After hearing many contradicting opinions on how soon 5 htp can safely be consumed after rolling, I was wondering if taking a smaller than normal dose and then seeing if there are any mild warning signs before taking more might be the logical solution. If so, what would be good starting dosage and how soon after my roll and how should i decide whether to take more?
-
MDMA &
Empathogenic
Drugs
Welcome Guest! -
MDMA Moderators: Esperighanto
small dose of 5htp to decide if too soon after MDMA for full dose
- Thread starter joe456
- Start date
matt2012
Bluelighter
the absorbtion rate is not going to be great enough for you to even notice the first day or second day after taking 5htp. IMO taking it the day after rolling is not going to do a thing for your hangover. it is a cumulative thing. you need to take it for days and days for the effects to be seen.
you are not going to get any benefit from taking it the day after and there is a higher risk of problems if you do so...just wait a few days before you start back up again that way you are sure your are not causing more harm than good.
you are not going to get any benefit from taking it the day after and there is a higher risk of problems if you do so...just wait a few days before you start back up again that way you are sure your are not causing more harm than good.
Why will 5-HTP increase the risk of problems? With all due respect, this is bullshit. Firstly, you suggest that it will not be absorbed or make a positive difference. So, if it's not absorbed, why is it going to cause problems? Secondly, even if it was absorbed (I don't know the time of metabolism), I see no reason why it would make things worse.
I get tired of every single 5-HTP thread having some sort of toilet comment about how it could cause 'receptor downregulation' or 'more problems than it solves.' It's a legal supplement available in many stores. It's a natural precursor to serotonin - we have it in our bodies all the time, regardless of whether you've taken MDMA, supplemented it or not! A small amount of external 5-HTP isn't going to cause any problems. If you disagree, prove it.
@OP, As i'm sure you're aware, I'm pretty certain you'll be fine taking 5-HTP pre roll, during the roll and after the roll. Nevertheless, I'd avoid taking it directly before the roll (on the day) - just in case. Anytime during the roll or after is absolutely fine and if you feel it helps you, then do it.
Folley
Bluelighter
^ If it's not absorbed it floats around in the bloodstream until the kidneys filter it out. That puts extra stress on a very important function of your body.
You seem rather certain that 5-HTP can NEVER have negative effects, no matter when you take it. That is rather foolish, IMO. Plenty of people have reported that 5-HTP dulls their roll, and others have had to go to the hospital to be treated for Serotonin Syndrome. 5-HTP is NOT in our BODIES, I've said this many times before.... it's only found in the brain, and it's bioavailability when taken unnaturally is SHIT. This means much of it is wasted, being filtered out before it ever reaches the parts that matter.
Kind of childish.. "prove it!". Can you prove that 5-HTP is safe for everyone, all of the time?
You seem rather certain that 5-HTP can NEVER have negative effects, no matter when you take it. That is rather foolish, IMO. Plenty of people have reported that 5-HTP dulls their roll, and others have had to go to the hospital to be treated for Serotonin Syndrome. 5-HTP is NOT in our BODIES, I've said this many times before.... it's only found in the brain, and it's bioavailability when taken unnaturally is SHIT. This means much of it is wasted, being filtered out before it ever reaches the parts that matter.
Kind of childish.. "prove it!". Can you prove that 5-HTP is safe for everyone, all of the time?
Don't really want to start the discussion about 5-HTP again but here we go. Read this (http://www.life-enhancement.com/magazine/article/46-5-htp-facts-and-fiction) and maybe you will reconsider some of views.
First of all, you'll notice that 5-HTP is in both the blood and the brain. Secondly, I do not suggest that it will 'NEVER' cause negative effects, it's just highly unlikely - barely worth mentioning. Thirdly, how can 5-HTP dull a roll and then also cause SS in others? These are absolute polar opposites. If 5-HTP dulled a roll it would suggest a reduction in synpatic serotonin as this is the main neurochemical proponent of the MDMA high. As i'm sure you're aware, SS is characterized by an extremely high amount of 5-HT residing in the synapse. Cross these two together and you'll see it doesn't make sense that 5-HTP could cause both. 'Plenty of people' sounds like simple hearsay to me. Just like 'plenty of people' are dropping grams of MDMA in one night. Or like 'Plenty' of pills contain heroin. The drugs world is full of bullshit everywhere you look.
Also, If you read the Q&A you'll see that the oral bioavailablity really isn't as poor as you suggest and they even suggest that it's quite good.
Truth is, I can't directly prove it. But like the link says, there are over 5000 articles on 5-HTP. If it was really dangerous I'd imagine at least 1 study would report something that would completely eradicate the general consensus toward it.
I find it kind of ironic how we're all willing to consume a potent serotonin agonist (MDMA) and downplay its negatives, but then issue dangers about 5-HTP.