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Lysergamides The Big & Dandy 1P-LSD Thread - Volume 2

Thanks for the advice, I do have an unusually fast metabolism, and a low psychedelic tolerance, also it has been confirmed the propionyl group is cleaved off by being hydrolyzed in the body right? So basically it converts to LSD-25 at some point when the group is broken down.

I was thinking 75ug just because of that fact that some people are having crazy experiences from 75 to 100ug, and with me having a lot of recent psychedelic experience, I do not have lysergamide experience besides 2 weak acid trips that didn't induce anything worth while to report about. Why not start slow? I'm in no rush but in reality there's probably not too much difference from 75 to 100 just a more developed experience we'll see when the time comes ;)
 
eclipse3130 said:
Thanks for the advice, I do have an unusually fast metabolism, and a low psychedelic tolerance, also it has been confirmed the propionyl group is cleaved off by being hydrolyzed in the body right? So basically it converts to LSD-25 at some point when the group is broken down. ?
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No that's not true studied on mice have found that 1p-lsd is active on its own meaning it doesn't fully rely on your body metabolizing it into lsd. But it was also found that just <30% of it is actually metabolized into lsd. Which explains why different some people feel it more so than others.
I find it weaker than lsd. But Ald-52 on the other hand is identical and I guarantee more than <30% of Ald-52 is being metabolized into lsd only AFTER you ingest it.
 
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I am still experimenting with taking a 16th of a 100mc blotter in the mornings. Thus is, about 7.5micrograms first thing in the morning. Still having the same great results. It makes my day much easier and exciting, gives me drive for everything i want or need to do. I tried a few times with some mxe and got good results, although it makes me definitely manic... but not in a pathological way, but just a bit overexcited.

I am definitely going to keep with this regime for a while, having a few days off here and there, but generally having a 16th of blotter 4/5 days a week. I need less cannabis because it hits me stronger now
 
^interesting cosmic._.ape - keep us posted.

I enjoy the results from this kind of microdose myself (of various PDs) but only do so rarely. I would do it on a nearly regular basis if I knew for sure that it was perfectly safe. It would be nice if there were more long term case studies of microdosers out there, so we could have an idea of what (if any) risks there are.
 
Bigazznugz said:
No that's not true studied on mice have found that 1p-lsd is active on its own meaning it doesn't fully rely on your body metabolizing it into lsd. But it was also found that just <30% of it is actually metabolized into lsd. Which explains why different some people feel it more so than others.
I find it weaker than lsd. But Ald-52 on the other hand is identical and I guarantee more than <30% of Ald-52 is being metabolized into lsd only AFTER you ingest it.
Click to expand...
I've got that paper and ive given it a decent read and nowhere in it does it say 1p-LSD is active in it's own right , or at least that I've found in the paper plus aren't try still to do the study with human serum to obtain results more applicable to humans?
 
Hello guys.


Please, do you have some experience with 1p-lsd PELLETs (150micro) ?
May people write reports on this substance, but only related to blotters....as ar as I could see of course.
I would very appreciate if somebody can share some info about PELLETS and if there can be some difference.....mainly regarding the quantity of subtance. It's written, that there is 150 micro.... but is this info trustful ?? Can happen that there will be significantly more or less ?
I hope that not, but who knows....as people usually buy it in form of blotter.

And also, how PELLET is supposed to be eaten ? Should I just swallow it or put to water or something else ?


Thanks a lot.
 
I have used the pellets and just swallow as someone said. They are good and 150ug a very nice dose if you have some experience with this chemical. It could be a bit intimidating if you have none.
I have to say it is a lovely chemical and the best legal you will get though i have not had the ald-52 yet
 
Thank you zombywoof. Thanks for reply. I read from some guys that I should avoid pellet etc....I don't understand why, it's from the same vendor as I had blotter....and blotters were OK.
I fully agree with you that these subtance can be intimidating. What I hate on this subtance, that it's TOO MUCH SPEEDY. Do you know how this can be eliminated ? Mental effects are OK, not so strong compared to real deal, but body load is bad, always.

Do you know what helps regarding body load with 1p-lsd ? Maybe I shouldn't eat whole day, or should I eat something special, which should help with body load ?

.
 
Cant say for sure as some trips i have had tummy pains and others not though if i remember correctly it was better to have ate something light an hour or two before tripping. as for the bodyload i found stretching really good and some deep breaths. Oh yes headphones on some good sounds and all the negatives just slide away. Heard something about grapefruit maybe increasing effects but never put it into practice yet. I would say people will put you off the pellets just because of the price as its well above buying blotters
 
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Thank you. Yes, price is really very high for pellets, it's strange...maybe to make pellet is little bit complicated.
Some guys are telling that in these pellets can be some DOx etc....but honestly why ? DOx is not legal as far as I know so if some UK vendor put into pellet some DOx or even nBome, then they can be in a problem I suppose.

