Bupe Suboxone/Buprenorphine FAQ and Megathread v.1; 2007 - 2010

[Oxymorphone]

So how long should I be on 6mg until I taper down to 4mg?

And are you sure not tapering and just taking 4mg twice a day instead of 8mg once a day wouldn't make a difference? I still get more positive effects than negative from bupe.

You could go from 8 to 6 to 4 in two days, it's really easy. I went from 8-16 to 2-3 in a day and felt no difference. Now I take an equivalent of 1-2mg IV per day and feel great. I want to get to .5-1 it's jsut hard dosing it that small and keeping it accurate.

To get 1mg I have to approximate .3mg from an 8mg pill which isn't so easy. When I get my filters I'll make a solution with a ratio of .1mg per 10 units (20mg suboxone with 20ml of water) for easy and accurate dosing so I don't have to guess. when i do that my goal will be to get down to .1mg or .15mg IV daily, then I should be able to get high when I want and I am at a low maintenance dose that I could potentially come off of, but I have a feeling I will need a low dose for a while and I like the daily ritual.

 

[Free_Man**]

Some people would say the same thing to injecting street drugs, or injecting anything at all.

He's going to try it anyways, it's better to tell him the truth instead of "don't do it, dude".

fair enough - i dunno , i guess im just trying to make a difference
maybe help people wake up and see the truth about themselves

the truth is always good tho.....

 

[maggiegbl]

Subutex withdrawal - Citaprolam (Celexa) experiences?

HI,

Been using Subutex as a maintenence regime for nearly 4 years and been clean the entire time.

Recently decided to taper, which I did very slowly, but inadvertantly got addicted to valium during the process. (this is all in another thread so ill try and keep this breif as poss)

Anyway, long story short - after a hellish few weeks of sleep deprevation, extreme dis-phoria, I am back on small doses of Subutex.

I want to taper off again as soon as I have the valium out of my system but will need something to help with the dis-phoria, manic deppression, sleep.

The Dr has recomended Citaprolam (Celexa), Just wondered if anyone has had any experience with it's use for withdrawal. Or has any alternative ideas?

 

[ashla]

sorry maggie i am no doctor but i am almost one hundred percent celexa will not help with withdrawal, maybe you can ask him for clonidine and it sucks bout the benzo's cuz i went through that as well,
i will tell you though i kicked a huge methadone habit it prison and it sucked ass bad but eventually your body will go back to normal, excercize alot of water, healthy diet, sleeping well
also if you had a rough time before just go slower it isnt a race well unless you have personal reasons to come of sub, goodluck but gotta tell you celexa wont do shit for the withdrawal maybe would help after your done withdrawing with depression and shit like that ashla

 

[DeLee]

Got a question, if some of you are in the same situation or have been.

Im prescribed 20mg Citalopram and have been on it for over 3 weeks.
And just want to know if there is any significant interaction between Citalopram and Suboxone?

 

[Free_Man**]

^^ probably not man - citalopram is fairly safe i was on 60mgs a day at one point

i think it interferes with cyp2d6 - im not sure if this cytochrome is used with bupe ?

some one here will know....

 

[DeLee]

^^ probably not man - citalopram is fairly safe i was on 60mgs a day at one point

i think it interferes with cyp2d6 - im not sure if this cytochrome is used with bupe ?

some one here will know....

Yeah your probably right, the medicine's doesn't mention any dangerous combination between them but i still like some peoples input.

It might just be that i haven't used opiates in about 1month (suboxone that time too) but yesterday i got really high from just 0.5 mg Suboxone IV and right now
i just took 0.5 mg IV and got very high again.

Hard to focus sometimes, eyes going shut, very very small pupils, little wobbli walking etc.

 

[Oxymorphone]

Yeah your probably right, the medicine's doesn't mention any dangerous combination between them but i still like some peoples input.

It might just be that i haven't used opiates in about 1month (suboxone that time too) but yesterday i got really high from just 0.5 mg Suboxone IV and right now
i just took 0.5 mg IV and got very high again.

Hard to focus sometimes, eyes going shut, very very small pupils, little wobbli walking etc.

You lucky mofos getting high off IV suboxone, damn I want it to happen for me already. The only time I got high is when I got stuck for 4 days without it and was WDing then took an 8 under my tongue.

 

[Pegasus]

There is a great resource in the OD directory dealing with all the cytochrome CYP450 interactions... Here is the thread.

Edit- Looks like buprenorpine interacts with cimetidine at the 3A4 pathway.

 

[opiomoter]

suboxone dosage?

