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Bupe Suboxone separation/extraction

citizenuzi

Bluelighter
Joined
Apr 4, 2006
Messages
215
Location
Western Mass
In using suboxones, I'm wondering if perhaps there is a simple way to reduce the pill matter. Perhaps as simple as dissolving in water, filtering and then drying to form crystals (I hope!).

Better though would be an extraction of the buprenorphine from the naloxone.

Any chemists or brainiacs care to help??
 
It's not going to work from the best of my knowledge. Both chemicals are soluable in the same liquids.
 
biggerstronger said:
It's not going to work from the best of my knowledge. Both chemicals are soluable in the same liquids.

thats the key. finding something that naloxone dissolves in that buprenorphine doesn't. or vice versa. I talked to someone through private message who began giving me advice on how to separate the two, but I seem to have deleted it. Or maybe the pharmaceutical companies saw this one coming and purposely made it a bitch to separate the two.

someone out there knows how to do it. i'd look a little harder but i got off suboxone like 2 weeks ago (so i don't really care, and still don't feel completely 'normal').
if people keep bumping this thread eventually someone will have some better advice. :\
 
Why bother extracting the naloxone? If you are addicted to bupe only which will happen in 7-10 days you can inject that crap if you want without the naloxone really affecting the action of bupe due to the extremely tight receptor binding of bupe which is higher than naloxone's. However, injecting pills is extremely dangerous and people loose limbs doing this. Finding pure bupe ampules would be the safest practice. Unless you have a chemistry degree I doubt you'll be able to get the two seperated. Check to see what each are soluable in and the best way to extract the two minus fillers and naloxone. I say it's close to impossible for almost every one on this board except those with advanced lab experience even then I have my doubts.
 
No need to extract the Naloxone, the Buprenorphine blocks its effects anyway.....

I did an extraction once on my Subutex to reduce pill matter; I just dissolved a few tabs in water, filtered, let it evaporate, I was left with approx. half the pill matter I started with....
 
umm, 1# suboxone has a half life of 72hours and number two, PLEASE dont be stupid enough to try shooting suboxone. thats horrendous, the narloxone is in there partly for the purpose of stopping people from trying that. Not to mention its designed to make you sick if you try to get a rush from it. But dont take my word for it, see for yourself.
 
It would be eaiser to get some Subutex, then it would be to extract the bupe from the nalexone. imo
 
TTZ234 said:
I am addicted to bupe mainly and I use too shoot up the subuTEX tabs.. i tried to shoot subuxone once what many people in my town does quite sucsessfully they claim..it did'nt work at ALL after that I'v IV'd some 2mg subutex cuz i were pissed and THEY didnt work either..still sick i bought one bag of dope an that worked as a bitch..got me high and WELL!.but I don't like taking dope anymore makes me feel guilty..Aint this supposed to be an impossibillity??

If it made you sick then you weren't just addicted to the bupe or you are unusually sensitive to naloxone. Honestly though I think you weren't fully dependent on only bupe. If you take the suboxone for awhile even shooting bupe/naloxone wont effect anything besides the obvious risk of injecting pills which is pointless and dangerous in the case of suboxone and most other pills for that matter.
 
I know a lot of people here say that the naloxone in bupe is inactive when shot, but I have definatley had adverse reactions on more than a couple occasions shooting bupe. Usually when shooting larger doses of it. However, these negative reactions generally lasted between 15-45 minutes or so, and I did shoot quite a bit of suboxone with great sucess. It is possible that these negative effects were a result of precipitated withdrawl(can't really remember), but it seems like the higher doses of bupe would treat me bad no matter what. So, when shooting bupe will the naloxone have no effect no matter what? Or only in smaller doses?
 
In Germany we got Tilidin combined with Naloxon. Many guys tried or thought about how to remove the ugly naloxon...
There is a way that could work: Naloxon is very instable for UV and hot temperature... So, maybe this could be the right method...

Remember: Naloxon has a half-life of about 60 minutes, so lower doses are not working for a long time... This could be the reason why it "works" to shoot smaller amounts (but not really, you maybe just think so...).


