Opioids Synerg opioids/opiates

[Coffeeshroom]

Are There any opiods/opiates that you can use together that has a synergy effect.

More so looking at methadone. Is there any one of them you can use with methadone that will have a synergy effect and make you feel it harder or is methadone just to strong at competing for receptor sites and not make anything else have a synergy effect with it, let alone throw you in precip wds

 

[Jabberwocky]

I would say kratom meshes well with other opioids, but it's also not really worth it because it increases tolerance.