This acquaintance of mine, Sam, had a very low opiate tolerance to hydrocodone (about 30 mg a day for a 3 months). He is kicking the habbit and has some tramadol(50 mg) and kratom(Bali) to take over the next few days. Is there any harm in combining the two? Has anyone had any experience with this? Sam has heard that if you take tramadol first, it could block anything else that binds on opiate receptors (such as kratom). Sam took 150 mg of tramadol about 5 hours ago, and is debating on taking some kratom in fear of drug interactions. Any shared experience/advice/pointers would be greatly appreciated, especially by Sam.
