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Syrian Rue Advice

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ssabusivefw

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Jun 7, 2010
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I've acquired 5-Meo-DMT and have started to experiment with it. My first experiment was with 30mg orally and it was quite pleasant. Very subtle, but nice; brighter colors, euphoria, clearer vision. My next experiment will be with 15mg orally mixed with 3 grams of Syrian Rue. I've read that this can be quite near smoking, but because it comes on somewhat slower it leaves more time to help integrate the experience. However I've always been nervous about MAOIs, but I didn't realize that there was a difference between MAO-A and MAO-B inhibitors.

Thanks to a member on here I was enlightened to this fact, however I need further advice. I've read over the list of things that you aren't supposed to take two weeks before or after MAO-A inhibitors, however Syrian Rue is an MAO-B inhibitor. So I have several questions:

1. Does the same list of restricted ingredients apply to both MAO-A and MAO-B inhibitors?

2. How long should I avoid the restricted items before and after taking the Syrian Rue?

3. Is this time lengthened at the tail end because it is being mixed with 5-MeO-DMT? E.G.: If you should avoid the restricted ingredients one hour before and after taking Syrian Rue by itself, you should avoid the restricted ingredients two hours before and after (or one hour before and two hours after) taking Syrian Rue with 5-MeO-DMT?

4. Can someone naturally be sensitive to Syrian Rue and therefore should I experiment with Syrian Rue by itself before trying to mix it with 5-MeO-DMT?

5. Are there any known cross-sensitivities with Syrian Rue? For example if someone is allergic to Penicillin they may be allergic to Syrian Rue.

These are my main questions/concerns, but any other advice, suggestions, or information would be greatly appreciated. I'm not new to research chemicals, or drugs in general for that matter. However, like I said before, MAOIs have always made me nervous. 5-MeO-DMT scares the shit out of me (and I think rightly so), which is why some of these questions may seem to some to be somewhat pointless but knowing the answers to these questions will put me at ease which will make the experience easier for me. Thanks in advance for any help in this matter.
 
I've read the entire thread but I think the problem there was the fact that he took 5g of Syrian Rue with 30mg of 5-MeO. That amount of 5-MeO is active without a MAOI. Plus he also took almost double the amount of Syrian Rue I was planning on taking. Nevertheless this has made me question this combination and will definitely cause me to do even more research. Thanks for the information.
 
I know there are lots of warning about mixing syrian rue with 5-meo-dmt, but here's somethign right out of tihkal

(with 80 mg harmaline, 10 mg 5-MeO-DMT) "This was conceptually very active. Extremely rewarding. Remarkable difference from the harmaline alone, or the tryptamine alone, neither of which would have been active taken this way, orally."

take it for what it's worth....seems like there is SOMETHING here, even if it is a risky path.

People do manage to explore it and have rewardign experiences...is it worth the possible risks though...I don't know about that. I don't think I woudl do it....

I am VERY curious to try some oral 5-meo-DMT though.
 
If i were going to undertake such a thing, i probably wouldn't jump right in with 15mg of 5-MeO-DMT, probably start somewhere between 5-10mg. You can always take more if you desire, or wait til another trip to increase dosage. Can't really un-take it once things have gotten underway though.
 
3g Syrian Rue + 10mg 5-meo-dmt was enough for a very intense experience for me.

Rue's MAO inhibition is limited and short term... I would not worry about long-term combinations causing any problems, just immediate ones like no stimulants, avoid cheese & beer and other things with tyramine within 1/2 day or so of doing the Rue... the effects wear off fairly quick, within a few hours your MEO is back to normal really.
 
Chemical Wizard said:
I am VERY curious to try some oral 5-meo-DMT though.
Click to expand...

BTW thanks Dwayne for the advice on taking the 5-MeO-DMT orally without an MAOI. It worked beautifully and I found quite it interesting at 30mg (as subtle as it was).

