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Bupe Suboxone/Buprenorphine FAQ and Megathread v.1; 2007 - 2010

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ahlongsan said:
thanks once again capt H, i do have a tolerance of benzo so therefore as u have said i should be alright...just one more question please... based on 1x0.216mg per pill sub with alcohol, how many pills should i sub to get a high??? i have not had any CWE codiene for a mth and a half now so i'm not sure if i have any tolerance to opiates?? ii normally chug 150mg of CWE Codiene to get a high so what do u reckon would be a good dose for me??

Cheers, mate
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Well...I am guessing you have a low opiate tolerance. I would try 3 at one time, because this will provide you a dose that is slightly below or above 0.5mg of buprenorphine. This is a standard dose many people feel euphoric from. If you took less than this, it might work but you might not feel it. If you took more, you will get higher, but it is likely you won't need but 3 of the pills.

If 150mg of codeine gets you high...then 0.375mg of buprenorphine is an equipotent dose. This means 2 and 1/2 pills ought to do the same effect. So, my guess of 3 pills was pretty close.

However, codeine and buprenorphine have different effect profiles. So, it's hard to draw an equipotent dose between the two.

I would say, start with 2 and 1/2, maybe 3 pills. You will want to wait a whole day before re-dosing; it won't be as effective if you don't wait to re-dose.

Let us know how it goes.

subisjustokay said:
Okay so I have yet another question... The subs are working great and I've been off the opiates for.... 15 - 20 days I guess... I really don't even know... but I like to take Alprazolam at night (I have the 2mg bars) and I am usually take a 1mg(Alpraz) around 6pm and then 1.5mg at 8 or 9 pm...

MY QUESTION: I know 2mg is the biggest they make in Xanax other than 3mgXR but is it really considered a BIG dose??? I ask because Vicodin 10mg is the biggest they make but that is a very small dose... So can anyone tell me what would be considered a HEAVY(not deadly) dose of Alprazolam would be??

***This question sounded better in my head, I'm sorry if it runs together and doesn't make much sense....
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It depends on your tolerance.

While on buprenorphine, if you take benzos, the synergy is going to allow for a lower dose of benzos.

I would recommend only taking 1mg or 2mg (with a tolerance) of alprazolam, tops. If you're looking to take more than that, it's hard for us to say where the line should be drawn.

It really depends on your tolerance. I don't advise taking large doses of benzos; it only leads to brain damage, and a stupor at best.

Also, vicodin has nothing to do with benzos, it's not really a strong opiate even. The idea of what a "big dose" is won't be explained by comparing benzos to vicodin.
 
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I typed in:

potentiate suboxone
potentiate buprenophine
potentiate subutex

and only 1 result came up for the first one ; and in the post they told the poster to UTFSE. So what I am supposed to get out of that?

Isn't this supposed to be a harm reduction site? If I have a legitimate question to help me get off drugs, I get "UTFSE" and "post closed", but if you're some 14 year old who wants to know how to inject some random pill he found in parent's medicine cabinet, there is all sorts of tips and tricks and links. Doesn't make sense.

If you feel it has been asked and answered too much , and don't feel like responding, why not just not respond? Let someone that does want to, help.

Even if I did find something, which I didn't, it might just be someone who's snorting them or injecting them wanting to get higher, which is ok, I but it's also OK to want to quit and make the most out of a limited resource.
 
You can use the clonazepam with it if you want.

You don't give much info:age? drug experience? etc. If you know what you're doing with benzos and know your tolerance you should be able to safely combine the two. You should be aware that most OD's on bup are due to IV use in conjunction with benzos and/or alcohol .

