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Opioids SR-17018 experiences, doses, tips?

Mushoku_Sensei

Bluelighter
Joined
Apr 29, 2024
Messages
1,094
Location
Germany
Okay I read a few posts on this topic but ( forgive me if I overlooked anything) I didn't find too much practical advice - aside being careful of OD after successful switch to the SR-17018. Ik it's always difficult because ofc everyone is different as well as the starting point of the intended taper. Ik there's reddit articles but I don't like Reddit and I'm hoping there are people here knowing about it as well 😜

I'll start with my own experience so far: starting point is/was a very irregular but pm daily use of various opioids. I tapered before from Tapentadol, Tramadol and very short episodes of heroin use (no high doses either). My main issue is that I have always relapsed and usually after less than three days 🙄...
So "effective suppression of cravings" really got me and I - probably - managed to get some. Can't be sure since I can't test it and didn't send it anywhere to make sure either. Anyways. Tested 4 mg and had no adverse effects. At ~20 mg 3x a day there was no physical WD. I was just as fine as I would probably have been with 300 mg Tramadol/day as Tramadol works very well for me and when I first started, 100 mg would give me a high for the whole day. So I'm that type.. ATM I would need more like 700-800 mg/day to get that effect, which I obviously don't want to risk (and which is why I'm mixing so much instead). Just saying that to give you an idea of where I'm at when asking about doses.
So 60 mg SR-17018/day was enough - for one day. Then I tried to get high again and just added the SR to the mixery... Which ofc didn't make sense as a strategy. (But there was no subtractive effect either). The point is: while I had no physical WD the cravings were very much present still. Today 20 mg in the morning lasted until 5-6 pm when I noticed first signs of beginning WD, getting tired and cold, joints feeling uneasy, irritation, all light but very clear. It took me until 7:30 before I could redose. 20 mg no effect, back pain started and my digestion too, two hours later 20 mg more didn't make much difference. At 60 mg (redosed sublingually after one hour) I felt hot, my face was flushed, but it took a while for all symptoms to cease.
I know that it's always bad to even let the WD start because I need much more to come out than I would to stay out of it in the first place, but today I just couldn't avoid it.

Now I'm starting to wonder about the peculiarities of this substance. So far I know the flushing mainly from Ket and smoking or shooting H, but there's really no opioid feeling or even much of analgesia. Also having a slight headache 🙄.

So: experiences, tips, dose advice?
 
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Update:
After being "stable" on SR-17018 for 3 days I tried to reduce my doses from 3x 20 to 3x 13 mg (as I was already in the lower dose range I thought I could ). It worked during the day but then I woke up at 4:45 a.m. (sweating and diarrhea) and couldn't sleep anymore despite redosing. 😑

So I increased to 4x 20 mg yesterday. Cravings appeared 5 hours after every dose.

Today shortly after a very early morning dose following a very late night dose was the first time I ever experienced having a happy/relieved tummy without anything special happening as an isolated and clear chemical effect. No brain buzz at all.

Today I notice craving the next dose 4 hours after every dose - Feels like I'm getting/ being addicted to that now and increasing my tolerance 💀

So far the best info on SR-17018 I could find:
(And the credit goes to... Reddit... )



So far I can confirm that:
+ maintainance dose should be taken for no less than 4 days
+ The difference between doses from 10 - 25 mg is much bigger than from 25 - 50 mg ( than from 50-100 mg with a ceiling effect around 100 mg which I didn't test myself though).
+ It takes hours to fully kick in. (Only redose after 2 hours minimum during calibration phase)
+a proper calibration phase is (would have been) needed

I would also add:
+ Maintenance phase means to stick to a schedule once it's set ( while adjustment might be necessary, it still means you're NOT in the maintenance phase yet and for me it feels 100% possible and likely to just slip into the next addition cycle when allowing oneself to increase doses as per the "cravings" )
+ Just because you're addicted to relatively low doses doesn't mean you can get away with a three day SR quicky 😒

Bad luck for me that I'm still nothing like truly stable while already close to running out... And the delivery took more than a month FFS...
 
