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The Big and Dandy 4-AcO-DMT thread - New incarnation

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Hi everyone, I have recently acquired some 4-AcO-DMT, and I'm very excited about experimenting with it. I was wondering, does anybody have any experience with injecting this chemical? I know people have but I can't seem to find any reports. If you could give me any ideas on dose, effects, and whether to go for IM of IV, it would be great. I will probably however experiment with oral administration first.

Thank you! :)
 
I tried this chemical for the first time during this weekend and I had a very good time. The dose was a tiny 10 mg to feel it, and then an equal refill taken over the course of half an hour, about 2 hours later.

I started to feel the effects after 30 minutes, and they continued to intensify for about an hour. These effects were tranquility, peacefulness and a philosophic state of mind rather similar to what one might expect from the come-down - that is, with none of the anxiety I associate with come-ups. After about 3 hours I started to enter a rather negative frame of mind, which, to my extraordinary relief, could be aborted by sharing my feelings with my trip mate (who was on the same dose). After this I had a pleasurable time again, playing videogames and talking with my friend. At t+5, effects were largely gone. I drank some beers during the course of the evening and became slightly drunk by the time the trip was over. I slept well and now (two days later) feel remarkably fresh, mentally.

Visuals: Nothing spectacular. Diffuse patterns playing around in my field of view, things looking cartoonish and confusion of physical attributes. Keep in mind this was a low dose trip which I would describe as a 2, borderline 3 on the shroomery scale.

Pupil dilation: Heavy. Less than with LSD or LSA seeds, more than with 4-HO-MET.

Bodyload: Almost none. Heart rate decidedly increased, but not to an unpleasant degree. Vasoconstriction created some stiffness, but was bearable. No annoying peripheral stimulation whatsoever.

This is a very interesting compound. I am eager to try it again at 26 mg, with the company of 2 tripping friends in a very good setting; possibly with a sober trip mate.
 
4-OH said:
Hi everyone, I have recently acquired some 4-AcO-DMT, and I'm very excited about experimenting with it. I was wondering, does anybody have any experience with injecting this chemical? I know people have but I can't seem to find any reports. If you could give me any ideas on dose, effects, and whether to go for IM of IV, it would be great. I will probably however experiment with oral administration first.

Thank you! :)
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Here's my gonzo movie review of "Inland Empire," as informed by IM 4-AcO-DMT:
David Lynch’s film “Inland Empire” finally came to my city, and I met it there with 12mg of 4-AcO-DMT loaded in a syringe...

Lynch’s film is a monster lurking in the shadows of a Narnian wardrobe, a world of overlapping fabrics, strange connections made in the dark, and holes in silk, burned through with cigarettes. A world I have always wanted to swim in since I was a child reveling in the terror-charged wonder of nightmares.

“Inland Empire” is a kind of Dadaist meta-film and to say the 4-AcO-DMT added a few layers to the beautiful, self-referential absurdity would be an immense understatement. The theater became an extension of the film, with the creaks of the seats of patrons, unaware and uneasy, becoming the strain of the building itself trying to contain this wild thing from gnashing its way out of the screen. Intermittently the entrance doors would open, allowing phantasmagoric shimmers of light into the darkness as unknown figures quietly shuffled in and out. And my mind was just one more screen, one scattered across these many worlds, letting in dark figures and shimmering light from the cracks at the periphery of my vision. In the film the characters become detached in time. Likewise my mind seemed temporally extended, aware of my how my past was influencing my perceptions and how these haunting images would become slotted for reappearance in the future of my dreams.

The experience and the film were in turn, profound, grotesque, beautiful, hilarious, discordant, and disturbing. Strangely, the disconnected, dream-like images were responsible for the film’s greatest sense of realism. There was something of truth in tumbling through the wardrobe, awash in the plurality of its textures and its shifting threads, something about the depth of an image and the illimitable moment. They are like a puzzle whose completed picture is that of yet another puzzle whose pieces are skillfully hewn together in conflict with their forms, yet the exquisitely fragmentary image produced is a fuller representation of its subject’s reality than the one demanded by objective coherence.
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IM is around double the potency of oral, though there are differing opinions on this, and the onset is significantly more intense. For me 12 mg has about a 2 hour peak and is pretty much done at around 4 hours. There are IV reports in this thread too, though I think in the report they used 25mgs, which is an extremely high dose, and was likened to smoked DMT.
 
