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Opioids SR-17018 Is the future of opioid detox medication. Painless easy cheat to avoid withdrawal that is too good to be true, but it is legit and real.

Quasimoto said:
For reference, this is similar to kratom alkaloids. They are heavily g-protein biased and do not effect b-arrestin. This is why they do not cause respiratory depression, and are less euphoric than other opioids.
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I'm reading about SR-17018 on this forum and I have already committed to getting some in an effort to reset my opioid, 7OH, and pseudoindoxyl tolerance and step down-to-off kratom alkaloids and my Rx opioids.
I'm wondering if the similarity of affected receptors @Quasimoto mentioned in the quoted text means the SR-17018 will be more or less effective in reduction of WD from the kratom alkaloids?
Alternately I could drop the kratom completely switching to Rx meds, and then SR-17018.
Any help is appreciated!
 
Biomed Tech Guy said:
I'm reading about SR-17018 on this forum and I have already committed to getting some in an effort to reset my opioid, 7OH, and pseudoindoxyl tolerance and step down-to-off kratom alkaloids and my Rx opioids.
I'm wondering if the similarity of affected receptors @Quasimoto mentioned in the quoted text means the SR-17018 will be more or less effective in reduction of WD from the kratom alkaloids?
Alternately I could drop the kratom completely switching to Rx meds, and then SR-17018.
Any help is appreciated!
Click to expand...
A friend & me both were able to stop 20-30g per day kratom intake with three times 20-40mg SR a day.
Zero withdrawal symptoms
 
CavernsoftheMind said:
A friend & me both were able to stop 20-30g per day kratom intake with three times 20-40mg SR a day.
Zero withdrawal symptoms
Click to expand...
Thanks.
I've been in pain management about 13 years.
1 year ago discovered I could do a total swap from Rx meds (oxy IR and MS ER) when I "ran out early" to kratom alkaloid tablets. Started with about 6-8 15mg tabs per 24-36 hours.
About 2-3 weeks ago I recognized my kratom alkaloid intake had reached a dangerous point. Mainly from not being able to sleep more than 2-3 hours without having to redose to avoid pain and sweats. I didn't have any Rx meds at the time.
I'd gone beyond 1,000mg of 7OH and 70mg of pseudoindoxyl every 24 hours. Reading posts from forum members having problems and concerns about their use going over 400mg per day caught my attention too.
So I got my monthly Rx of MS ER and oxy IR refilled 10 days ago and hit them pretty hard, stepping down off the alkaloids as much as possible.
Hoping to use SR-17018 to get a rapid taper & reset on both.
 
4DQSAR

Post in thread 'Sr 17018 / RC opioid detoxes'

BTW I'm uncertain if any patent specifically cites Sr 17018 as a novel tool for detoxification.

Because you cannot patent something that is already public knowledge.

So people asking if Sr 17018 will ever be used, unless that patent exists, it's never going to make it to tke market. It's non potent enough to replace oxycodone anyway, so detoxification is the only path left... IF it's now left open.

I strongly suggest that the discoverers would not have made it public UNTIL it became apparent that it could not be taken to market.

I wouldn't put it past dubious but costly detox...

I knew I had done some research in the past.

The thing is, I couldn't find any human trials that were designed to test the inherent safety of SR-17018. While one may reasonably consider a 'trip report' as an unstructured case study (and therefore evidince - although low quality evidence in the scheme of things), I suggest that reports will inherently be subject to 'survivorship bias' i.e. if things go VERY badly wrong, the BLer who suffered the 'negative outcome' is no longer in a position to warn others.

By all means self-experiment with a novel chemical. It's your body so it's your choice. But you cannot extrapolate inherent safety from a small number of case reports.

I do keep asking but is SR-17018 an effective analgesic?
 
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Thinking about picking some SR-17018 up just for a "what if" scenario. I am currently on Suboxone. Either tomorrow or one month from now I'm going to do to Sublocade shot. Probably tomorrow if the doctor gives the go ahead. I am a chronic Kratom relapser and it'd be nice to have something around to help just in case I do fall back into addiction, before they ban this drug. I'm worried that it may enable me to justify taking kratom again, but I think if I'm looking for reasons to use it I probably will regardless if I have that safety net or not
 
SuperPsych said:
Thinking about picking some SR-17018 up just for a "what if" scenario.
Click to expand...
I don't want to go into the reasons why right now but I have my reasons for concern that our "normal" wash/rinse/repeat cycle that's been going on and on may not, and if it doesn't continue the last thing I'd wish on anyone, myself included, is a CTWD on top of the apocalypse.
If SR-17018 is even close to as helpful as the best results reported, consider it a vital part of every SHTF kit.
(SARC) I don't think it's available in one of those "Emergency Personal/Family Prescription Meds" kits that have hydroxychloroquine, ivermectin, Z-Pack antibiotics and a steroid based respiratory treatment package as some of the most popular combos, but for what should be obvious reasons to those who find that Rx Kit to be part of truly being prepared and don't want to be debilitated by a Lore-Worthy Legend of the Worst WD Tale of Woe when "civil society" is being incinerated all around them, It should be..
 
