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Snorting vs Oral

E

enkephalin

Bluelighter
Joined
Mar 1, 2002
Messages
41
Location
seattle
A quick question about what is more effective. Is snorting a drug always more efficient then taking it orally, or does it just have a faster absortion rate? Also, I'm not talking about vics or percs that have a lot of tylenol in them, I'm refering to more coke, pure pain meds (no apap), adderall etc...
 
Been having a bit of a debate with my chums regarding this with pure oxy... they're all big snorting fans, but the whole process seems violent and painful to me, never done it. I downed 15mg just by chewing it up and drinking.. and had a good buzz going strong for 4 hours. Had a friend snort 15mg and an hour later he was already lookin for more. Dunno, maybe it's just me...
[ 24 February 2003: Message edited by: Merlin744 ]
 
id like to see the benefits of oral absorbability, when drug is placed under the tongue, being addressed. I *hear* this is the most effective way to take ANY drug.
[ 24 February 2003: Message edited by: CuriousCub ]
 
The problem with snorting something like oxy is it all doesnt absorb, some gets stuck in your nose, so oral administration is MUCH more effective.
 
The efficiency is determined on the livers role of metabolising that drug... for instance heroin is almost completly broken down by the liver... A 40mg oral dose of diacetylmorphine is equivalent to around 5mg insufflated.
But then a drug that isnt metabolised by the first pass of the liver is just as effective orally as it is snorted. A good example is oxycodone.. However, some oxy is metabolised in the first passed, and its more rapid pass in the system makes snorted oxy slightly more potent..
I'd say a snorted OC 20 is the equivalent of 25mg oral OxyIR. However, while snorting allows faster entry into the system, it also means faster leaving.. Snorting oxy probably takes 30min to an hour off the high.
I usually go oral on most things, unless i only have a small amount and i want to get the most out of it.
 
what about oral --placing under the tongue, not swallowing--for administering ketamine? would that be worthwhile?
 
sublingual, or under your tongue is by far the next best method after IV. Some drugs like heroin or buprenorphine lose upto 40% of their bioavailibility when going through the oral route. As long as you dont swallow the saliva too quickly when u have a tab under the tongue then its a better method than snorting.
 
Originally posted by CuriousCub:
drug is placed under the tongue, being addressed. I *hear* this is the most effective way to take ANY drug.
[ 24 February 2003: Message edited by: CuriousCub ]
The most effective way to take most drugs is IM or IV, depending on the drug
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of the two methods specified, oral is better in my opinion. It may not be as intense as nasal, but it lasts a lot longer. I'd rather be nice and numb for a few hours rather than rubbery for just one.
[ 24 February 2003: Message edited by: White Flag ]
 
Sublingual is more effective than snorting -- greater surface area of mucuous membranes, and you have gravity working FOR you not against you.
[ 24 February 2003: Message edited by: Negro-kitty ]
 
It's really depends on a few things...
1) The drug itslef - drugs like Valium (or any benzodiazepines) are best just eaten (or is it ate?) While drugs like Oxycodone are best snorted...
2) The high you're after - if you cruash an OxyContin, put it ina cap,and eat it, then you'll recieve a high where you come up more gentle and it will last longer - snort it and it hits hard but doesnt last as long...
3) Some drugs you just shouldnt sort because they burn with the fire of 7 suns - takeDarvon for instance (Darvocet sans the APAP - little caps with nothingbut propoxyphene in them).... eat like 5 of the 65mg caps andyerstraight.... try to rail one and you will be in tears for awhile...
Try each router, see what works best for you...
//p
 
benzos arent taken up by the mucous membranes in the nose, correct? so you just have to wait for the drip for you to feel effects?
ive never railed a xanax but ive seen others do it and it didnt seem to hit them very quick.
 
Originally posted by nnh:
benzos arent taken up by the mucous membranes in the nose, correct? so you just have to wait for the drip for you to feel effects?
ive never railed a xanax but ive seen others do it and it didnt seem to hit them very quick.Correct, you're better off either eating them or taking them sublingually (let them disolve under yer tounge) ... but no, if you snort benzos they are NOT absorbed viathe musac membrane...the reason people claim it "hits faster" is most likely because it's been crushedto powder then inhaled, it drains down yer throat and is absorbed in the stomache...
//p
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Originally posted by PhreeX:
Correct, you're better off either eating them or taking them sublingually (let them disolve under yer tounge) ... but no, if you snort benzos they are NOT absorbed viathe musac membrane...the reason people claim it "hits faster" is most likely because it's been crushedto powder then inhaled, it drains down yer throat and is absorbed in the stomache...
//p
despite this, will you still get the same overall effect as if you had swallowed the benzo?
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If I remember correctly a trusted source told me that methylphenidate absorption drastically changes from one method to the other, orally you get about 10-30% of the methylphenidate on a regular novartis 10mg ritalin pill, whilst snorted you get anywhere from 15%-60%, but there are many variables and each person reacts differently, also ritalin tolerance develops faster when done nasally, and as you may know the effects quite difeer from one another (snorted vs oral), and the comedowns are also uncomparable.
 
Originally posted by The Young Geezer:
If I remember correctly a trusted source told me that methylphenidate absorption drastically changes from one method to the other, orally you get about 10-30% of the methylphenidate on a regular novartis 10mg ritalin pill, whilst snorted you get anywhere from 15%-60%, but there are many variables and each person reacts differently, also ritalin tolerance develops faster when done nasally, and as you may know the effects quite difeer from one another (snorted vs oral), and the comedowns are also uncomparable.
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Originally posted by The Young Geezer:get about 10-30% of the methylphenidate on a regular novartis 10mg ritalin pill, whilst
If I remember correctly a trusted source told me that methylphenidate absorption drastically changes from one method to the other, orally you snorted you get anywhere from 15%-60%, but there are many variables and each person reacts differently, also ritalin tolerance develops faster when done nasally, and as you may know the effects quite difeer from one another (snorted vs oral), and the comedowns are also uncomparable.As I said, it depends on the drug, this being an example.. now the tollerance thing... I'd have to look into that as tollerance isnt based on the method of administration but the effects of the drug - hell; snort, eat, bang or smoke an opioid such as oxycodone or morphine for 2 weeks then quit and suddenly it doesnt matter ..
//p
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It really depends on how much of the drug crosses the Blood/Brain barrier... For some substances, snorting increases the ratio; for others it doesnt...
You can snort 20mg diacetylmorphine or bang 12mg of it, or swallow 70 mg of it.... either way your brain is only gonna see around 10mg of it.
 
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