For me personally, I can't say that I've noticed much of a decrease in strength of the trip a full stomach, just takes a bit longer until onset and then peak. If I take a 4-substituted tryptamine on an empty stomach I'll probably get first alerts 15-20 minutes later. On a stomach with some food content onset is typically between 20-40 minutes. I'll typically eat a light meal 1-2 hours before taking my dose, sometimes I do eat a meal then immediately drop. Then during the trip I be sure to have fresh fruit to snack on and some ice cream. On an empty stomach the peak hits me much quicker which makes it feel more intense initially, but the strength of the trip itself isn't significantly affected, just the sensation of intensity.