Based on the TIHKAL, maybe I will take about half of that. The Syrian Rue I got states that it (supposedly) contains about 2% mixed Harmala alkaloids. So maybe I will drop the Syrian Rue dose down to 2g (~40mg Harmala alkaloids), and drop the 5-MeO-DMT down to 5mg. If nothing then I would try upping the 5-MeO-DMT to 10mg on another day. I think this is a logical and reasonable idea, and at this level I would probably avoid any possible negative reactions from the combination.
 
if you have never tried syrian rue before, be aware that it is not simply an MAOI. depending on your individual body chemistry, 3g of rue may be an emotional tripping experience in itself.

speaking as someone who thought that "rue+shrooms" would just make "shroomsx2" (it does not), i would say try 3g of rue on its own and see what kind of effects it has before you add any 5-meo-DMT.
 
Oh yes, not just an amplifier. I thought Rue made shrooms feel calmer, more focused, more "spiritual"... it seemed like there was some sort of "guardian spirit" there in the room with me the whole time.

So greenmeanies, you neglected to say what rue+shrooms was like for you, would be interesting to hear.

And I agree, rue all by itself can be a pretty interesting trip... and it also makes pot seem alot deeper as well. Very interesting tool.
 
i've gone on in detail in other threads. suffice to say it was only my 3rd time with shrooms, and it was an unweighed dry handful of end-season (tiny fuckers) ps. cyanescens... i'd estimate i was zero to +++++ in about 16 minutes flat. in the next few hours i died, went to hell, tried to escape, died, spoke to god (who was me), condemned myself back to hell again, spoke to the devil (me again), and finally closed the book on my pitiful existence. it was quite the traumatic spiritual awakening.

as far as set and setting went, i was raised christian but had fallen away in college. i also have one asian-american immigrant parent. it was fall quarter, my third year at university. the biggest emotions during the trip were: joy that i was given the gift of life; euphoria that i was taking part in the great eternal mystery; guilt that i was unworthy of such a journey; fear that i had let down my parents; curiosity at what lay beyond the fear...

for some reason i made the mistake of taking rue+shrooms AGAIN within a couple weeks of that first bad trip, and i was catapulted directly through the same roller-coaster. but the end of the second trip actually gave me more closure and i was able to move on and integrate. unfortunately my first experience with LSD (two whole years after the bad shroom trip) gave me some kind of negative vibe, but i'm too busy exploring the world of phens to be troubled. :)
 
Well I guess measuring dose carefully is a good idea, maybe? haha. I dont understand what people are thinking when they KNOW full well they are doing an extremely potent mind-bending psychedelic, but think "Oh well what the hell I'll do this amplifier first then just grab a random HANDFUL of the shrooms and hope for the best." I think you really KNEW subconsciously what the excessive result would be, and WANTED/NEEDED that sort of a cathartic experience, and the cavalier attitude was a way to get yourself to do it and not chicken out." Either that or it was just a vacuous dumb impulse, and you should have learned from the mistake.

Yes, with 3g rue, 1.5g dried shrooms = strength of 3g without rue PLUS added depth and intensity. 1.5g is a really SMALL volume.

So I can imagine what you went through on a "handfull" was pretty damn intense.
 
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Rue on it's own can make you trip so it might be worth trying it on its own before combining. it was one of my earliest trip and produces a unique experience unlike anything else. It procuded closed eye dream like visions. One was a tunnel with my eye at the end of it. And another was a sweeping shot of some trees. Had nothing like it on shrooms etc. This was all after the projectile vomiting and feeling shite however.:\
 
I must have an iron stomach... 3g of finely powdered rue seed (in a coffee bean grinder) on an empty stomach gave me no nausea. Maybe you ate them whole? Yea it does give you a nice cozy mild otherworldly sort of trip feeling on its own, quite nice, like your head is wrapped in a warm electric blanket and then some, one can really see why the ancients considered it a revered ally in its own right, as well as a good modifier of other substances.
 
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