Bup has a long half-life so you can play with that as well. If you want to taper off opiates 13mg is probably plenty. You just wait until you are starting to feel withdrawal (very important or you will be sorry) . Cut up your pills into peices that you will know the approx. dose ( I usually do 2mg peices) and on day 1 take as much as you need to feel OK . The first day is usually pretty rough d/t adjustment to partial agonist with less intrinsic activity. Take 2mg sublingually and wait about an hour or so if you can before you redose. I usually get somewhere in 2-4mg range (and I've been at this for a while now so high doses usualy aren't needed for this purpose IMO).
Take that dose for a day or 2 then start to taper with the remainder in decreasing doses once a day until you are taking crumbs at the end (if necessary). Of the top of my head I think the half-life is 24-36 hours but I may be off a little with that. The point is it's long.

Use the clonazeam as sparingly as possible throughout and you should experience minimal discomfort at least when compared to cold turkey. Doesn't mean you won't feel uncomfortable at times because you probably will.

Bup crash course.
 
Grapefruit juice. Using this juice alongside your subs will increase the halflife of your dose, somewhat. Don't expect it to do anything magical (like suddenly allowing you to get high off your dose), but do not be surprised if you notice you can go a few more hours without getting sick off the same sized dose as you normally take.

St. John's Wort. This does the opposite of grapefruit juice in regards to the liver. In the case of Buprenorphine though, this means that you will get a slightly higher level of bupe's metabolite, norbuperenorphine. Norbupe is a stronger agonist of the mu receptors compared to just regular bupe. (Basically, norbupe has a better chance at getting you ''high'' compared to regular bupe) Be aware though that bupe itself still has a higher binding affinity than norbupe, meaning you will still encounter somewhat of a blockade when it comes to norbupe actually being able to bind to its receptor sites.
 
If you dose normally (ie 1 or 2mg at a time, not 8 or 16mg at a time) then the norbuprenorphine will do an excellent job of activating the mu-agonist receptor. The idea is, there's a limited range that norbuprenorphine gets within your body - if you supply more of its source, it out-competes the mu-opioid receptor for it.
 
Excellent post Edarrin ... agree.

The other thing that people forget to mention is that subs / bup is measured in MICROgrams, and a 1mg can't be cut small enough to properly taper: that is you can get very good mileage from your 13 pills even if you try quarters when you feel the discomfort coming on.
You can always take more if no result, but give it a chance to work
 
Ya I asume they meant milligrams but, if not please explain.

I didn't read the whole thread so maybe this has been said but, has anyone mentioned the use of alcohol with suboxone sublingualy? If not sixpartseven made a great thread about it. The gist is by using alcohol like rum or vodka with the bupe the drug is better absorbed. Just disolving the suboxone in the liquor and absorbing it into a small piece of cotton let's you easily use it more effectively sublingualy.

If someone already said this(likely) sorry. Tl;dr
 
Capt H, I've done it mate 1x10mg diazepam follow by 3x0.216mg sub with whiskey about 10mins ago so now i'm just waiting to see what happens...will keep u updated and hey i wanna say once again thank you so much for your help and have a good one mate??

Cheers,
 
ahlongsan said:
Capt H, I've done it mate 1x10mg diazepam follow by 3x0.216mg sub with whiskey about 10mins ago so now i'm just waiting to see what happens...will keep u updated and hey i wanna say once again thank you so much for your help and have a good one mate??

Cheers,
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Nice. I'm definitely having a good one at the time being, be safe and enjoy the experience.
 
Johnny blue said:
Ya I asume they meant milligrams but, if not please explain.

I didn't read the whole thread so maybe this has been said but, has anyone mentioned the use of alcohol with suboxone sublingualy? If not sixpartseven made a great thread about it. The gist is by using alcohol like rum or vodka with the bupe the drug is better absorbed. Just disolving the suboxone in the liquor and absorbing it into a small piece of cotton let's you easily use it more effectively sublingualy.

If someone already said this(likely) sorry. Tl;dr
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Nobody said anything about it because there's plenty of info on this in the megathread, and in 6/7's thread: http://www.bluelight.ru/vb/showthread.php?t=404947

But that's OK, I like this method, so feel free to discuss it here.