So despite no visible interest I'll still write my conclusion:

I ran out that very night, waking up at 4:45 AM sweating and w diarrhea and took what was the last remaining ~ 5 mg. The "abdominal high" returned btw, likely due to what I took before also kicking in finally 🤷.
Let's say the symptoms of wd were minimal, although my temperature regulation is still a mess and I feel my bones slightly - guess it's self inflicted, but.. I had to test my tolerance right? And it's definitely not back to pre-abuse levels... 🫤.
Anyways. That stuff is still worth getting if you can and wish to quit or reduce opioids imo.
Even better would ofc be a truly scientific evaluation... But I doubt we're going to see that anytime soon... 🙄
 
If it helped you to kick opioids, that's awesome. But didn't you mention on another thread that if you underdose sr-17018, it leaves you with withdrawals that a dose increase won't help with? Or does the dose increase help, but only after the 2 hour absorption time has passed?

Also I would be real wary of side effects. This drug has not been extensively tested and no human studies exist. And drugs always have some downside, it just may be too soon to tell what the side effects are with this one.
 
If it helped you to kick opioids, that's awesome. But didn't you mention on another thread that if you underdose sr-17018, it leaves you with withdrawals that a dose increase won't help with? Or does the dose increase help, but only after the 2 hour absorption time has passed?
I remember what you mean. That was about the cravings. I still had them despite no physical symptoms of WD on a low dose of SR-17018. That's also why I increased dose and frequency just to realize you can spiral with that just like any other addictive substance... If I hadn't run out without chances of getting more anytime soon I might be through a few grams by now 🙄...
Discipline is still essential, so you don't just end up flipping addictions... Even though this one is clearly easier to quit.
Also I would be real wary of side effects. This drug has not been extensively tested and no human studies exist. And drugs always have some downside, it just may be too soon to tell what the side effects are with this one.
True words I know... I just really had to stop and was scared for good reasons to switch back to Tramadol completely for tapering... Don't need the double WD again I swear... And it's frankly speaking also too tempting for me to increase any conventional opioid in between and mess up all the efforts again and again as I did before so many times...
 
I remember what you mean. That was about the cravings. I still had them despite no physical symptoms of WD on a low dose of SR-17018. That's also why I increased dose and frequency just to realize you can spiral with that just like any other addictive substance... If I hadn't run out without chances of getting more anytime soon I might be through a few grams by now 🙄...
Discipline is still essential, so you don't just end up flipping addictions... Even though this one is clearly easier to quit.

True words I know... I just really had to stop and was scared for good reasons to switch back to Tramadol completely for tapering... Don't need the double WD again I swear... And it's frankly speaking also too tempting for me to increase any conventional opioid in between and mess up all the efforts again and again as I did before so many times...
Well, at least in your case sr-17018 seemed like a much better option for kicking than tramadol (which presents unique problems during withdrawals due to its SSRI effects) so I am happy it helped! But I know what you mean about discipline being difficult when trying to kick conventional opioids. If you have a gram of dope, the temptation to do it all in a day instead of parceling it out over a week is too powerful to overcome for most junkies. So maybe sr-17018 is easier to kick in the respect that you don't get euphoria from it?
 
Well, at least in your case sr-17018 seemed like a much better option for kicking than tramadol (which presents unique problems during withdrawals due to its SSRI effects) so I am happy it helped! But I know what you mean about discipline being difficult when trying to kick conventional opioids. If you have a gram of dope, the temptation to do it all in a day instead of parceling it out over a week is too powerful to overcome for most junkies. So maybe sr-17018 is easier to kick in the respect that you don't get euphoria from it?
💯 That's it yep. Although even the relief it brings is a challenge... For a junky like me lol 😂
 
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