Do you mean could you take it once a week every week without risking a physiological dependence? You can get mentally addicted to a drug regardless of how often you take it, but I think you were taking about physical dependence, where your brain adapts and you need the drug to function normally. Taking it only once a week is certainly far better than taking it every day, but this is actually not a simple question. It's not like if you take it every 4 days for 6 months you're guaranteed to develop a dependence but if you only take it every 5 days for 6 months you will definitely not develop any dependence. Taking it on a regular basis for a long period of time will likely give some level of dependence, even if it is minor and mostly mental. Even if you don't build up enough of a dependence to get severe physical withdrawals upon stopping you may find that your anxiety increases, you get cravings, or you have difficulty enjoying life. You may also find it difficult to stick to the once a week schedule and start taking it more often. Diazepam (and it's active metabolites) has a long half-life and even if you are able to stick to taking it only once a week, if you take it regularly for a long time it can lead to subtle things like tolerance, raising your dose, not feeling able to stop even if it no longer working/you're getting side-effects/your rational mind wants to stop, and getting some symptoms like anxiety if you don't have that pill once a week. But if you are spacing your doses out by about a week there is definitely a lot less likelihood of developing a serious dependence, like where you would risk seizures etc if you stop taking it. Does that make sense?