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Skiing on X?

Special J said:
Also, you're probably going to want to have an SSRI like Prozac on hand so you can end the roll early if you need to.
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Never having been in a situation where I wanted to end a roll early, I've never really thought about it, but I don't think SSRIs work that way, do they? I was under the impression most took several weeks to build up to the point where they work. As a point of interest, you take an SSRI and end a roll in like 30 minutes?
 
SSRI's are supposed to be able to end rolls almost immediately. It's about how their blocking mechanisms work on the serotonin system.


Don't get a false sense of security though, just because you take precautions. The whole ski/Ex idea is very risky. You're combining two dangerous things, and the risk is definitely going to go way up. Like drinking and driving. I expect there'll be another 10 or 20 posts hammering this point home. Like everything else in life, it comes down to how much risk you're willing to undertake for a given reward. That's why this site exists. People have basically already decided how much risk they're willing to take, and they're trying to find out how much they can do without crossing that line. Adrenalin junkies are willing to take much bigger risks than most people, because it's just worth it to them. And this will definitely be an adrenalin rush. But there's no denying that it's a lot more risky than most people would find acceptable.
 
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Special J said:
And don't get a false sense of security, just because you are careful. You're combining two dangerous things, and the risk is definitely going to go way up. Like drinking and driving. I expect there'll be another 10 or 20 posts hammering this point home. Like everything else in life, it comes down to how much risk you're willing to undertake for a given reward. That's why this site exists. People have basically already decided how much risk their willing to take, and they're trying to find out how much they can do without crossing that line. Adrenalin junkies are willing to take much bigger risks than most people, because it's just worth it to them. And this will definitely be an adrenalin rush. But there's no denying that it's a lot more risky than most people would find acceptable.
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Oh absolutely. I'm a gambler, risk taker, life on the edge type person. Like most things in life, greater risk equals greater reward. That said, i'm probably not going to do it, but I was curious to see if anyone else had that idea or had done it because it crossed my mind and sounded fun as shit. I haven't skiied in a few years and i'm nowhere near confident enough to try rolling and skiing. At least not right now.

That said, somewhere down the road I see it happening ;)
 
It should be mentioned that skiing will undoubtedly raise the body temperature, which of course is unwanted when dosing MDMA...
 
It's easy to stay cool, while skiing downhill, I'd be more worried about adrenalin pushing the heart too hard.
 
EpicurusFire said:
Alright you guys have pretty much failed at convincing me this is a bad idea. "They're both SO AWESOME by themselves, I wouldn't do it because it would just be TOO MUCH AWESOME AT ONCE!" is basically what i'm hearing.

Can't wait for this ski trip =D
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Clearly you completely fucking ignored every negative comment that was posted in this thread, which was more than half of them.
If you want to risk your own safety, that is up to you. But don't be a complete douchebag and risk the safety of innocent people who will be skiing around you. The guilt will only be on you if something bad happens. In my mind, it's not worth the risk.

Special J said:
SSRI's are supposed to be able to end rolls almost immediately. It's about how their blocking mechanisms work on the serotonin system.
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Please do not abuse psychiatric medications in this way.
 
n3ophy7e said:
Please do not abuse psychiatric medications in this way.
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Actually, the only reason I know it is because the SSRI is supposed to be healthier than just letting your roll end. It theoretically helps prevent neurotoxisity if you take it within the first 4-6 hours of your roll. So some people regularly end their rolls that way. Less of a comedown, etc. And one pill is not the same as taking them regularly.
 
I have never heard this before so I'd love to see some supporting evidence. Got any links to sources which can verify this use of SSRIs?
I ain't saying you're right or wrong, I'd just like to learn more about your theory :)
 
"Some studies suggest that possible MDMA-induced neurotoxicity to the serotonin system can be largely prevented by taking a double dose of fluoxetine (Prozac) or another SSRI shortly after starting to "come down". Post-E Prozac in particular mitigates the oxidative stress and consequent risk of serotonergic axon damage caused by reactive products of dopamine deamination. The long-acting SSRI Prozac/fluoxetine, and its even longer-acting metabolite norfluoxetine, apparently prevents the uptake of dopamine (and any toxic metabolite(s)?) into the serotonergic nerve terminals by binding to the serotonin reuptake transporter with higher affinity than MDMA or serotonin."

http://www.mdma.net/#ecstasyprotect

And...

The time course of damaging events in rats can be seen by administering SSRIs, such as fluoxetine and citalopram, after MDMA. Pretreatment with fluoxetine (Prozac) or citalopram (Celexa) has been shown to block the neurotoxicity of MDMA (Battaglia, 1988; Schmidt 1987; 1990; Shankaran, 1999a), probably by blocking interactions of MDMA with SERT. More interestingly, fluoxetine remains almost fully protective if given 3 or 4 hours after MDMA. By 4 hours, most of the MDMA-induced release of 5-HT and DA has already occurred (Gough, 1991; Hiramatsu, 1990) and increases in extracellular free radicals (Colado, 1997b; Shankaran, 1999a) and lipid peroxidation (the alteration of fat molecules by free radicals) (Colado, 1997a) can be measured. Nevertheless, the administration of fluoxetine at this point decreases subsequent extracellular oxidative stress (Shankaran, 1999a) and long-term 5-HT depletions (Schmidt, 1987; Shankaran, 1999a). Fluoxetine will still be partially protective if given 6 hours after MDMA but has no protective effect 12 hours after administration (Schmidt, 1987). This shows that neurotoxic MDMA regimens initiate a series of events that become increasingly damaging between 3 and 12 hours after drug administration in rats.

http://www.erowid.org/chemicals/mdma/mdma_neurotoxicity1.shtml#timecourse



There's been more that just one study, but it's still just a theory, and most of the research has been done on rats. We don't know a whole lot about the 'damage' ecstasy does in general. But some people see the possible safety benefits as sufficient reason to take an SSRI (especially prozac) after MDMA. Throw in the fact that they can sometimes be used to abort a roll, and there's definite potential there. It would be more of a solution for people who roll very occasionally and are just looking for possible ways to be a little safer.
 
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