Not sure about Adderall however I know from personal experience it never made any noticable difference in high dose meth usage. I started meth months before stopping SSRI's. It was awesome. I stopped SSRI's and have not noticed a change, or any better effect. In fact i noticed a more pronounced hangover and comedown and some extended depression the 2-3 days after. Prob due to the Serotonin effects now becoming active and contributing to the negatives. Meth without its supposed Serotonin effects seems to me just as awesome as without. I doubt the SRI action has any noticable effect on the high in reality.