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Somewhere between 22-24mg of 4-aco-DMT was eaten by, ok, well, I ate it. ;)

It was degraded and brown and clumpy.

And it gave me the most beautiful, simply astounding, soul healing journey!
Visually I have always found 4-aco-DMT to be so beautiful. At 22+ mg it was spectacular. I prefer these style and quality of visuals over just about anything else, even smoked DMT.

I felt so amazing and ended up dancing to Phish for hours, truly getting down!

Did a K-hole dose of that about 3.5 hours in (still quite tripping).... simply astounding.

I cannot say which is better, 4-ho-DMT or 4-aco-DMT. I find them both to be incredible allies in this journey we call life.
 
4-aco-dmt is something very strange and very special, maybe its just a mushroom experience, maybe not. but whatever it is it has had a larger impact on my life than any other drug. it unleashes the lucid flow of ideas in a way that only mushrooms dmt, dipt and 2c-b have for me in the past.
 
does anybody find the pull toward the primitive/ancestral man is very strong with this one? (stronger than psilocin which seems more technological in kind).

This drug makes me want to roll my muscles in a fluid pattern and dance to the tribal beat.
 
Can the 4-aco-dmt be white? I just received a white stuff whereas one year ago i had a tan stuff from the same vendor. Can it be a mistake? Or anyone have a white stuff which works?
 
I believe I recall hearing about a white batch as well as a tan batch, but I could be mistaken. The only batch I have received was tan.
 
Gaian Planes said:
has anybody combined this drug with LSD and if so what did you think? I'm thinking about sniffing some peaking on a couple mics of L.
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It's one of my favourite combo
for me they go perfect together
I usually sniffing around 6-12mg of 4-aco-dmt after the main peak, it adds some new colours to the expirience:)
 
^^
Agreed, the visuals are sharper, brighter, and more sparkly.

Though I have definitely got an "Alice in Wonderland" feel from it as well ;)
 
Gaian Planes said:
has anybody combined this drug with LSD and if so what did you think? I'm thinking about sniffing some peaking on a couple mics of L.
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It goes great with LSD. I've only taken 10mg orally while already on a couple of blotters, but the results were explosive.
 
This one's great! Took 16mg off-white powder and was happy with the dose. No stimulation, no anxiety, no nausea, all three take me over on phenethylamines. Great full visual field open eye patterning and meshing. Unbelievably beautiful actual landscape. Closed eye 3D non-interactable visuals. Metaphor of the human species as a retrograde amnesiac patient, discovering where it came from, profound.

Took a couple hours to really take off, and was down in six from dropping. There was no come-down, just a reinstatement of reality. I think because there is not the same stimulation as there is from LSD it doesn't leave you strung out.
 
Man, it seems most people find 4-AcO-DMT to be significantly longer than 4-HO-DMT/mushrooms, as well as slower. I must be a rarity because for me it's like a rocket ride, definitely a step faster than 4-HO-DMT and so rapid that it reminds me of a slowed-down DMT flash, with the jewelled visuals and the really high-frequency, intense body buzzing. I like it and have had some amazing experiences on it (including a +4 where I was completely in control of myself but directly connected to the universal mind), but I wish I could get the variety of effects that most describe...a slowed-down, friendlier mushroom/psilocin would be nice!
 
are you sure you didn't mix up samples? =D

I really don't see how you could find what you found. I think it takes longer because the 4-aco-DMT breaks down into 4-HO-DMT in the body and then crosses the BBB (the difference in effects are a result of the difference in absorption rates).

