vasoconstriction, the first sign is usually cold feet, then it progresses to stiff thigh muscles, and if severe I feel like walking ten steps equates to running a mile .

Keep in mind though that 25D is not nearly as potent by weight as other NBOMe compounds so 1mg won't provide a full experience, likely. I say you take 750mcs one trip and 1.25mgs next trip as this should show you what 25D has to offer. Also, spreading your doses with 25D or any NBOMe is worthless. I tried to take 1mg and follow it with another mg 45mins later and it never progressed past what I would've felt with a single mg. Your best off taking a single dose, anything else is more likely than not gonna prove to be a waste of material IME.

Edit: I should mention that I always supplement with magnesium, potassium, and CoQ 10 whilst also smoking lot's of cannabis which may be why I don't experience vasoconstriction very easily with most substances. I also keep somewhat active whether it be going on a bike ride or a walk or spinning some poi/glowsticks. I also stretch every hour and drink lot's of fluids including pedialyte (look it up if you've never heard of it, basically a drink loaded with electrolytes and other goodies).

 

[Jesusgreen]

My heart rate on 25C didn't jump too high it was just the blood pressure, and I certainly didn't feel it past the euphoria. I think what most people feel that they think is vasoconstriction is actually muscle tension, like DOxs, vasoconstriction causes your blood pressure to rise and I've never noticed any real spike on DOB or DOC while I certainly felt like they were causing vasoconstriction, but I think it was just muscle tension and such. With bk-2C-B I thought I had really bad vasoconstriction too and my blood pressure actually *dropped* from normal, along with my heart rate, so there certainly wasn't any to be had there.

 

[《Plasticity》]

Say what you will but I'm pretty positive that for me 25D, in reasonable doses, doesn't cause any significant spikes in my vitals...at least to the point of worry. 6-APB definately causes more troubles than 25D, though for me even that doesn't really cause any significant dangers worse than MDMA would give. Can you really not feel if your hypertensive if your on a substance that leaves your mind in tact like say... a medium dose of 2c-c if in theory it caused any hypertension? I sure can as long as I'm not too far down the rabbit hole but like I said 25D leaves me pretty damn lucid, it's a very shallow substance. 25D is also not overly visual or euphoric either...it's more of a chill at home or go for a walk and enjoy nature kinda drug for me... not distracting in the least IME.

aMT, another shallow psychedelic I've taken quite a bit, always causes me to get pretty hypertensive during the peak which for me is VERY euphoric and there is no need for a BP cuff to know that. Same goes for amphetamines, though if your on a substance that leaves you incredibly wrecked then it gets pretty hard to even check your HR with a timer. I don't see how knowledgeable trippers could mistake cold limbs and the inability to stretch them without feeling like your gonna break with sore, stiff muscles...though it does happen. Maybe the "walking seems like a monumental task" thing but even that I'm positive is vasoconstriction in my case as I only get this side-effect on lysergamides (LSA in particular) and harsh phens. Stretching becomes painful at this point with no relief from any amount of acetaminophen. 4-subs make me pretty damm stiff and I've never had this effect on them as well as other tryptamines, only heavily vasoconstrictive drugs.

Other significant things I should've added is that I'm a kratom addict therefor I'm always on maintenance doses of that so IDK how that affects anything but I do know kratom contains a vasodilator. Also, I make a habit of nasal dripping small amounts of etizolam (1-200mcs) every couple hours if I'm taking any risquè combinations. Anyways... if it makes you feel better I'll take a trip to the local drugstore and use their free BP cuff and check my vitals next time I'm on 25D, though I don't have any plans to take any soon... it's pretty damn lucid though so I would have no troubles blending in with the sober folk though my pupils may be a dead giveaway lol, still though ymmv... especially with all my personal factors at hand

 

[zn13bt]

I agree with Jesusgreen, a lot of posters say "vasoconstriction" in their reports when what they really mean is "muscle tension".

 

[《Plasticity》]

While that may be true, I don't think it's very hard at all to tell the difference on something like 25D, although less experienced trippers may have a hard time distinguishing the two I guess. Kinda reminds me how if anything goes wrong with a monoamine releaser it's immediately serotonin syndrome … Do any other experienced trippers have trouble distinguishing between VC and muscle tension? I don't think it feels similar at all.

Edit: I should've made it more clear in my above post... I'm speaking for myself and 25D only, I'm aware of people easily confusing the two and how difficult it gets to tell if your experiencing any dangerous spikes in BP/HR on other substances that aren't nearly as lucid. I just find the feeling if VC pretty unique and very much unpleasant, moreso than muscle tension. I edited my post for clarification.

 

[TheEmperor]

Hello everyone. I have very little information on this drug and do not have much time to scroll through this entire thread (so I apologize if my question has already been answered), but is this drug harmful?

How safe is this drug?

How does it compare to other drugs (safeness wise)?

Is this a good drug to start out with?

Basically how dangerous is this drug and what are the harmful side-affects to it? Any permanent side-affects?

Thank you to anyone who answers this (or who can "quote" a previous comment on this thread that would answer my question)!

 

[lamanogaucha]

This is the only 25x that I've tried, and it will almost certainly remain the only one. I tested it twice. The trips were good, but nothing to write home about. They also elevated my pulse to rather uncomfortable levels...

The safety profile of this compound is unknown, but it is prudent to assume that it isn't anywhere near as safe as virtually all other psychedelics outside of the 25x family, including NBOMe's, NBOH's, etc.

I suggest that you skip all of them. True, safe jewels can easily be found elsewhere.