Kratom blocks EVERY other opioid for me. I was swallowing up to 80mg of hydrocodone a few months back, and it did NOTHING. Zip, zero. Right before that I had a script for tramadol, and kratom blocked that as well.
Not only that, tramadol and kratom just feels like a bad idea. I had a seizure from the tramadol, and for a little while after I came to, I kept getting tremors and really bad brain zaps. Well, fast forward a month or so and I took a kratom extract which did nothing, so I dosed my normal 12-14 grams of Indo on top of it... One of the worst experiences of my life, and during that episode of horrific shaking and anxiety, I got tremors that felt identical to the ones I had post-seizure from the tramadol.
Moral of the story: Idk if kratom alone can cause seizures, and I doubt it can, but what I don’t doubt is that it wasn’t the tramadol alone that caused the seizure (I’d only taken about 300mg over the course of a couple hours), but the combo of tramadol and kratom. I would advise against mixing the two, especially since there’s a good chance it’ll be worthless anyway.