So i recently came of an oxy binge which lasted a month. I wasnt taking too much, maybe about 80mg a day, and I just recently quit. The withdrawal symptoms were pretty bad but they only lasted for 3-4 days surprisingly and now I feel fine. Anyways, my doc gave me a script for 8mg suboxone, but I never ended up using them because of the short duration of my withdrawals. Ive been clean for about a week now, and I still have those suboxones sitting around, would I get high by taking one? Someone told me that I should due a very small amount like maybe a 1/4 pill, so 2mg worth? Also, should I take it sublingually, or snort it? Anyways, im still relatively a rookie when it comes to opiates, so any advice or help would be great. Thanks.

 

[Oxymorphone]

1-2mg, 3mg at most if you want to get high, use the megathread, all answers are there on the first page.

 

[PillPoppingAnimal]

dont abuse suboxone...

i mean, experience it... but if ur really traking 80mg to get high than ur one of those people who have just a natural tolerance to opies.. so maybe u wont get high, but u could get the physical effects...

my friend blew 1/8 of a pill (no tolerence to opies), and was barfing ALLLL day

 

[Oxymorphone]

dont abuse suboxone...

i mean, experience it... but if ur really traking 80mg to get high than ur one of those people who have just a natural tolerance to opies.. so maybe u wont get high, but u could get the physical effects...

my friend blew 1/8 of a pill (no tolerence to opies), and was barfing ALLLL day

80mg is not natural tolerance, he will be fine, i always tell people to start with .5 or 1 at most.

 

[Jabberwocky]

So i recently came of an oxy binge which lasted a month. I wasnt taking too much, maybe about 80mg a day, and I just recently quit. The withdrawal symptoms were pretty bad but they only lasted for 3-4 days surprisingly and now I feel fine. Anyways, my doc gave me a script for 8mg suboxone, but I never ended up using them because of the short duration of my withdrawals. Ive been clean for about a week now, and I still have those suboxones sitting around, would I get high by taking one? Someone told me that I should due a very small amount like maybe a 1/4 pill, so 2mg worth? Also, should I take it sublingually, or snort it? Anyways, im still relatively a rookie when it comes to opiates, so any advice or help would be great. Thanks.

if youre going to try and get high from the bupe then i would personally start off with 0.5mg since youve just gotten clean - your tolerance will have dropped since coming off so starting small is the safe and smart thing to do.

snorting the bupe has a higher BA than sublingual and some users report a "rush" from this because its absorbed at a more rapid rate than sublingual use which in turn makes it more efficient dosing wise.

you can also increase the sublingual BA using the alcohol technique (link is available on the first page im pretty sure, in one of the first 2 posts or so)

hope this helped

 

[DeLee]

You lucky mofos getting high off IV suboxone, damn I want it to happen for me already. The only time I got high is when I got stuck for 4 days without it and was WDing then took an 8 under my tongue.

Hehe, yeah. Well I hadn't used any opioids for a little over a month.
I have used opioids on and off for the last 10 years.

But now when i started my SSRI Citalopram and started using Suboxone again I was amazed how high I got from 0.5mg Sub Intravenous.
It seems like the Citalopram is boosting the Bupe a bit, I don't know....

There is a great resource in the OD directory dealing with all the cytochrome CYP450 interactions... Here is the thread.

Edit- Looks like buprenorpine interacts with cimetidine at the 3A4 pathway.

Thank you for your post!
I must say I know nothing about these things.. but from a google it seems that Citalopram "interacts through?" cytochrome CYP450.
But does it affect Buprenorphine or Naloxone in any way? ( Like does cimetidine at the 3A4 pathway and the Citalopram have anything in common?)

I mean i most certainly don't wanna risk any Serotonine Syndrome here...

 

[Captain.Heroin]

So how long should I be on 6mg until I taper down to 4mg?

And are you sure not tapering and just taking 4mg twice a day instead of 8mg once a day wouldn't make a difference? I still get more positive effects than negative from bupe.

As long as you feel is necessary. If you do drop down to 6mg (either all at once or 4mg in the morning, 2mg at night) then your body will get used to this, and eventually you'll notice it holds you well. That's when you can drop down to 4mg (once a day or 2mg twice a day).

4mg twice a day might make a difference, but if you're going to do that then you might as well do 4mg then 2mg later - and see if 6mg holds you. You can always take another 2mg if necessary. I say this because it just makes sense that at night you would take less if you don't need it to last as long.

The idea is you ideally shouldn't get any negative effects from buprenorphine - negative effects are a sign you're taking too much (or the effective dose for you is higher than most people's). I don't get any negative symptoms from buprenorphine. That's just my 2 cents, maybe some people will always get negative effects from buprenorphine.