I have a question about this SR-17018 if anyone can answer. Is the binding affinity of SR-17018 strong enough that it would cause precipitated withdrawals if taken too soon after a dose of a full-agonist opioid? Also, is SR-17018 capable of producing withdrawal in and of itself? If it is able to ease the symptoms of withdrawal as well as people claim then I assume that it can. I just don't understand how this drug works compared to say, suboxone.
 
SR-17018 is a non-competitive agonist so it does not cause precipitated withdrawal. Doesn't seem to have its own withdrawals either, or they are incredibly mild.
 
My wife and I are planning on getting some of this to come off suboxone. I’ve done a lot of research on this and from the all of the reports I’ve read, it has a 90 percent success rate. We are going to be filming our progress as well as writing everything up on here. Hopefully this is the miracle everyone says it is. I was reluctant at first but after reading the comments I am beyond excited to try this. Stay tuned!!!
 
XmrXdisasterX said:
My wife and I are planning on getting some of this to come off suboxone. I’ve done a lot of research on this and from the all of the reports I’ve read, it has a 90 percent success rate. We are going to be filming our progress as well as writing everything up on here. Hopefully this is the miracle everyone says it is. I was reluctant at first but after reading the comments I am beyond excited to try this. Stay tuned!!!
Click to expand...

Well I hope it works out for you.

I do not know where you got that figure from but it's rarely stopping use of opioids.... it's condinuing not to use them and I don't know of any data where ANY sort of cohort study was used and certainly no double-blind study. I don't say studies don't exist, but I did look for a long time and couldn't find them.

I did post all the links I could find as it was initially seen as a possible alternative to oxycodone. Exactly why it failed in human studies, I don't know.

All I will point out that the discoverers of buprenorphine only ever considered it's utility in ameliorating the AWS of opioids i.e. they foresaw it being used for a week or two, but no longer.

When I mention to people that in primate models it DID produce tolerance - it kind of suggests that my posted papers weren't actually being read. But importantly, that tolerance took much longer so yeah, there may well be a window of a couple of weeks. But beware of anyone shilling ANY medication.
 
It’s just out of the reports I’ve read. Only 2 out of 50 said it didn’t work perfectly for them. I’m sure there are more people who it doesn’t work for but I am just averaging the small amount of research that’s available.
 
Also, I am well versed in RCs, I have zero worries about getting a shitty product. I go straight to the source. But yeah, don’t buy anything off these idiots trying to make profit off this. Scumbags. If it works for me I am going to buy a bulk amount to help all my friends in the area get clean too. This drug needs to be shared with the world if it does what people are claiming.
 
XmrXdisasterX said:
Also, I am well versed in RCs, I have zero worries about getting a shitty product. I go straight to the source. But yeah, don’t buy anything off these idiots trying to make profit off this. Scumbags. If it works for me I am going to buy a bulk amount to help all my friends in the area get clean too. This drug needs to be shared with the world if it does what people are claiming.
Click to expand...

I hope you took in the KEY point - it may well be of great utility in helping people to stop using opioids but it's almost certainly only of utility if used for a couple of weeks. Like I said with buprenorphine - THAT was what the 1970s studies showed. Of short-term utility. But when the patent ended - people are now being parked on buprenorphine just like they used to be parked on methadone.

But do post and do let us know how it goes and indeed if it works a second time. Because as statesd, getting people drug free is only the beginning of the struggle. I'm still keen to know where that 90% figure comes from - so I can read it!
 
Oh I definitely understand what you mean, there’s always going to be some discomfort but the lack of PWD for users trying to stop using things like fentylogues or zenes is huge. I think I’m more than ready to stop opiates altogether. and have been looking for sublocade until recently when I lost my insurance. Sublocade is the best option at the moment for coming off but I really think this has potential to be the future of MAT meds. Idk I’m going for it… I fear, I won’t pull the trigger in time, the government will make it illegal, and once it’s 5k a gram they will have all these studies showing that I should have followed my gut. Gonna jump on this now. The positive outweighs the negative by a lot.
 
@XmrXdisasterX - You know, nobody is making this compound to help others out. There WILL be a business model behind it. If it IS as stated and it really does allow a mild AWS if used for a couple of weeks, that's not a hugely profitsble model.

I just understand how ALL pharmacuticals work. Mostly as time goes on, it becomes a worse deal for the consumer.

What I FEAR is that people get large habits assuming that each time they can obtain this stuff. That's why I pointed out that we don't know if it works as well the second, third, fourth... times. It would be lovely if it did - but I'm sure that price will spike.

It's so easy to say to yourself 'never again' but a year later you forget how bad it was.

Good luck and let us all know!
 
SR-17018 is legitimate. I have personal friends that have used it to great success.

But the last thread about it here was bait for scammers to utilize. Myself and others who replied were targeted with PMs, offering a source. Thankfully I didn’t fall for it (SR 17018 wouldn’t touch my tolerance from nitazene use lol), but others DID fall for it.

Be extremely wary.
 
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