dopeboy615
Greenlighter
- Joined
- Mar 23, 2013
- Messages
- 10
what is the best way to do shake and bake besides IV. smokin or snort or i actually heard swallowing it works
shake and bake meth, i snorted some eariler and it was alright but I really wanna see what people's input on it for smoking it off aluminum foil, cause i got a little left and that is what I want to try to do with
The bioavailability of intranasal and smoked methamphetamine.
Harris DS, Boxenbaum H, Everhart ET, Sequeira G, Mendelson JE, Jones RT.
Source
Drug Dependence Research Center, Langley Porter Psychiatric Institute, University of California, San Francisco, CA 94143-0984, USA.
Abstract
BACKGROUND:
Patients in harm-reduction treatment programs are switching from intravenous to other routes of methamphetamine (INN, metamfetamine) administration to avoid risks associated with needle use. Relatively little has been reported about the bioavailability of methamphetamine when smoked or used intranasally.
METHODS:
Eight experienced methamphetamine users were administered smoked or intranasal methamphetamine concurrently with an intravenous dose of deuterium-labeled methamphetamine. Plasma and urine concentrations were measured for calculation of bioavailability and other pharmacokinetic parameters by noncompartmental methods.
RESULTS:
Methamphetamine was well absorbed after smoking or intranasal administration, with bioavailabilities of 79% after intranasal administration and 67% of the estimated delivered dose or 37.4% of the absolute (pipe) dose after smoking. Maximum methamphetamine concentrations occurred at 2.7 and 2.5 hours after intranasal and smoked doses. The elimination half-life was similar for intravenous (11.4 hours), intranasal (10.7 hours), and smoked (10.7 hours) methamphetamine. Clearance (272 mL x h(-1) x kg(-1)), steady-state volume of distribution (4.2 L/kg), and mean residence time (16 hours) of the intravenous dose were similar to previously reported values. Dextroamphetamine (INN, dexamfetamine) half-life (all routes) was 16.2 hours. Methamphetamine and dextroamphetamine renal clearances (all routes) were about 100 and 1100 mL x h(-1) x kg(-1), respectively.
CONCLUSIONS:
Intranasal and smoked methamphetamine are well absorbed. Although intranasal or smoked routes may decrease the risk of transmission of blood-borne diseases, exposure to methamphetamine and the possibility of drug-related complications remain substantial.
Smoking shake-n-bake is possibly the most dangerous method of ingestion.
As it likely has leftover reactants in the final product (specifically Iodic acid... the most potent mineral acid), exposing your entire respiratory tract to this chemical could have detrimental effects, especially if exposed repeatedly over a long period of time.
Remember Krokodil? Same idea. Different drug, but same reactants. Not something you'd want to ingest intentionally.
The least you could do would be to run some simple chemical extractions to help purify the product.
Also, I think substituting automatic transmission fluid (a very high flash point nonpolar solvent)
except the dangers of pressurized ammonia.
Be sure you water wash the freebase several times before turning to HCL salt. Then wash the HCL salt with anhydrous acetone to remove impurities, and discard the dirty acetone. Then dissolve the HCL salt in anhydrous alcohol, and recrystallize it (evaporate the alcohol) after discarding the insolubles.
Also, I think substituting automatic transmission fluid (a very high flash point nonpolar solvent) for xylene/coleman/whatever should make the shake and bake method much safer. Dare I even say safe if properly ventilated? ATF does not sustain a flame until heated past 400F, so if the lithium catches sparks it shouldn't make a fire.
I'd be interested if someone who does S&B could try a batch with ATF to confirm my theory and make sure the reaction still works well. S&B explosions are some of the worst publicity for drugs at this point, and if simply changing solvents could take most of the danger out of it, this would really help our community.
<rant>
And for fuck sake, take your meth orally and weigh the doses, and keep a dosing plan and stick to it. Smoking, snorting and eyeballing are the paths to hell
Despite all the myths and fearmongering, meth can be used perfectly safely if you treat it with the respect it deserves, use low oral doses, and you don't go chasing that peak high constantly. It is a dangerous drug, but the dose makes the poison, and the RoA makes the addiction.
</rant>