D dxdy Greenlighter Joined Nov 11, 2014 Messages 2 Nov 11, 2014 #1 How stable is cocaine HCL in a solution of anhydrous methanol or anhydrous isopropanol? I know that in aqueous solution there will be hydrolysis of the ester groups, but what sort of degradation occurs in dry alcohol?
How stable is cocaine HCL in a solution of anhydrous methanol or anhydrous isopropanol? I know that in aqueous solution there will be hydrolysis of the ester groups, but what sort of degradation occurs in dry alcohol?
sekio Bluelight Crew Joined Sep 14, 2009 Messages 21,989 Location streets of simcity Nov 11, 2014 #2 I'd expect there would be transesterification with anhydrous methanol.
D dxdy Greenlighter Joined Nov 11, 2014 Messages 2 Nov 11, 2014 #3 I thought that would happen instead of hydrolysis only if ingested. Would using anhydrous isoproponol help avoid this issue?
I thought that would happen instead of hydrolysis only if ingested. Would using anhydrous isoproponol help avoid this issue?
