Opioids smoking/snorting oxy

[Warm'nFuzzy]

ok i know smoking oxy is generally frowned upon and bad for you. but i was wondering which gives a stronger rush? ive never smoked em but have sniffed.

so what gives a better rush? smoking or snorting? maybe up the pooper? ahahha im willing8)

 

[DustnRoses]

IME, smoking is a total waste. Up the nose is the fastest rush, and is how I used to take them about 80% of the time. But the difference in bioavailability if you chew them up and swallow is huge...

 

[Warm'nFuzzy]

what gives the hardest rush? im not gonna smoke em im prolly gonna sniff em. or should i chew them if thats better than sniffing?

 

[amapola]

Generally when people look for the most efficient high, they use the "Bioavailability" property. This is how much total drug gets into your system over the duration of the high and is expressed as a percent (with IV being 100%).
Bioavailability/Half-life MEGA Thread

However BA doesn't tell the whole story. The maximum concentration and time to maximum concentration (rush) is also an important aspect of how you dose your drug. Having a high maxC might result in a lower BA so you will get higher but for a shorter period of time.

So for oxycodone if you want the most out of the drug to get the highest BA you should take it orally, however if you want a better rush and to get a little higher just for not as long you should take it nasally. Vaporizing oxycodone requires lots of processing to extract it from the pill and then would likely result in even faster onset but much lower BA though I'm not sure.

 

[verso]

amapola has said it all, really, but I just want to reiterate that snorting oxycodone is not altogether a total waste as it is with something like xanax or klonopin; I like to take a little bit orally and put a little bit up my nose.

It's also important to note that whenever you snort a substance, a certain amount of it will drip down into your throat and into your stomach, so a certain amount of a substance will inevitably end up in your stomach anyway. They've found with users who insufflate heroin, for example, that they experience a second peak in morphine concentration after about an hour or so, suggesting that these users swallow a certain amount of the heroin that is then metabolized into morphine in the stomach and absorbed more slowly into the blood stream.

That's just my two cents.

 

[TheLostBoys]

My gf snorts oxy so she swears by it but ive never snorted so I cant say anything good or bad about that method. I chop mine up & throw it in some carbonated seltzer water & let it sit for 12 hours. I then drink it down & it hits me hard & its kind of a different high than chewing & swallowing. Its more of a mellow & smoother high with my method.

 

[ThePharmacist25]

Where can I find that?

Hey, where did you find this chart? That is a pretty cool powerpoint and Id like to read more about it.. Concentration is basically the BA? Or is it the total area under the designated line? Either way cool chart..

Generally when people look for the most efficient high, they use the "Bioavailability" property. This is how much total drug gets into your system over the duration of the high and is expressed as a percent (with IV being 100%).
Bioavailability/Half-life MEGA Thread

However BA doesn't tell the whole story. The maximum concentration and time to maximum concentration (rush) is also an important aspect of how you dose your drug. Having a high maxC might result in a lower BA so you will get higher but for a shorter period of time.

So for oxycodone if you want the most out of the drug to get the highest BA you should take it orally, however if you want a better rush and to get a little higher just for not as long you should take it nasally. Vaporizing oxycodone requires lots of processing to extract it from the pill and then would likely result in even faster onset but much lower BA though I'm not sure.