[supplements] WIP 'simple' guide

[harm_reducer]

First off as a new user of both this site and drugs in general I want to thank the admins and users for making all this information available. In the Directory I found this article on preventative / restorative dosing which is really helpful but I don't understand exactly how to put into practice the things it suggests. When do you take the supplements? Which ones are especially important if I want to make this simple?

anyway heres the cited thread: http://www.bluelight.ru/vb/showthread.php?s=&threadid=407429

Ok So in my quest for simplicity i am gonna try to come up with three cocktails, one antioxidants for preventing axon damage, one with 5-htp for post-E neurotransmitter replenishing, and one to help deal with side effects of E .

OPTIMIZING THE ACUTE EFFECTS OF MDMA

5. Magnesium
Description: Reduces tolerance, Reduces jaw clenching whilst on MDMA and a overall muscle relaxant

Dosage: Everyday, 400mg

Note: Take chelate form of magnesium, none of the bullshit Oxide and other forms, they have terrible bio-availability.

my questions:
Do you have to take it constantly to reap the benefits? How long before E do you have to be taking it ? Could you take it with mdma?

6. Piracetam
Description: Another must get supplement, Modulates Serotonin and dopamine receptors, Enhances neurotransmission, Anti Oxidant, and also potentiates all stimulants. Makes your peak feel more clean

Dosage: 3200mg before stimulant and after

my questions:
What does "before stimulant usage" mean? is it acceptable to take at the same time as MDMA? some number of hours or days before?


MINIMIZING BRAIN DAMAGE

Quercetin
Description: inhibits enzyme CYP3A4, one a few enzymes responsible for the breakdown of MDMA, therefore potentiates MDMA. It exerts potent antioxidant activity and vitamin C-sparing action.
COMT Inhibitor
MAO-B Inhibitor

Dosage: One capsule, take with Vitamin C and/or with other antioxidants

my questions:
When do you take it? same time as mdma?
How much is one capsule?
Potentiates MDMA- does that mean it keeps the mdma around longer? similar effect as redosing?

Green Tea extracts (EGCG)
Description: Another MUST GET supplement, VERY POWERFUL antioxidant, 200x more than Vitamin E. COMT Inhibitor which is one of the many enzymes responsible for the breakdown of MDMA. It is also a Decarboxylase inhibitor so it potentiates 5-htp and l-dopa

Dosage: Take with 5-htp so that 5-htp gets converted to serotonin in the brain and not in your gut, also before MDMA usage for potentiation and powerful antioxidant activity. Dose: 300mg of 40% EGCG extract

Can the pre-mdma dose be taken at the same time as the mdma? if not, how long before?

Vitamin C
Description: Anti oxidant

Dosage: 3000mg pre stimulant, 2000mg x 4 the next day. Take with EGCG and other anti oxidant

Q: pre stimulant approximately equal to same time as stimulant?

10. Deprenyl (Selegiline)
Description: MAO-B inhibitor, not to be mistaken with ordinary MAOI's. it reduces cardiovascular toxicity, inhibits formation of peroxides in the brain. inhibits Dopamine metabolism. it may revive dead neurons in the brain. it may reverse neurotoxicity. It is even said it inhibits neurotoxicity from METH use.

Dosage: 2.5mg with food 1 hour before MDMA usage

11. Taurine
Description: General cellular health supplement, its a amino acid as well as a neuromodulator. Its a neuroprotector and regulates Calcium ions in the brain. its also a great anti-anxiety agent

Dosage: 1500mg before food a day

Q: is this taken every day? a day before mdma is taken? How long / often does it need to be taken before mdma to work properly?

L-Theanine
Description: Glutamate receptor antagonist (AMPA, Kainate, NMDA), Dopamine releaser, Enhances focus, mood, and memory. reduces anxiety and nervousness

Dosage: 200mg per dose. good relaxant post mdma usage and pre

Q: How long does it last? when do you take it? is one dose at the same time as mdma acceptable?

Acetyl-L-Carnitine Arginate
Description: NGF agent (nerve growth factor) stimulates the growth of neurites in the brain. it MAY reverse neurotoxicity and protect the brain from peroxynitrites (very potent neurotoxin that causes harsh oxidative stress)

Dosage: 2000mg a day of Ordinary Acetyl-l-Carnitine, or 800mg of Arginate form. its a good idea to have a combination of both as they work together

Note: Arginate is fairly expensive but it is a lot more potent and beneficial, otherwise you can just get the normal Acetyl-L-Carnitine

Q: Do you have to take them daily? when do you need to take them for them to be effective?




