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Opioids stomach cramps which opiate is better? oral administration

C

chch

Greenlighter
Joined
Apr 20, 2013
Messages
37
I get terrible stomach cramps from codeine (Tylenol 3,T4). I've had some on morphine too. Not sure about oxycodone because I haven't taken much.

My question is, is there a better opiate such as the -codones for less or no stomach cramps? Or is it just a fact that they all cause bad cramps?

Do you get the same level of stomach pain from smoking -codones, morphine, etc as you would from oral ingestion?
 
I wouldn't advise smoking pills at all. I've never heard of stomach "cramps" per-say regarding opiate use, but nausea is a side effect of almost all opiates and it really only goes away with an increase in tolerance.
 
I think I mean pancreas pain from that sphincter of Oddi. I'm not sure but they give me a cramp around the stomach or pancreas area. maybe it's just some other problem, because I've had some cramps for years.
 
I don't think the stomach cramping would be from opiate use. I've never really heard of anyone complaining of cramping from opiates. I've also been an opiate addict for 11 years and never had stomach cramps, or any kind of cramp for that matter besides ones related to dehydration.

Maybe you just have a stomach problem? Crohns maybe?
 
Is this after you use the pills? That would be withdrawal. Dont smoke a pill. Thats dumb and bad for you. Maybe your body doesnt like opiates. I have never gotten stomach cramps except from alot of tylenol. Some people cannot stomach tylenol. Oxycodone comes without tylenol in some doses but than again so does morphine in all doses.
 
codeine and morphine can cause minor stomach irritation but generally not cramps as all opiates relax the digestive system.
Oxycodone is sometimes used when patients cant tolerate morphine and if its any good for you tramadol causes less GI upset as a general rule.
 
I've been using H for 8 yrs now and cramps are my biggest problem when hanging. I get all the others too, sweats, chills, aches, runny nose...but cramps really kill me. My mates don't get it near as bad. So I think everyone is different. I think its cos my bowels are generally very sensitive. I get the runs really easy (e.g. hanging/travelling), and always have bad constipation (from gear use/also, when travelling lol)...I have no suggestions. The only thing that cures my cramps is a shot of H or a swig of (m)done.

For the dude who says cramps aren't related to withdrawal, I can assure you that you're mistaken.
 
chch said:
I think I mean pancreas pain from that sphincter of Oddi. I'm not sure but they give me a cramp around the stomach or pancreas area. maybe it's just some other problem, because I've had some cramps for years.
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Yes opioids can cause spasms of the sphinter of Oddi. It's not super common, usually happens to people who have pre-existing problems with the sphincter of Oddi, the opioid just exacerbates it/brings on attacks. It's possible some opioids are worse for causing it than others but I don't really have a complete list, I'm not sure whether or not the Other Drugs mods would consider it harm reduction to post such a list or not because some of the opioids would be stronger. But yeah I think codeine and morphine are particularly bad for causing it. Not sure about oxycodone. Maybe you should just avoid opioids?
 
Is there perhaps any proven alleviation from post opiod stomach cramps. Granted I am withdrawing from lowly Kratom only and while the other issues are mild the lower gut cramps are a seriously painful nightmare. Stomach cramps like an ear ache are totally debilitating to the point of being ridiculous. Is this synonymous with real opiates?
 
blight12 said:
Is there perhaps any proven alleviation from post opiod stomach cramps. Granted I am withdrawing from lowly Kratom only and while the other issues are mild the lower gut cramps are a seriously painful nightmare. Stomach cramps like an ear ache are totally debilitating to the point of being ridiculous. Is this synonymous with real opiates?
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That is a different issue than the OP is talking about, you are talking about withdrawal cramps, in the abdominal area, correct? It's because opioids are constipating and then when the opioid wears off the reverse happens and your guts start spasming and trying to move the compacted waste in your intestine/colon. Loperamide (Immodium) can help, but note that it's an opioid too (although mostly acts peripherally) so you'd want to use it sparingly in as low a dose as possible and taper off it. Something that softens stools like magnesium is good unless you already have diarrhea. And make sure to drink tons of water. I find gentle massage and heat to help some. Also have you quit kratom completely or are you just asking how to help the cramps when you have to go a day without it? (because if you aren't quitting kratom I can give you some tips on how to help prevent the cramping to a degree)
 
^^ Yeah thats my problem. Spasms make sense, ill get something for that. Thanks.
 
