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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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Hi Forum,

Regular forum junkie from last year. Glad to see this place is alive and kicking.

What am I my self at? Well, for starters, currently on 3.6mg of Subutex. But, no longer holding me 24 hours but only twelve. I withdraw every night now. So, I decided to invest in some methadone. Got 100ml today.

My problem is thusly; I just swallowed 10millilitres of methadone and felt quite nauseous! And all the opiate conversions charts are saying 20-30mg of methadone are similar to 0.5 to 1mg of Subutex.

This means, at most, if I make the switch I'll be on 150mg's of Methadone daily.

But, what is that in ml's? I don't understand that gram stuff for methadone. Most my buddies are on 50ml's and they say that holds them well and some days they can skip a day.

I've heard of people taking upwards of 400ml's tho for maintenance.

So, being on 3.6mg of Subutex in my system already, which lasts approx 12 hours tops before I hit a wall, when I do hit the wall how many ml's of methadone (liquid (green)) do I take?

It tastes MUCH BETTER than Subutex!!! Haha.

I dunno if this is the right forum to ask ~ please move if required to somewhere where people can answer this question.

I kinda need to know within the next 10 hours if possible before my first dose.

Thank you in advance for any help or advice you can offer me.

Kind regards,

CC
 
^You need to know the concentration of the liquid methadone you are being given. There is a certain number of mg per ml, usually 5-10 mg/ ml but that seems a bit high here... 1mg/ ml makes more sense how you are describing it, you'll have to find the name of the stuff you're taking to know for sure, though.
 
Hi Pegasus,

It is 1mg/ml like you said. And I got 100ml. So far, I've had a couple of sips, and it held me for a few hours, then I went into a small chill.

So, I've just this minute taken another sip. And feel a lot better. Roughly, I'd say I've so far, over the course of the day, taken 10ml.

I am too scared to take a large amount in case I mess up and vomit.

So, thanks for the help, but I've decided to take little sips throughout the day and night to starve off any w/d symptoms. But, what I want to know now, is should I wait until into w/d to take my morning Subutex? Weird situation I know, but I've been taking subutex for a long time, and its just not holding me anymore.

Whereas, this tiny amount of Methadone, well, really sorted me out for a while.
 
Methadone is a very long lasting full agonist. You'll need to wait several days after coming off it before taking buprenorphine or risk precipitated withdrawal.
 
OK, so my previous post was probably a bit much as far as asking for advice. In short, I guess what I should have asked is how many people are on maintenance. My dilemma right now is deciding whether to stay with my doctor and taper off (which is all she can legally do at this point) or find another doctor and stay on maintenance. It's really helping me, as it alleviates my Crohn's symptoms and helps me sleep (otherwise, I'll need some kind of sleep aid, most of which I hate).

Ultimately, my biggest fear is that one day something will happen (such as losing my job) and I'll no longer be able to afford/acquire Suboxone. If that happens, I won't have the option of tapering. Right now, it is an option, but it's not really what I want to do, knowing how shitty I'll feel without it.
 
amapola said:
Methadone is a very long lasting full agonist. You'll need to wait several days after coming off it before taking buprenorphine or risk precipitated withdrawal.
Click to expand...

Ouch. That is not what I wanted to hear :(

I'm on daily supervised collections of Subutex you see. And basically, if I miss a few days due to this methadone, I'll basically require re=scripting.

I hear you too about this methadone being long lasting. I remain in a good way even after almost 12 hours since my last sip of the stuff.

Perhaps this is a good time to decide some stuff right here. Like, calling my drug worker for an immediate appointment etc...to tell him I want to go onto Methadone script? Because, I feel real tired right now. And I can do without any precipitated withdrawals.

Maybe too, Methadone is easier to stop than Subutex? Or perhaps they're both the same in terms of addiction. Oh, dang, the choices, eh? Well, I have until 8am to decide...
 
in my experience, methadone seems to be harder to stop than subutex because it acts as a full agonist, giving a more potent/pleasurable experience. when on MMT, the first month was amazing, and after that I was still able to get "high" for a couple hours after initially dosing or doubling up on the weekends with take-homes. with subutex you might get a high from your first 3-4 doses, but after that, I have felt nothing short of normal.

