Opioids Talwin NX (Pentazocine and naloxone) - damage to body?

[STEROIDS4kids]

My psych gave me Dramamine, will that work as a potentiator?

I haven't tried it personally, but i'm sure it will work.

 

[Aeon's Requiem]

Thanks S4K, that may help me take less which seems to be the safest route.

 

[STEROIDS4kids]

Thanks S4K, that may help me take less which seems to be the safest route.

You are very welcome.

PS. I don't think kids should take steroids, i just thought the name would give people interesting reactions. :D

 

[ro0ga]

Sounds like you already are dependent if you're feeling sick when not taking it. I'm not very familiar with exact dosages of Talwin, but when you start taking larger doses of it, it can lead to dysphoria because of its agonist action at the kappa opioid receptor (salvia is a strong kappa agonist). So you might notice that when you take larger doses, that nice euphoric feelings begins to not be quite as "euphoric" anymore.

 

[Aeon's Requiem]

Well, I usually only take two 50mg pills at a time, but I've been taking them every 3-31/2 hours instead of 4 cause it seems to wear off fast. It could be the other crap I take:

60ng prozac in the morning
the sudafed
Occasional excedrin or caffeine pills
Lortabs when I run out of my scrip (7.5)
.25 mg Xanax that I hardly take

 

[Aeon's Requiem]

So, to recap, in the interest of trying to not screw myself up any more than I deem necessary, it's been suggested that I keep my dose lower by using a potentiator such as benadryl or Dramamine, correct? Is there evidence that those work with pentazocine in particular?

I ask this because I'm not wanting to stop at this time, but instead make the most of what I do have.

I'm sorry if I seem repetitive but most of you seem quite knowledgeable on how to reduce physical harm while using a safe, therapeutic, yet enjoyable amount of medication.

Is it possible to increase the bioavailability of pentazocine while getting rid of the naloxone using a different ROA than oral?

Thanks again for the help y'all have already given me. BL kicks ass.

 

[amapola]

Search on google scholar or something to find how pentazocine is metabolized. Then if it is hepatic cyp-450 check out this thread. Awesome CYP-450 Chart!

If it is broken down before hand in the GI then antihistamines will merely aid in the sedation and help with some side effects.