Thanks for yout tip abour stretching, I will try. I don't know why, I have still under influence of 1p-lsd fear about my body...not sure if it's only mental thing or it can really do some bad things to body.
 
it depends on how you interprate the information. i cant find words to explain it but evidience is suggestiong that 1p-lsd is active by itself before being converterd to lsd via the liver.[/QUOTE]

True I'll agree that it could be interpreted different but even top researchers in the field such as profs Nichols and nutt both say that due to the propnyl group added it wouldn't fit in the receptor until cleaved but obviously this is only a theory . I honestly think that either the conversion rate is much higher than in rats or that you could be right about it having it's own activity because from a half tab I've had some very visual experiences such as the room turning entirely green for a couple minutes was class but this could have also been due to me having eaten half an hour before dropping which I've read can highten the experience
 
One more question, if I can pls. Regarding Vazocontriction. I had this negative body effect when I was tripping on half nBome blotter. Never ever honestly, it's a shit thing. But unfortunately, last time on 200micro 1p-lsd and little bit of smoking mary jane, I had vazocontriction again.
Or at least I suppose it was vazocontriction. I felt pale in one of my foot-fingers.

Do you have some hints/tips, how to avoid vazocontriction ?
 
maybe it's really only mental issue, but under its influence it's quite hard to differentiate if it's only mental or real. or if to worry or not.
But thanks again regarding stretching advice....1p-lsd as itself is quite speedy in my opinion, so probably it's better to do something and not to sit only and fear about body.
 
I think it's just anxiety, come ups on acid are long, at least for me my extremeties turn white and my hands shake and sweat excessively. I know normal lsd is pretty speedy in itself.. compared to other psychs it keeps your mind awake for a good 10 hours, unable to sleep. Not a part I particularly enjoy but it goes with the experience, but you're saying 1p is even worse for this? Maybe it's just because of the purity and dose you haven't experienced before, I also heard ETH from someone that it is even more stimulating, almost too stimulating but who knows can't say til I try it myself. Everyone's different set and setting are the biggest role, who knows the people taking these substances most likely aren't doing true research on them comparing to the other lysergamides in the sense keeping the same set and setting but even then experiences can differ, but some are doing this as well.

As for the 1P being active I thought I read somewhere it was somewhat active by itself under 30% that of LSD in human serum, and just because if it's active doesn't mean it wont attach the receptor until the group is cleaved, just part of the molecule is active why the other has to still be hydrolyzed. Wasn't it 38% bioavailibiltiy to rats as humans that's obviously higher so it must have something to do with metabolism and the way the body processes the propionyl group. This could explain for some how you feel it so soon, but a slow build up and come up to the peak, maybe you're instantly absorbing 30% of initial LSD of the chemical that is active in its own right and must wait for the rest to be hydrolyzed by the body. Could be the answer to it showing up on ehrlichs 4 hrs later or just not as intensley as only part of the molecule is active. Maybe the rate at which we absorb the lsd changes intensity, maybe some don't fully cleave off the group, who knows I for sure don't know anything in fact, just speculation
 
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Hi Eclipse.
Yes, right. I simply feel 1P much more speedy than any other thing (lsd or shrooms). But this isn't main problem. It's not pleasant and somehow ruin the trip, but I can live with it. Problem is mainly feeling that 1P is simple felt in body somehow....and it's not pleasant. Sometimes it's maybe liver, sometimes kidney, simply some part(s) of trip is usually connected with these feelings, fears etc.

On shrooms it's something else, first part is connected with stomach problems and later on sometimes with fear of intoxication. But again, it's normal on shrooms, as basically, psilocybe mushrooms are toxic :-)

But when I compare real lsd with 1P for example, 1P isn't such clean to body....in my opinion. I usually can feel some pressures in various parts of my body....not the case for real lsd...but with 1P yes. And problem is, that I don't know in that situation, if I should fear or not, you know....

But as I wrote, maybe it's partially impacted by mind setup. who knows....:-(

I suppose this is destiny for every tripper....you never know what will occur and how it will affect you.
 
Peacephrog1972 said:
How long have you need doing this cosmic ape?

And what are the overall effects you feel from it?
Click to expand...

What I do is to cut a blotter in two, then divide the two parts and divide again until having 16 little pieces.
Day one i took the smallest piece, and then i would take a progressively bigger piece everyday, until I took the biggest piece the 16th day.
Then I repeated the pattern; I have already consumed three 100mcg blotters in 2 months and a half (11 weeks)

I used to drink coffee everyday. Not anymore. I feel more focused, more energy, sleep better, enjoy higher libido, more drive but, the best of all, is this easiness to make connection in mental and real life. Like, business connections. I feel like i can see opportunities everywhere. It feels like a very good nootropic, so far.

I've found out that, for me, the best time to take it is right after waking up, before breakfast.
 
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