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So Who Likes Benzos? Ver III: Blackouts and Amnesia

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Damn that 50mg temaz and half a bottle of scotch last night had me fairly messed up. Had to delete that nutty message. Was too much of a pussy to read it too.

So why is phenaz so potent, or is just that it often comes in powder form and people tend to eyeball it rather than weigh it?
 
It's roughly about the same potency as other potent benzodiazepines like lorazepam or alprazolam or etizolam. It is mainly an issue with the very long half-life and yes, people eye balling it.
 
If anyone is interested (and has access to a Uni library) here is an article on potentiating diazepam with GFJ.

http://0-www.springerlink.com.library.ecu.edu.au/content/6845136576857241/

Interesting that they administered the GFJ and the valium simultaneously. I wonder if the effects would have been and different if the GFJ was consumed 30-45min prior (as most sources online seem to indicate as the way to go).

Here's the abstract:
Grapefruit juice has been reported to markedly improve the bioavailability of triazolam, midazolam, terfenadine, cyclosporine and several dihydropyridine calcium channel blockers including felodipine, nifedipine, nitrendipine and nisoldipine. Because these drugs are metabolized by the hepatic cytochrome P450 isozyme (CYP) 3A4, the inhibitory effect of grapefruit juice is thought to results from inhibition of CYP3A4. In this study, our aim was to investigate the effects of grapefruit juice on plasma concentrations of diazepam. Eight healthy male and female subjects participated in this study. Oral (5 mg) diazepam was administered with either 250 ml water and grapefruit juice. Blood samples were collected for a 24 h period, and whole blood concentrations of diazepam were measured enzyme immunoassay. The mean AUC(0−24) of diazepam was increased 3.2-fold (P<0.001) and Cmax was increased 1.5-fold (P<0.05) by the grapefruit juice. Grapefruit juice postponed the tmax of diazepam from 1.50 h to 2.06 h (P<0.01).
 
ime it works best taken 20-30 mins prior
similarly with alprazolam

If anyone is interested (and has access to a Uni library) here is an article on potentiating diazepam with GFJ.


Interesting that they administered the GFJ and the valium simultaneously. I wonder if the effects would have been and different if the GFJ was consumed 30-45min prior (as most sources online seem to indicate as the way to go).

[/B]
 
You sure it was 2mg temazepam? 2.5mg sounds pretty low.... especially as 10mg temaz is equiv. to 5mg diazepam.

Woot, woot, you're light-weight like me! =D Eveyone I know (inc. BL) take ~100+/- to get a high off temaz. I personally have never found it to be recreational (of course - each to their own! =D ) - works perfect in a medicinal sense (for me) as a sedative but that's it! :\ (Maybe I haven't given it enough of a chance...although tbh I prolly don't want to go down that path again! Took me a while to get outta the benzo trap! :( )

Reckon that max I've taken would be 15mg, and that was for a comedown to knock me to sleep! :P Curiously, most other benzo's I sit pretty much exactly at the "medium dose" (as prescribed on BL/Erowid - maybe a little more due to the abuse a year ago!), just seems to be temaze which kicks my ass! Lol.


....
Regarding the 2mg temazepam; I have never seen these, do they actually exist in Australia? I have only ever seen the 10mg tablets, and they are the only dosage form listed on the PBS. There are 2mg diazepam, but prescriptions for them are getting rare and Roche has discontinued their 2mg Valium brand I believe.

I've seen 5mg and 10mgs, but personally not 2mg, either. Generally the dose instructions (for insomnia which is generally what it's first prescribed for) would say something long the lines of 5-15mg PO qhs. (with all the general contraindication of lower dosing elderly PTs, pregnancy, watch for poly-drug use, hepatic impairment....the usual)
 
Yeah I lost a few weeks on the stuff.

Even with accurate dosing phenaz probably wont be nice

Agreed J_P. If you know you're a very disciplined person, you should befine (providing you do use scales to measure your dose!)

...
So why is phenaz so potent, or is just that it often comes in powder form and people tend to eyeball it rather than weigh it?

Comes down to a very potent drug, which is active in extremely small doses and hence the dose-response curve it not very forgiving.

If this is the path you're going down (and you're generally experienced with other drugs), do all the right things to try to mitigate any negative situation which make arise, dose absolutely correctly (mg scales! and the like) and you should be fine! :)
 
Yeah I dont find that temaz that great to be honest. Even though I was pretty fucked up the other night, Ive had trouble sleeping on 40mg (20mg then another 20 a couple of hours later). Definitely better than nothing. Sometimes when I have benzos I have a tendency to rely on them too much (for sleep) and so Ill lay playing videogames waiting for sleep to overcome me. Doesnt always work out... you have to put some effort in yourself (even with alprazolam Ive had nights like that).
 
