Interesting thread, old or not, since i got this exact type type of weird effect multiple times consistently, but more so like my whole mouth and throat and a bit further down was painful, felt very strange and didnt function the way it should, like it was receiving corrupted signals from the brain.
It felt like it was difficult to get food down like it wasn't working or something was stuck in there. Same effect with other actions like clearing the throat.
I couldnt find more info on this anywhere, even with posts here in OD and a trip report on exactly this. I was snorting only but somehow i can tell it wasnt the substance itself causing the effect through direct contact. It only occurred 1-2 days into a binge as well.
Its like you are sick but its nothing like any type of illness has caused before. Its a sore thoat without being a sore throat that feels anything like a sore throat you have ever had before. Only way to explain it.