Stimulants of the Future

[Reminisant B]

Similar compound to that I remember seeing on pubchem...

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=637720

wasn't sure whether it would be any good as stim though.

(R)-5-phenyloxazolidine definitely looks like it should be.

Does anyone know what happens if you start adding groups on the benzyl parts of desoxypipradol?

 

[jah]

Does anyone know if desoxypipradrol and pipradrol would breakdown to the same metabolites?8)

Thanks.

 

[Refluxer]

I'm guessing yes, but in different ratios from eachother. I'm very new to the metabolic pathways, and I'm not sure because of the disubstitution on the benzylic position. Perhaps desoxypipradrol is aromatically oxidized to a larger extent than pipradrol.

 

[hussness]

Here's another chemical along the lines of my last post which I'm not sure has been probed. It's slightly more along the lines of a cyclic cathinone derivative.

 

[fastandbulbous]

^ The analagous pyran is an active stimulant and moderate appetite supressant, but that's all I can remember off the top of my head (the pyran was one of a bucketload fed to rats)

 

[dbailey11]

Alright, I got the tibby tip on the ultimate stimulant of the future. Ready...

GODSPEED

HAHAHA, Sorry, fuck me man I couldn't help myself

 

[johanneschimpo]

Funny

 

[fasteddie]

I disagree with MDPVagrant - MDPV is really in the reacreational meth substitute camp. Too compusive to use in low doses long term. Eventually it leads to higher, compulsive dosing in most if not all that take it. Sortof like using coke to get through the day. Works for a while, but eventually will get out of hand.

To me, the real bad downside of MA is the incredibly prolonged duration of action. There's no ester bond to hydrolyze or OH group to glycosylate. Does this compound you allude to have that quality?

When, once upon a time, I might have ingested MA, I'd get so sick of it. Though, I was never a daily user, even at my worst.

Pardon me if this info has been discussed already. This is a very long thread.

 

[nuke]

The duration for MDPV is about 2-4 hours. MA usually last 7-10 or so (at least, for me).

 

[fasteddie]

The duration for MDPV is about 2-4 hours. MA usually last 7-10 or so (at least, for me).

Ahh, thanks.

The search for a happy medium...MA is too long. Cocaine is too short, as well as being hideously expensive, and the fact that one is thereby subsidizing some of the worst dirtbags on gods green earth.

 

[haribo1]

The search for a happy medium...MA is too long. Cocaine is too short, as well as being hideously expensive, and the fact that one is thereby subsidizing some of the worst dirtbags on gods green earth.

Very good point. MDPV is nice, but I would guess it has the potential to be very addictive. Wonder if anyone has tried MDPV with cocaine?

 

[hussness]

Wouldn't the much higher affinity of MDPV for DAT and NET block most of the effects of the cocaine?

 

[MDPVagrant]

Deleted

 

[dbailey11]

I'm going to apologize right now for my question- but I'm interested. If cocaine is a dopamine agonist, and l-dopa is a dopamine precurser, why are they nothing alike in terms of effect?

 

[hussness]

^The link I've pasted below should shed some light on that.

http://www.bluelight.ru/vb/showthread.php?t=301915

 

[fasteddie]

Ahhh, now I get it. methylene dioxy pyro valerone. I'm a bit slow on the uptake, today.

How about plain pyrovalerone? I see that's been scheduled a number of places, but I find little information about it otherwise. I found out about it lurking here.

 

[dbailey11]

Good lord that's alot of text to plod through. Anyone with a slightly condensed version care to answer? Thanks none the less hussness.

 

[haribo1]

It might block some of cocaine's dopaminergic effects, but IMO MDPV is actually a good deal better than cocaine in this dept. so it would hardly matter.

That's why I thought it might be good with cocaine or some related compound...

 

[Reminisant B]

Of course, it lacks cocaine's vasoconstricting and (some of) its cardiotoxic effects, so it's a tradeoff I guess... I'd take MDPV over coke any day as far as sex boosters/aphrodisiacs go, but coke definitely wins the day in a social/party atmosphere.

Possibly in terms of harm minimisation its not ideal to make statements suggestive off MDPV being less toxic than cocaine.

Even drugs that have passed phase III clinical trials can be withdrawn. 8( Can sometimes be better the devil you know - cocaine is far from ideal (toxicity) but A LOT is known about it.

 

[MDPVagrant]

Possibly in terms of harm minimisation its not ideal to make statements suggestive off MDPV being less toxic than cocaine.

Good point... consider this a retraction of any such statement I may have made (deleted earlier posts anyway).