Lorazepam is my favourite benzos at the moment and i have access to all of them.
Only reason its not more popular is its like $50 for the 2.5mg ones and not on PBS

I know it was a while ago you wrote that d_F (July this year), but Im just curious what it was you enjoyed about it. And at what dosage. My friend got access to some Remedica Lorivan 1mgs and hey floated me 20. Turns out they were Lorivan 2s (bonus!)... dumb ass didnt even notice. Anyway Ill be trying tonight just having a chilled out night and see how they go.
 
In combinations with... ? Other benzos? I have some diazepam too if its worth combining them. I was saving the valium for codeine and for when needed for tapering/withdrawal minimisation type stuff.

I did however just have 4mg with a big glass of grapefruit juice. Also had a glass of GFJ 1hr ago and 30mins ago, so it surely have some sort of potentiating effect. (my expectations of potentiation are obviously an issue though... especially with a benzo Im not familiar with). Ill do a GFJ experiment with diazepam over the weekend. I have a fair bit of experience with diaz so any subtleties should be more apparent to me.
 
^ Sorry should have gone on there. In combination with opioids or for comedowns it is great, or even just by itself. I don't like to combine benzodiazepines, the only time I tried it was with lorazepam and alprazolam and I felt as though the alprazolam over powered it.

As always, when mixing CNS depressants be careful. :)
 
Yeah I thought thats what you probably meant. Easiest way to get a stupid answer is always to ask a stupid question.

My benzo resource isnt so expansive anyway. You make the best use with what youve got.
 
Successfully made a Phenazepam solution today :) wasn't as difficult as I thought it was going to be.

Added 100ml of Propylene glycol to 100mg of phenazepam powder in a pyrex dish. Let it sit for a while, stirring it every so often...didn't seem like much was dissolving. Decided I wasn't going to be patient today and put it on the gas stove on lowest heat, kept stirring it...soon I saw the little white crystal/powder bits start to disappear. When I noticed a tiny amount of steam coming off the solution I took it off the heat and placed the pyrex bowl in some cool water in the sink to cool it off (not sure what the danger temperatures are for phen or PG, but steam isn't normally welcome when working with precise amounts)

Kept stirring it, and within about 15 minutes the phenaz had completely dissolved. Let it cool down and then used a syringe to measure it into a small plastic bottle with dripper tip, ended up with 99ml. Not bad. Added an extra ml just because I like numbers that end in 0.

1mg per ml seems to be a good ratio. PG tastes kind of sickly sweet and gross, hopefully this will make me think twice when I'm wanting an extra dose.

Dosed 0.5mg and can definitely feel it. Nothing mindblowingly awesome but it's calming and making me feel a little sleepy.
 
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27mg etizolamm later.... 7days haze.... 2 car accidents....

Lesson to be learned here is. DONT DO 27mg etizolamm in one week...

atm my car is stranded somewhere with both front tyres flat... hit a curb at 60km or so... hopefully no further damage.
got a cunt of a mission today to go and fetch the car
 
shit mate that sucks. hope there aint any furthur complications ^^^

obtained some mirtazapine, but not having any luck with the info i want. many of you guys experienced tbis? what kind of dosage is involved for both proper and recreational use. what other side effects have you noticed after use, particularly in the following days of dosing? anything else i should know would be appreciated. peace
 
I stole my mothers pack of Valium pills, i think they were only 2mg pills. I took em all over like 2-3 days but didnt get any great effect from them, maybe they were just too weak?
 
shit mate that sucks. hope there aint any furthur complications ^^^

obtained some mirtazapine, but not having any luck with the info i want. many of you guys experienced tbis? what kind of dosage is involved for both proper and recreational use. what other side effects have you noticed after use, particularly in the following days of dosing? anything else i should know would be appreciated. peace


The only thing slightly recreational about it is mixing it with opiates. Other than that it is garbadge, good for sleep though. 15mg should be enough to sleep for around 16 hours. Be warned it will be pretty uncomfortable if you don't sleep when it hits. I am pretty drowsy the next day as well as very, very hungry.
 
The only thing slightly recreational about it is mixing it with opiates. Other than that it is garbadge, good for sleep though. 15mg should be enough to sleep for around 16 hours. Be warned it will be pretty uncomfortable if you don't sleep when it hits. I am pretty drowsy the next day as well as very, very hungry.
Before i was on my anti-depressant Avanza (which helps me sleep massively) i use to take Restavit, Restavit has i think Doxylamine...that shit in Mersyndol Night strength that makes you tired. Each pill has like 25mg, i use to take 2 and it would knock me out in less then 30mins...The next day though you wake up feeling like shit, like all groggy, not a nice experience but you do get sleep!
 
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