Well i get stomach cramps due to what my gastroenterologist thinks is irritable bowel syndrome and maybe a food allergy as well (i am waiting to get more results back) and opiates don't kill all the pain. Also when i run out of opiates the cramps get way worse due to opiate withdrawal. I find that for both opiate withdrawal and non opiate withdrawal related stomach cramps Buscopan (hyoscine butylbromide aka scopolamine butylbromide aka Butylscopolamine) which is a form of scopolamine that does not cross the blood brain barrier is the best drug for stopping stomach cramps. I don't find loperimide to work that great for stomach cramps even opiate withdrawal related stomach cramps but everyone is different. All the same if the loperamide does not help you i would recommend trying buscopan as it can be gotten OTC in alot of countries and even if it's not OTC doctors have no reason not to prescribe it as it's not a scheduled substance of any type. I have not tried the other popular anti-spasmodic dicycloverine but it's a anti-muscarinic just like buscopan is except it crosses the blood brain barrier so it will give you the typical anti-cholinergic effects..
 
^Yeah I was actually going to mention Buscopan, the only reason I didn't is it's not available OTC where I live, I had it prescribed. I don't know if that's a Canada-wide thing or not but I have a vague recollection that you said it another thread that you couldn't get it OTC either. I forgot that other countries may have it OTC.
 
I've found that taking a shot or two of supplemental-grade aloe vera gel clears up all my stomach troubles from opiates, including loperamide.
 
it seems that morphine sulfate alone doesn't give me bad cramps, but an equipotent dose of codeine in Tylenol 4's does give me bad pain/cramps around stomach. Could it just be the acetaminophen? the doctors keep telling me its the opiates to discourage my use of them, but I'm not inclined to believe quacks without supporting evidence from google searches.

how is it that these quacks are too lazy to search the internet? they just have to spew out their med school crap over and over till it sounds like reason.
 
chch said:
it seems that morphine sulfate alone doesn't give me bad cramps, but an equipotent dose of codeine in Tylenol 4's does give me bad pain/cramps around stomach. Could it just be the acetaminophen? the doctors keep telling me its the opiates to discourage my use of them, but I'm not inclined to believe quacks without supporting evidence from google searches.

how is it that these quacks are too lazy to search the internet? they just have to spew out their med school crap over and over till it sounds like reason.
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Doctors simply don't have time to thoroughly research every drug. It's generally more of a problem with the way the health care system works than doctors themselves.

I think it's more likely to be the codeine than the acetaminophen. Have you ever taken acetominophen by itself and if so did it cause this symptom?

Opioids are known to cause spasms of the sphincter of Oddi. Codeine is one of the worst ones for doing so. Drugs like tramadol, pethidine, buprenorphine are less likely to cause attacks. Oxycodone and hydrocodone can cause it but I don't know how they compare to codeine in that regard.
 
Could it be the apap in your meds, if your taking tylenol 3 or something??

IF it's the tylenol then that rules out alot of options as far as codien and hydrocodone, although you could try vicuprofen or something similar. Try a CWE to determine whether it's the APAP.

If it's the opiate itself causing the nausea then i would reccomend either talking to doc about a different medication or seeking out a good antiemetic or certain benzodiazepines that will help with the discomfort.

Opioids never hurt my stomach unless too much apap is involved..i once vomited after about 9 vicodin and a few beers..bad choice lol don't drink on apap!
 
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