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  • BDD Moderators: Keif’ Richards

Some Opiate Questions

Alright guys thanks again for the awesome information. Very helpful. I'll heed your warnings and stop experimenting once I run out (isn't that what everyone says? haha)

Anyways - just one question and I'll be out of your hair

1. I noticed when laying on my back and trying to fall asleep, every 5 or 10 seconds I would experience like a quick short exhalation. It's almost like a quick snore; however, there is no build up to it and it happens very randomly. I think I might be nodding out and this short burst is waking me back up. It's actually kind of scary. Has anyone else experienced something similar to this?

Best Regards

It almost sounds like you're describing sleep apnea. You may want to get that checked out because it "can" be fatal under the right circumstances; clearly nothing to mess with.
 
Buddy what you said at #3....about taking 10mg then an hour later taking another dose, donttt do that thats the reason your not really getting high.
Take a whole 20-25 mg at once to feel the acctual euphoria and high.

Usually with opiates you have to become accustomed to that feeeling before you can start enjoying it.
I agree that a person taking an hour between dosing will not feel eurphoria and you need to take it all at once
 
^Yeah, very true, but that's where it gets dangerous, you wanna do the whole thing at once to feel it, but you may not know your limit....particularly with H...you can guage it a little better with pharms
 
I'm willing to bet its the diphenhydramine that's causing your problems. Not all people enjoy all antihistamines with their opioids. Diphenhydramine is a known anticholinergic, and it can cause dysphoria and irritability. Try taking your oxycodone alone and you'll certainly notice a difference.
 
I've pretty much concluded my experiments with opiates...

Doesn't seem to be for me. I'll stick to know what I know and love (benzos)
 
Glad to hear you've found out what you're looking for.

If you decide you want to try anything else, you know where to go to find out information. :)
 
Some people already went into a fair bit of detail with regard to metabolism.

1. I have yet to experience any kind of euphoria. I have tried doses between 10mg and 30mg and the only effects I am noticing is drowsiness, impaired motor coordination, etc... none of the amazing orgasmic rush I hear other people experiencing. Could anyone shed some light as to why this is happening? Some quick research shows me that a small percentage of the population suffers from a CYP2D6 enzyme deficiency which prevents them from effectively metabolizing opiates. Is there any way to bypass this?

Additionally, I am very prone to nausea so I have been taking diphenhydramine with each dose (about 50mg-100mg); I have also read that diphenhydramine actually inhibits the same CYP2D6 enzyme which is not a good thing for a person like me who is chasing the euphoria. Does anyone know if there is truth to this or is able to expand upon it a little more?

Have you had experience with other opioids, and have you found them euphoric? A number of people simply don't get euphoria from opioids in general, and instead of 'pleasantly nodding off' find it a kind of uncomfortable stupor with nausea and drowsiness.

I personally don't get euphoria from doses below 30mg, and I don't get a massively euphoric rush from oxycodone at all - even if administered IV - but if you're already significantly nauseated, then I doubt it is a case of needing a higher dose for euphoria.

Euphoria is by no means a universal effect from opioids.
 
Opioids are kind of an acquired taste for a lot of people, I'd say....not worth aqcuiring the taste really!
 
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