Got a question, if some of you are in the same situation or have been.

Im prescribed 20mg Citalopram and have been on it for over 3 weeks.
And just want to know if there is any significant interaction between Citalopram and Suboxone?

No idea, sorry. I don't have any personal experience with citalopram but I hear it gives people a lot of PR's though some people get good effects from it. I'm not 100% sure what will happen.

But does it affect Buprenorphine or Naloxone in any way? ( Like does cimetidine at the 3A4 pathway and the Citalopram have anything in common?)

I mean i most certainly don't wanna risk any Serotonine Syndrome here...

Buprenorphine doesn't effect serotonin (directly), and naloxone in Suboxone doesn't do anything, so there's no need to worry about it.

 

[Oxymorphone]

I just shot heroin for the first time in months. I know it's a relapse but damn it feels good. I want to get right back on suboxone so I don't start using regularly in full force again. How long should I wait after taking heroin before taking another dose of suboxone? Should I really wait until I am in withdrawal? There is still some suboxone in my system but I just shot half a bag (being vareful since i know my tolerance is down) and I'm flying. If there is still suboxone in my system will I get any precipitated withdrawal from one day of heroin use?


My god this feels like the first time I used all over again, whoever said you could never relive your first experience was wrong. :D

Now another hypothetical question, if god forbid I took too much or overdosed on another opiate, could suboxone help at all to force precipitated withdrawal and possibly save me or would it make it worse?

 

[Captain.Heroin]

Should I really wait until I am in withdrawal?

Yes.

There is still some suboxone in my system but I just shot half a bag (being vareful since i know my tolerance is down) and I'm flying. If there is still suboxone in my system will I get any precipitated withdrawal from one day of heroin use?

I'm not sure I've never experienced precipitated WD.

My god this feels like the first time I used all over again, whoever said you could never relive your first experience was wrong. :D

Most people say that IMO to deter people from relapsing.

Now another hypothetical question, if god forbid I took too much or overdosed on another opiate, could suboxone help at all to force precipitated withdrawal and possibly save me or would it make it worse?

In the event of an overdose you want to administer Naloxone via injection. You cannot do this with Suboxone, and taking Suboxone (any ROA) can make an overdose situation worse by adding respiratory depression.

If you are able to take a course and acquire naloxone, do that before using a lot of dope again. That, or call 911 when you OD (if you do - not everyone OD's).

 

[Foul Play]

I just shot heroin for the first time in months. I know it's a relapse but damn it feels good. I want to get right back on suboxone so I don't start using regularly in full force again. How long should I wait after taking heroin before taking another dose of suboxone? Should I really wait until I am in withdrawal? There is still some suboxone in my system but I just shot half a bag (being vareful since i know my tolerance is down) and I'm flying. If there is still suboxone in my system will I get any precipitated withdrawal from one day of heroin use?

In my honest opinion, you could probably jump back onto bupe without any interactions. I've done it a handfull of times over the last few years, without waiting untill i was in a good amount of w/d. Keep in mind tho, that everyone's chemistry is different. I've gone thru more than my share of precipitated withdrawal, but I've never gotten it from using 1 shot and getting back on track, only if i've been using for a few days or more.

I do suggest waiting at least 12 hours. In an ideal world you would wait untill you know you're ok to take it.. but I know the feeling of wanting to get back to normal.

And to using Sub's to counter an overdose, no it won't work. It won't work for the same reason why Sub's won't put you into pwd when injected.. it has a higher affinity compared to naloxone.

 

[tiimmmmmyyy]

Hello folks, new member here,

I'm an "ex heroin user," who was just prescribed 8mg suboxone 4 times a day (32 mg/day). Before being prescribed this, I was on 60 mg methadone/day for 2 months. I went through my wonderful weekend methadone withdrawal (by the way it took 36 hours for WD onset) and started my suboxone yesterday. I know doctors dont always care about their patients, so I'm worried about this high of a dose. This seems like it's going to be a bitch to get off of. I'd like to be opiate free, but once I get used to this 32mg/day regime tapering or withdrawal will take FOREVER and be terrible. Any advice at all? I start school at a difficult university in 2 weeks, so I can't be in 'long acting opiate' withdrawal during the quarter.

Also, so far it seems like I will not get high or nod like on methadone (or get bitchy and irritable), this is a correct assumption?

AND since stopping methadone I have been COLD as hell. No matter how many blankets I have on I am still cold. It couldn't be residual withdrawal due to my high suboxone dose (he had me take 40 mg today). Any insight into this?

Thanks guys, and I hope to become a part of this online community.