I guess what I'm trying to say is subutex just keeps my withdrawal at bay, while keeping my cravings down (because it is physically impossible to get high on other opiates while on subutex maintenance), whereas methadone gives me a more classic opiate feeling, including muscle relaxation, slight euphoria, and general lethargy, and if at a dose around 60mg or lower, it is still possible to use other opiates and feel them, quite well.

That's not to say someone on less than 1mg of subutex couldn't get high, but the point I'm making is I believe subutex to work a lot better as a maintenance drug because it allows the user to experience a taste life without opiates, and once the cravings are completely gone, and the user decides to stop them, it's an easier transition.
 
You know...its amazing how different people's metabolisms are.

I've been on 16mg/day of Suboxone for about 7 straight weeks. I decided to take a little break from sub and use again for a couple week binder. Well after about 24 hrs of not taking any sub, I felt minor WD symptoms and since that's the general rule of thumb to be able to feel opiates again, I took a dose of oxycodone that was 1/5 larger than I would normally take before I got on sub. Well much to my surprise I felt roughly 75% of the dose, and nodded out pretty damn hard while feeling that wonderful warmth.

Now I'm not bragging or anything like that, and I plan to get back on subs soon at a much lower dose this time (I originally took a break b/c of the side effects, like sleeping for 12 hrs a night yet being lethargic all day, not to mention problems keeping Jr. up). My question is: are there other people reading this that can also switch back to an opiate/oid quickly after being on subs for a while? And is it JUST because of metabolism or are there other factors?
 
tom80 said:
You know...its amazing how different people's metabolisms are.

I've been on 16mg/day of Suboxone for about 7 straight weeks. I decided to take a little break from sub and use again for a couple week binder. Well after about 24 hrs of not taking any sub, I felt minor WD symptoms and since that's the general rule of thumb to be able to feel opiates again, I took a dose of oxycodone that was 1/5 larger than I would normally take before I got on sub. Well much to my surprise I felt roughly 75% of the dose, and nodded out pretty damn hard while feeling that wonderful warmth.

Now I'm not bragging or anything like that, and I plan to get back on subs soon at a much lower dose this time (I originally took a break b/c of the side effects, like sleeping for 12 hrs a night yet being lethargic all day, not to mention problems keeping Jr. up). My question is: are there other people reading this that can also switch back to an opiate/oid quickly after being on subs for a while? And is it JUST because of metabolism or are there other factors?
Click to expand...

It's because buprenorphine wasn't covering 100% of your mu-opioid receptors; the ones left open were effected by the drugs you took. :)
 
Is bupe raising my tolerance or

I have been on 16mgs of bupe a day for almost a year and have recently quit for almost 7 days (since 11 on sunday) for a very painful oral extraction that happened about 4 days ago. I have been taking prescribed oxycodone for 4 days now and found it hardly works the same way when I haven't had any other real opiates since I started subs and took a dose that would usually knock me on my ass before I started just to be able to eat.

Is there still a chance that my metabolism is slow and that 1mg is screwing it up? I am getting refilled today (monday morning) but need to know whether to wait, upgrade from the 7.5s to the 10s with the doctor or just wait? I am in a lot of pain and want to avoid raising my sub dose as a substitute because I fall asleep and cannot function when the dose it raised.

It it tolerance or leftover bupe?
 
Hi there, newbie here, I've read about 40 pages of an older buprenorphine mega thread and can't quite find what I'm looking for. I've been using 200mg of codeine a day for about 7 years now. I've tried tapering but can't handle the WD (bit of a sissy). I don't use to get a buzz, I do it to keep the WDs away.

So, in 60 hours I'm starting a suboxone program. But after what I've read here that seems like overkill. I mean, I've never injected, I don't drink, and other than pot I don't smoke. But codeine is getting hard to come by in my country, and I'm sick of lying to chemists every day.

