OxyDillyKing
Bluelighter
Everyone seems to have a different opinion about how Subs actually work. the consensus about the Naloxone on bluelight is that its basically inactive, even when injected, and i pretty much believe this cuz its seems people are shooting them all the time now without going into WDs. i have been perscribed to them for over 18 months and have never tried it and probably never will. my question in regard to how the bupe works with other opiates. it seems in the context of taking Subs too soon after doing other opiates what is at risk is going into WDs. But is the context of taking other opiates too soon after doing Subs, all that is at risk is not feeling the shot. Is this right?
It seems when people are asking when its safe to do a sub they are worried about getting the precipitated WDs from the bupe knocking all the other opiates out of the receptors in brain.
It seems all people are worried about when ask when it is safe to get high again after Subs is will they feel it or not, they dont seem concernec about it causing WDs this way.
Does have something to do with the fact that bupe has a higher affinity that other opiates for binding to receptors, in other words its good at binding, so it can kick the other opiates out if you are doing a Sub after other opiates, but because it holds on so tightly, if you do another opiate after a Sub, the other opiate isnt good enough at binding to receptors to kick the Sub out?
Also another question that is semi related, why do you into WDs from taking sub to soon? i understand its the bupe that causes this since compared to other opiates it has a higher affinity for bind to receptors, and it knocks the other opiates out of your receptors, but if the bupe has knocked them out and binded it self, why isnt it just the bupe keeping you well after it has knocked the heroin of oxy of for example? is it because the bupe doesnt bind, it just tries to and because its so powerful at binding it ends up knocking the other opiate off the receptor, but the bupe itself also doesnt get a chance to bind cuz the receptor " parking spot " was not empty when it tried to enter?
It seems when people are asking when its safe to do a sub they are worried about getting the precipitated WDs from the bupe knocking all the other opiates out of the receptors in brain.
It seems all people are worried about when ask when it is safe to get high again after Subs is will they feel it or not, they dont seem concernec about it causing WDs this way.
Does have something to do with the fact that bupe has a higher affinity that other opiates for binding to receptors, in other words its good at binding, so it can kick the other opiates out if you are doing a Sub after other opiates, but because it holds on so tightly, if you do another opiate after a Sub, the other opiate isnt good enough at binding to receptors to kick the Sub out?
Also another question that is semi related, why do you into WDs from taking sub to soon? i understand its the bupe that causes this since compared to other opiates it has a higher affinity for bind to receptors, and it knocks the other opiates out of your receptors, but if the bupe has knocked them out and binded it self, why isnt it just the bupe keeping you well after it has knocked the heroin of oxy of for example? is it because the bupe doesnt bind, it just tries to and because its so powerful at binding it ends up knocking the other opiate off the receptor, but the bupe itself also doesnt get a chance to bind cuz the receptor " parking spot " was not empty when it tried to enter?