REPLENISHING SEROTONIN AND DOPAMINE

Green Tea extracts (EGCG)
Description: Another MUST GET supplement, VERY POWERFUL antioxidant, 200x more than Vitamin E. COMT Inhibitor which is one of the many enzymes responsible for the breakdown of MDMA. It is also a Decarboxylase inhibitor so it potentiates 5-htp and l-dopa

Dosage: Take with 5-htp so that 5-htp gets converted to serotonin in the brain and not in your gut, also before MDMA usage for potentiation and powerful antioxidant activity. Dose: 300mg of 40% EGCG extract

5-HTP
Description: Precursor to Serotonin, increases serotonin levels

Dosage: 100mg x 3 post MDMA usage. Do not take it for more than 5 days in a row without dopamine precursors; otherwise it will cause depletion of dopamine – take with Green Tea

Q: when would you take your first 5-htp dose? same time as mdma? 1 day after mdma?

14. L-Dopa
Description: like 5-htp, its a direct precursor to Dopamine, a lot better than tyrosine.

Dosage: Take in morning before food with Green Tea, 200mg. its a good idea if your taking 5-htp at night to have this the following morning for optimal neurotransmitter levels.

Note: DO NOT TAKE for atleast 24 hours after MDMA usage as the excess dopamine may get trapped by SERTS that have been activated by MDMA and cause oxidative stress.

Q: Why the 5-htp at night, l-dopa in the morning before food? What if you take them together 24+ hours after mdma?

Tianeptine (Selective Serotonin Reuptake Enchancer)
Description: a very unique Anti depressant that works opposite to SSRI's, instead of inhibiting the uptake of serotonin back to the pre-synapse it enhances it. meaning it increases your overall serotonin storage rather than aiding its depletion that SSRI's do...

Dosage: recommended 12.5mg 3x a day.
Note: this will probably work better than anything to increase your "true" serotonin levels long term and restore them to optimal levels. this is the most worth while drug to take but its prescription only. apparently its legal to import without.

Q: when do you need to take it for it to be effective?

Ginkgo
Description: Days after MDMA usage, elevated levels of MAO activity in the brain are present, this further causes depletion of Serotonin and also Noradrenaline, thus lethargy and loss of motivation,

Ginkgo works as mild MAO Inhibitor as well as increases blood flow to the brain

Dosage: 200mg x 2 daily Post MDMA anf following days

COCKTAILS CHRONOLOGICALLY

This is the part that I am unsure about and I am asking for the most help in organizing.

Don't take these as instructions BY ANY MEASURE they are just guesswork based on other things I've read on this site.

Which of these drugs could be cut out ? which are the crucial ones, and what are the crucial details about how they are taken?

How do the dosages interact? are the mentioned dosages for when you are taking only a few of these things, or for when you are taking all of them?

What are some common pitfalls when doing this kind of thing?

Who was this designed for? first time users? people who pop 10 pills in a weekend because they don't understand how the drug works? "responsible" users, who take it no more than once a month and take 3+ month breaks?

pre-dosing... for 1-3 days before taking MDMA? more?
- - - - Taurine, 1500mg before food
- - - - take 400 mg per day of "the chelate form of magnesium"

T: -1 or -6 hours? help?
- - - - 3 grams Piracetam
- - - - 300mg of 40% EGCG extract (green tea extracts)
- - - - Deprenyl, 2.5mg with food

zero-hour "be careful - you are taking a very big drug!"
- - - - 80-120 mg MDMA
- - - - One capsule Quercetin
- - - - 3 grams Piracetam
- - - - 300mg of 40% EGCG extract (green tea extracts)
- - - - 200mg L-Theanine
- - - - 2000mg a day of Ordinary Acetyl-l-Carnitine, or 800mg of Arginate form

post-dosing... for 1-3 days after taking mdma? more?
- - - - IMPORTANT NOTE: DON'T TAKE L-DOPA UNTIL MORE THAN 24 HOURS AFTER MDMA - dopamine + mdma = neurotoxicity.
- - - - For the same reason why MDMA + Meth is really bad
- - - - 2000mg a day of Ordinary Acetyl-l-Carnitine, or 800mg of Arginate form (optimal is a half dose of each, they interact well)
- - - - 300mg of 40% EGCG extract (green tea extracts)
- - - - 100mg 5-HTP
- - - - 200mg L-Dopa
- - - - 12mg Tianeptine 3x a day
- - - - 200 mg Ginko 2x a day