I find the two similar but also VERY different:
4-ACO-DMT: friendlier, easier on the mind, visuals are swirly van gough like and less "crisp", more colorfull (lot's of pinks, reds, and greens), lot's of humor but less so than mush, impaired motor control and almost dissociating in high doses, lasts 1 hour less for me, slightly more morphing and water-like visuals, rougher come-up, more sedating, and more forgiving dose for dose.
Mushrooms: Stronger emotional opening, strong effects on thoughts, more complex and geometric visuals (lot's of greens, aqua blues, purples, browns, and blacks), stronger CEV's but less OEV's (not every time though), extremely variable between experiences, heavier bodyload, slightly longer lasting, less forgiving, lot's of humor and giggle fests.
Keep in mind that effects are extremely variable person to person and what I or anyone else feels on these substances means very little on how you will feel. Personally though I would rather have psilacetin but that's just me, it's cheaper, more enjoyable (subjective), has less bodyload, less variable experience to experience and I prefer working with powders. Without a doubt though I would be able to differentiate between the two in a double-blind study, no doubt.