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Heroin Speed ball getting deactivated by blood?

The transfer to 6-MAM will not occur significantly in the 1 min or whatever it’s in solution with blood. This is a shitty drugs / tolerance / psychosomatic issue
 
Blood will break down both the cocaine and the heroin due to the presence of nonspecific esteraaes.

A classic teaching biochemistry lab experiment is measuring enzyme activitivity in blood (spit nowadays because people are afraid of blood). If the enzyme still is active it is able to cleave a synthetic molecule that gains color, and you measure the color change to get an idea of the enzyme activity.

But, the enzymatic activity of a small amount of blood in a syringe will never degrade the drugs at a higher rate than the when the drugs are in the body.

The time taken to shoot wouldn't give the blood a huge amount of time to react with the drugs.
 
Skorpio said:
Blood will break down both the cocaine and the heroin due to the presence of nonspecific esteraaes.

A classic teaching biochemistry lab experiment is measuring enzyme activitivity in blood (spit nowadays because people are afraid of blood). If the enzyme still is active it is able to cleave a synthetic molecule that gains color, and you measure the color change to get an idea of the enzyme activity.

But, the enzymatic activity of a small amount of blood in a syringe will never degrade the drugs at a higher rate than the when the drugs are in the body.

The time taken to shoot wouldn't give the blood a huge amount of time to react with the drugs.
Click to expand...
Would 5 minutes make a difference?
 
I think it's just that when u hit the vein and register a little of the drug gets In your bloodstream, so by the time your able to shoot the full shot your body has already felt the initial lil rush from the first tiny bit and so u don't feel a rush from the rest
 
Rebornagain88 said:
I think it's just that when u hit the vein and register a little of the drug gets In your bloodstream, so by the time your able to shoot the full shot your body has already felt the initial lil rush from the first tiny bit and so u don't feel a rush from the rest
Click to expand...
im liking this explanation better. insta tolerance.
 
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