i tried that myself a few weeks ago, it would get over powered by the synths. it has pros and cons. when the peak from the synths wears off you'll still be a little high from the actual stuff. tho i might as well have just smoked synths alone.
i ended up mixing the tokes, one bowl of real stuff, then later one bowl of synths etc, u get to enjoy both.
just be ready to know that after u smoked the snyths your tolerance for the regular stuff is gona rise high and take some time to normalize, just thought i would add that in there since its your first time using synths.
if u want to enjoy MJ smoke it separate otherwise when you mix it you wont notice the MJ till the synths wear off.