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Stimulants Snortin' Vyvanse and other amphetamines?

Axemancometh

Bluelighter
Joined
Mar 12, 2026
Messages
95
Location
Canada
Hey all,

I've been recently getting into putting amphetamines (lisdexamphetamine in particular) up my nose for a quicker inset than eating them outright. I noticed that the nasal bioavailability must be significantly lower than if I were to swallow the capsules. This means I'm liable to take more than I usually will - but is there a sort of dose regulation (I.E. use 1.5x/2x as much) that I should follow when doing so in order to prevent myself from accidentally exploding my heart?

Thanks.
 
I
Hey all,

I've been recently getting into putting amphetamines (lisdexamphetamine in particular) up my nose for a quicker inset than eating them outright. I noticed that the nasal bioavailability must be significantly lower than if I were to swallow the capsules. This means I'm liable to take more than I usually will - but is there a sort of dose regulation (I.E. use 1.5x/2x as much) that I should follow when doing so in order to prevent myself from accidentally exploding my heart?

Thanks.
It's because of how vyvanse is metabolized in the Liver. Vyvanse is designed to not be abused, so taking it orally is probably the way to go.

Adderall would be the way to go if your wanting to snort but it also is limited compared to speed.
 
Docs won’t proscribe me Bupropion, when I know metal health issues are dopamine related not serotonin- yet they tried me wish every SSRI under the sun and they made me worse.

Frustration set in made me take things into my own by own and after years searching, I’ve found source for LEGIT bupropion hydrochloride crystals. I’ve never ever Its changed my life. I don’t snort it every day - but when I do, it’s a rush!
 
Docs won’t proscribe me Bupropion, when I know metal health issues are dopamine related not serotonin- yet they tried me wish every SSRI under the sun and they made me worse.

Frustration set in made me take things into my own by own and after years searching, I’ve found source for LEGIT bupropion hydrochloride crystals. I’ve never ever Its changed my life. I don’t snort it every day - but when I do, it’s a rush!
I used to put Zoloft up my nose when I was getting script. I don't think I've ever felt a worse nasal drip in my life up until that point:ROFLMAO:
 
brother, you cant snort vyvanse, it only metabolises to amphetamine in your stomach, lisdex alone is a inactive molecule, please stop wasting your drugs
 
Docs won’t proscribe me Bupropion, when I know metal health issues are dopamine related not serotonin- yet they tried me wish every SSRI under the sun and they made me worse.

Frustration set in made me take things into my own by own and after years searching, I’ve found source for LEGIT bupropion hydrochloride crystals. I’ve never ever Its changed my life. I don’t snort it every day - but when I do, it’s a rush!
Careful. Buproprion burns like a mother fucker, which will eat away at your nose if you do this for too many years. And too much in a day can cause auditory hallucinations, nosebleeds & seizures.

I'm surprised they won't prescribe it to you though. They hand it out like candy where I'm at & even acknowledge that it's abuse-able.
 
Careful. Buproprion burns like a mother fucker, which will eat away at your nose if you do this for too many years. And too much in a day can cause auditory hallucinations, nosebleeds & seizures.

I'm surprised they won't prescribe it to you though. They hand it out like candy where I'm at & even acknowledge that it's abuse-able.
Are you based in the US?
 
brother, you cant snort vyvanse, it only metabolises to amphetamine in your stomach, lisdex alone is a inactive molecule, please stop wasting your drugs

This is not true. It is metabolized in your blood. You can totally snort it or even IV it, but it just doesn't work any better - at all.

They've done studies showing that IV lisdexamphetamine produces just as much "drug liking" effect as oral lisdexamphetamine, in comparison to a vast increase when injected using dexamphetamine.
 
Are you based in the US?
Yes.
Buproprion is often used here if you have depression that doesn't respond to SSRIs/SNRIs.

I snorted it when I was younger & desperate for something once in awhile. It definitely works. But it makes you feel like shit when it wears off.
And of course that burn is not something I'd wanna be doing long term.

It's crazy though, I once met this dude who had just gotten out of prison. And he traded me a big bottle of generic buproprion for a whole half ounce of weed. lol Glad some people find it useful for something though, cause it doesn't do shit for my depression honestly.
 
Careful. Buproprion burns like a mother fucker, which will eat away at your nose if you do this for too many years. And too much in a day can cause auditory hallucinations, nosebleeds & seizures.

I'm surprised they won't prescribe it to you though. They hand it out like candy where I'm at & even acknowledge that it's abuse-able.
There was a thread here not long ago with a guy that was addicted to compulsively snorting MASSIVE amounts of buproprion. It was quite the read, but now I can't seem to find it.
Can't imagine how he's doing about now if he never stopped. He was doing scary amounts of it instranasally, if I remember correctly.

Edit: Found it (I was looking all over the place, and turns out it was just replied to yesterday lol)
bupropion started abusing it need something safer
 
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