Lost and Confused said:
Uh...hmm.

Why potentiate suboxone?
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If you don't have health insurance, it's a lot of money to pay to only get 30% out of the active ingredient.
 
Capt H,
I'm having it nice now , really talkative and genaral sense of well being and just......hmmm feeling really really good mate much better than my cwe 150mg of codiene ...cheers once again mate will keep u updated as the day goes on...
 
ahlongsan said:
Capt H,
I'm having it nice now , really talkative and genaral sense of well being and just......hmmm feeling really really good mate much better than my cwe 150mg of codiene ...cheers once again mate will keep u updated as the day goes on...
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Cool, sounds like a typical buprenorphine experience.

I typically dose the equivalent of 7 of those pills at once (about 1mg of buprenorphine), but used to be on heroin for quite some time. My opiate tolerance is much lower than it once was.

Glad to hear you enjoyed it.
 
Captain.Heroin said:
It depends on your tolerance.

While on buprenorphine, if you take benzos, the synergy is going to allow for a lower dose of benzos.

I would recommend only taking 1mg or 2mg (with a tolerance) of alprazolam, tops. If you're looking to take more than that, it's hard for us to say where the line should be drawn.

It really depends on your tolerance. I don't advise taking large doses of benzos; it only leads to brain damage, and a stupor at best.

Also, vicodin has nothing to do with benzos, it's not really a strong opiate even. The idea of what a "big dose" is won't be explained by comparing benzos to vicodin.
Click to expand...

I know Vicodin has nothing to do with benzos, that was the whole point of the question... anyways, thanks for the advise and It seems as thought I built a tolerance QUICKLY b/c when the first time I took a xanax was last week and I took .5mg and got messed up but now I can take 1mg and I feel good but not tired and nodded out... So I think I'll stick with that...

But thanks again Capt. cause had you not answered that question I'm the type that would have kept upping the dose.... I'll be sure not to take over 2mg...
 
capt H, latest update is great feeling of euphria and very talkative(is that normal??) till about 6 hours after the dose then i sort of just lie down and pass out for an hour. woke up and the euphoria's gone and all's normal again so pretty good expreince all in all. i think i did the sub part wrong coz i stick all 3 pills at once under my tongue with alcohol and the alcohol was horrible to hold in my mouth for too long so i sort of chew it all up to help it dissolves and then swallow it all.....so maybe i didn't get the most out of the 3 pills( what do u reckon??) any advise to maximise the 3 pills?? or do u reckon i've got it right already????

Thanks in advance again for your help mate.....

cheers,
 
quick Question for you guys....i took 4mg under the tounge( so really that would be 2mg in my system (correct?) roughly 24 hours ago...could i snort or shoot the dope i just bought? or should i wait another 12-24 hours?
also, i been snortin dope a lot lately and couldnt find anything yesterday, so i took the 4mg(2mg) under the tounge, so its my first time using the bupe in a long time.
im staring at this needle and i just wanna fuckin boot it already damnet....think 24 hours is long enough to get the bupe/narcan completely out of my system so i can enjoy this dope 100 percent?
 
legitballer, there are TONS of questions exactly the same as the one you just asked, you would have found the answer if you had just searched.

no, after 24 hours, you ARE NOT going to feel the heroin 100%. i believe you will feel it but it wont be that good. i would wait another day or 2. also, if all you wanna do is shoot up heroin, then why are you on suboxone in the first place?
 
Suboxone Withdrawals

So I UTFSE and didnt find much help. I've been on 4mg - 8mg Suboxone a day for about 5 months. On a scale of 1-10 with 1 being no wd's and 10 being the worst, what could I expect? And about what would the duration be? I've withdrawn from alcohol many time so I know wd's are horrible but I really have no experience with opiate withdrawals other than some minor discomfort in the past. Any response will be appreciated. Thanks.
 
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