Tramadol0r
 
Bupe isnt like most drugs for the fact if you double the dose you wont double positive effects, youll actually diminish them. Kind of like after you smoke like a G of hydro nugs if you smoke 2 Gs you wont get much higher at all.

Suboxone in say 2-4mgs will produce a noticeable(some people more so then others) energetic euphoria. In doses like say 8mgs because the drug works on blocking certain receptors(mainly dopemead) and due to the excess amount of receptor blockers running around your brain with nothing to do in the higher doses they begins to block the other certain rectors that are causing the euphoric energetic buzz in lower doses! Sorry if this doesnt help, this was the best i could explain it while keeping it simple..
 
asfter blasting suboxone, how long for it to take effect? and do u have to shoot the benadryl or can u judt pop a couple a little while befoe shootng sub?
 
Bupe isnt like most drugs for the fact if you double the dose you wont double positive effects, youll actually diminish them. Kind of like after you smoke like a G of hydro nugs if you smoke 2 Gs you wont get much higher at all.

Suboxone in say 2-4mgs will produce a noticeable(some people more so then others) energetic euphoria. In doses like say 8mgs because the drug works on blocking certain receptors(mainly dopemead) and due to the excess amount of receptor blockers running around your brain with nothing to do in the higher doses they begins to block the other certain rectors that are causing the euphoric energetic buzz in lower doses! Sorry if this doesnt help, this was the best i could explain it while keeping it simple..

-472 for being one of the dumbest posts ever...

please don't post if you have NO CLUE what you are talking about... please

first off, smoking G's of hydro nugs doesn't much compare to this, and with pot, some people do keep getting high, in fact most people do, until they get so high they pass out or they puke (done both, so its from experience). secondly, 8mg is not that high of a dose of bupe, esp when taken as suboxone and by someone who takes it regularly. also, bupe does NOT work by "blocking the dopemead" receptor... there is no dopemead receptor. are you talking about dopamine? it doesn't block that either. bupe is a partial agonist of mu-opiate, and afaik an antagonist of k-opiate (and possibly slightly agonist of delta, but not sure here) receptors. that means that it "partially activates" the mu receptor (and possibly the d) (this is "keeping it simple, just for you") but does not "block the receptor. if you take it after taking heroin, for example, it has a higher affinity for the receptors, so it will "knock" the heroin out, but it doesn't activate the receptors as much, due to its partial agonist abilities, so you actually can induce withdrawels in people that are opiate tolerant, to full agonist opiates. if you are not tolerance at all, then it activates the receptors and gets you "high" (or gives you opiate effects, although slightly different because even though it is working at the mu receptors, every drug acts slightly diff, plus its only a partial agonist). the naloxone only works when injected anyways, but they didn't think muchwhen they put it in the suboxone, because bupe has a higher (much higher) affinity for the receptors than naloxone, so even if you inject it, the bupe goes tot he receptors and locks itself in there and won't let the naloxone in. even if you injected with straight naloxone while on bupe, yo uwould likely feel nothing (whereas if you were high on dope and did that you'd be sick as shit)
 
OK CLOSE THESE STOOPID POSTs. We all know suboxone and subutex are the same, naloxone isnt even absorbed sublingually.
 
Sorry for all you who are forced to take artificial sweeteners with your bupe, but honestly naloxone does not do ANYTHING. I have friends that will probably die or loose their arms that shoot suboxone EVERY DAY and GET HIGH. Luckily I am prescribed subutex, simply because the fake sweeteners in suboxone were making me sick (and are carcinogenic, mention that to your idiot doctor) so I simply want to know how to extract the bupe from the FILLERS and end up with a smaller pill, to snort. I hate IV'ing....needles are gross, dangerous, and make my arms sore every time I inject, not to mention track marks are anything but attractive..sooo---does anyone know how to remove all or some (any amount would be nice) of the filler without removing the buprenorphine?
 
^ what I do to make large amounts of pill powdereasy to snort is to prep it like your doing a shot, with about 2mls of water, filter, then spray it in your nostril and hold it closed. This is how most drugs are delivered intranasaly anyways, not with dry powder.

But if you want a smaller for of powder I'm sure you could evaporate it or something.
 
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