Tried this chemical, thoroughly and entirely holed on my first shot, at 80mg I.M. (intramuscular is the only way to use short acting arylcyclohexylamine anesthetics, otherwise you're wasting your shit 8) )--not very manic at all. Very comfortable. During ramp up to peak-blast-off, it feels almost like a huge dose of nitrous- w/ laughter & all; until things start to get a bit weird & then bam! your ego is reduced to the inner uniform substrate that is innate in all manners of things.
As the universe began to re-materialize itself as separate states/manifestations of expression w/ distinctive borders & boundaries within it, & one's own sense of self returns, was left with a very deep & intensely emotional "connected", unified state of mind, especially towards family & friends--very reflective (err, well, as reflective as one can be w/ such deconstructed & disorganized thought processes lol)
Very nice and easy come up:
-Effects start 3-4 minutes after injection..
-Very very pleasant ramp up to hole by 20 minute mark.
-Then hole starts to subside around +60-70 minutes.
-After effects till +2 hours; baseline by t+4.5-5 hours. Very pleasant afterglow. Slightly stimulatory, but in a relaxing, anxiolytic way.
Get sub-hole like effects, similar duration, w/ next day use; 120mg I.M.; experiments stop there to reset tolerance.
(Note: I had a significant previous tolerance to 3-MeO-PCP apparently; although i don't remember much of the 4 month binge, other than waking up w/ seizures & catatonia in clonazolam withdrawal, 3 weeks into a hospital stay at University Hospital of Clev. But hadn't used for over a year. Plus PCP & their analogs tend to always make me black out & redose compulsively. Prev diss experience- MXP, DXM, ketamine (years ago, never holed, never explored properly), & nitrous. This was by far the most pleasant & will repeat; looking forward to trying the deschloro cousin

)
Rx's/frequently used meds:
1-1.5mg buprenorphine daily
14 days into 4800mg/day gabapentin cold turkey kick
Occasionally 5-7mL of 2m2b used for sleep
ZERO used of cannabis or ethanol.