SSRI's and 6-apb harmful combo?

[Sleepwalker18]

My 6-apb should be here in a couple days, wondering if my 40mg's Paxil will interfere in any way, or if I have the risk of Serotonin Syndrome. Thanks :3

 

[pally pete]

My 6-apb should be here in a couple days, wondering if my 40mg's Paxil will interfere in any way, or if I have the risk of Serotonin Syndrome. Thanks :3

Id say eer on the side of caution as they both effect serotonin afaik.

 

[daytryptr]

Yes. Bad idea. Mixing a serotonin releaser (6-apb) with something that inhibits its re-uptake (ssri) can very easily lead to serotonin syndrome. If your not convinced do some googling into how the two drugs work, and why taking them together could lead to a fatally high level of serotonin should become obvious.

Be safe.

 

[Sleepwalker18]

I understand that they do indeed do cause damage. Little depressing :cc

 

[spephspeph]

This is indeed a bad combination, as I found out last summer.

40mg Fluoxetine daily (at the time) + 200mg (approx) 6-apb turn what should have been an enjoyable night at fabric into something of a nightmare.

The next day I was a miserable ratbag.

 

[Allein]

I would also (and have done) avoided such combinations for the reasons already stated.

I am interested to understand the mechanism a little more though as taking MDMA on and SSRI seems relatively common but on the basis of my basic understanding of Serotonin Syndrome would carry the same risks ?