4-HO-DMT hits within 10 minutes, 4-aco-DMT takes 15-20 and the onset is much more gentle/easy. The onset of 4-HO-DMT is really close to flipping a switch (closest to on/off that I've seen with a chemical that is taken orally).
 
Gaian Planes said:
are you sure you didn't mix up samples?

I really don't see how you could find what you found. I think it takes longer because the 4-aco-DMT breaks down into 4-HO-DMT in the body and then crosses the BBB (the difference in effects are a result of the difference in absorption rates).

4-HO-DMT hits within 10 minutes, 4-aco-DMT takes 15-20 and the onset is much more gentle/easy. The onset of 4-HO-DMT is really close to flipping a switch (closest to on/off that I've seen with a chemical that is taken orally).
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I am quite positive I didn't mix up the samples, yes. And I still believe it is just a theory that a 4-AcO-T breaks down into its corresponding 4-HO-T in the body before it crosses the BBB. Is there any proof that the acetoxy cannot cross the BBB itself? And is there any proof that it does convert in the human body? I see two possibilities based on the variation that I and, I seem to recall, at least 1 or 2 others here have experienced from what seems to be the normal set of effects of 4-AcO-DMT in the majority of users:

1 - 4-AcO-DMT (and thus probably any acetoxy ester of a tryptamine) is able to cross the BBB to some extent, and the extent to which it is able depends on an individual's neurochemistry/BBB permeability, and as it sits in the system it converts to the hydroxy at a rate dependent upon the individual. For some people, maybe their BBB won't let it cross at all and it converts slowly into 4-HO-DMT, which is why some people find it almost just like psilocin but slower. For some/most people, perhaps only a little can cross and most is coverted to the hydroxy, which is why most people seem to find its character different from psilocin but still quite close. And then for some, like me, it is able to cross fairly readily so not much would be converted to the hydroxy, and the effects are quite different from those of psilocin. (I find it only passingly similar to psilocin or mushrooms and quite a lot like DMT, although definitely not the same. But it has the same flavor of effects and state of mind to me, and even visual style).

Or

2 - 4-AcO-DMT does not in fact convert in vivo to 4-HO-DMT at all, and it can cross the BBB, but the rate at which it does varies pretty widely. As you know, the volume and speed at which a chemical crosses the BBB can have a profound affect on its subjective effects - think of the difference that snorting vs oral vs IM vs IV can have. There are certainly chemicals in existence that seem to have very different effects between individuals even when taken by the same route of administration... it seems well within the realm of possibility that 4-AcO-DMT and maybe others like it could behave in that way as well.

Or perhaps a third option is true, that it is something between these two.

In any case, I cannot consider my reaction to be a fluke or a faulty observation (like if I had tried each once or twice and gotten different trips and decided what I did). I fully realize that each trip is different. But as you know, when you have many trips under your belt and have tried a substance quite a few times in various circumstances with the intention of making observations as honestly as possible, and you are experienced with psychedelics to the point that you are able to maintain a solid observer state in your mind, you can take note of the aspects of the trip that remain consistent throughout all trials for you. This is especially true of concrete, quantifiable observations such as time of onsert, character of body buzzing, colors and shapes seen, etc. Because of these observations of mine, and because as far as I know, there is no proof that the 4-AcO cannot cross the human BBB or that it necessarily breaks down in the human body, I absolutely believe that there is more going on with 4-AcO-DMT (and indeed the other acetoxy esters I've tried, but most notably this one) than what you assert.

If you have proof or evidence of one or both of those theories (inability to cross the BBB and conversion to 4-HO-DMT), I would love for you to link me to it because I would then have to take that into consideration. But I have never seen such evidence... I have only ever known it as the prevailing theory.

But it's never a good idea, I don't think, to discount or deny the experiences of others unless you feel they have misrepresented their own exprience or do not have a broad enough base of expriences to make any generalizations from.
 
oh I agree with you that these are all just theories. We might never know, but I hope the climate will change so these chemicals can be legitimately researched.
 
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