Please help, I know I'm small fry but I'm shitting my pants!
 
tylerwashere said:
My doctor has always given me the regular suboxone, orange, nasty ass tablets. 2 weeks ago he gave me something new. Suboxone strips. They are like those listerine strips that yoiu put on your tongue and it slowly dissolves. I haven't tried em yet, i've had enough orange tablets, but this seems kind of weird. Anyone else try these? My doc said its exactly the same...
Click to expand...

Ah yes, I personally requested these from my doctor, they dissolve and absorb so much quicker and better than the tablets, less filler, more killer haha but I honestly love them over the tablets because theyre quicker to take and I dont have to hold that bullshit in my mouth for 45-60 minutes just to get the full effect:)
 
Hi Forum,

Just like to state that I took my Subutex dose (3.6mg) at 10.30am with no pwd whatsoever.

Quite pleased with it too since yesterday I triple dosed methadone.

Someone on here said I'd have to wait 3 days before taking Subutex again. That was incorrect.

Not sure why they said that. Perhaps because of the old knowledge that being on Methadone and changing over to Subutex, it is best to wait.

But, just so you know...you can take Subutex regularly, and sip the odd methadone every now and again to catch a real nice effect.

Peace out and love in.
 
^I would say you got fairly lucky with the level of your doses and wouldn't recommend you make the general statement "you can take Subutex regularly, and sip the odd methadone every now and again to catch a real nice effect" without some major disclaimers.

People on a high dose of buprenorphine will have methadone do almost nothing for them, and people on lower doses risk precipitated withdrawal. The fact that the methadone really helped you feel good means that a fair amount of it attached to your receptors (your bupe being low enough in your system at the time to allow this). Taking a large enough dose of bupe only a day later would indeed have ripped the remaining methadone (over 50% of it due to the long half-life) causing precipitated withdrawal. Apparently in your situation you had a low enough dose that the competitive bupe didn't effect the overall levels of opioids that much.

This could in fact differ for people on the exact same dose as you, and surely could for people with different doses.
 
it baffles me how little doctors know sometimes. Yesterday my girlfriend said there was a chick she went to rehab with who was prescribed a couple milligrams of bupe for pain when she had no opiate tolerance. so A) she was fucked up and nodding all day feeling like shit - and B) micrograms, not milligrams, would have been the correct dosage range in this case. With the correct dose she would have had better analgesia and avoided the side effects.

Fuckin' doctors... They seriously don't know shit when it comes to bupe at least.
 
So I posted this in the film thread, but I figure it belongs here since I take the tablet.

I've read using alcohol with the sub makes it work better sublingually. BUT whenever I do that, OR just take it by itself sublingually I always build up so much saliva and I don't want to swallow it because im sure htere is a lot of bupe in there that hasn't abosrbed. So i keep like half mouthful of saliva swishing it around my mout hfor like 10 minutes. Its really annoying, anyone know a way to help fix this? I hate having a shit load of saliva in my mouth that I have to keep in for 10 mintues hah

I also take the pill/ or crush it, and spread it around my mouth, under tongue, in gums, and cheeks. I read that more surface area = better BA . right?

But either way I build up so much saliva I find it rather annoying
 
Quick question, I've withdrawn and hopped back on suboxone and diaC, oxy, ect many times, and I've been taking 4mg's of suboxone, 2 times a day for the past few weeks, currently my last dose of bupe was yesterday morning at 8 a.m. Its now 3:37pm and I've seen my body do the usual signs, first my nose was running profusely this morning, and still is, my bodys aching, goosebumps at every slight breeze outside or temperature change going in or outside, irritability, ect. Also I've tested my pupils in a pitch-dark bathroom, waiting a minute or so til they adjust and flipping the lights on quickly, which makes them shrink, but definitely no where near pinned like on sub. Question is, what do yall think? Would I be ready to dose a full agonist this evening with effects? I understand the half-life and it is very long, yet I know my body and its w/d symptoms quite well. I'd just appreciate a second or more opinion. Dont wanna waste my goodies :)
 
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