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Shrooms fighting with Risperdal/risperdone...
- Thread starter spass
- Start date
Vaya
Bluelight Crew
I see people aborting trips with 1.5, 4 and 5mg risperidone (Risperdal). To me, anything above 1mg is a "high dose."
I've been rx'ed 0.25mg risperidone BID (so 0.25mg in the morning, 0.25mg at night) for the past 4 weeks. Four weeks ago, I took two tabs of LSD and tripped quite nicely.
Tonight, at around 10pm I took my nightly 0.25mg risperidone. 2 hours later, at midnight, I dosed a 5-strip of some quality-tested (and *high* quality, at that...) LSD blotter.
And I don't feel shit.
Could the sheer *power* of risperidone be that it can prevent the advent of a high-dose psychedelic experience when it itself has been taken, albeit quite prior to the administration of psychedelics, at the lowest prescribed dose available?
Gracias,
~ vaya
I've been rx'ed 0.25mg risperidone BID (so 0.25mg in the morning, 0.25mg at night) for the past 4 weeks. Four weeks ago, I took two tabs of LSD and tripped quite nicely.
Tonight, at around 10pm I took my nightly 0.25mg risperidone. 2 hours later, at midnight, I dosed a 5-strip of some quality-tested (and *high* quality, at that...) LSD blotter.
And I don't feel shit.
Could the sheer *power* of risperidone be that it can prevent the advent of a high-dose psychedelic experience when it itself has been taken, albeit quite prior to the administration of psychedelics, at the lowest prescribed dose available?
Gracias,
~ vaya
Vaya
Bluelight Crew
^unlikely, my friend... Risperidone is one of the most potent 5HT2 antagonists, which explains why it is capable of being used effectively to "abort" psychedelic experiences on drugs such as LSD, a potent 5HT2 agonist...
Hence my question as to why, despite such a low relative dose of risperidone (0.5mg/day vs. others' 1.5-5mg/day!), 5 hits of high quality blotter essentially went down the tubes last night
~ Vaya
Hence my question as to why, despite such a low relative dose of risperidone (0.5mg/day vs. others' 1.5-5mg/day!), 5 hits of high quality blotter essentially went down the tubes last night
~ Vaya
Vaya
Bluelight Crew
Update last risperdal 0.25mg taken at 10:00pm last night... 5 100ug tabs taken at 11:45pm - slight bodily stimulation absolutely nothing more.
Skipped this morning's 8am 0.25mg risperdal, dosed on two 250ug tabs at 9am.
Time now = 10:45am and I'm just.... Fantastically trippin' the light fantastic. Wow. Got the answer to my original ? - a mere 0.25mg risperidone was indeed more than enough to totally nullify 500 mics of acid. But no more, no no that's not where were at NOW....................
Skipped this morning's 8am 0.25mg risperdal, dosed on two 250ug tabs at 9am.
Time now = 10:45am and I'm just.... Fantastically trippin' the light fantastic. Wow. Got the answer to my original ? - a mere 0.25mg risperidone was indeed more than enough to totally nullify 500 mics of acid. But no more, no no that's not where were at NOW....................
rollingstoned!
Bluelighter
5-HT2A agonists are cross-tolerant with 5-HT2A antagonists.
Yeah you read that right...they both downregulate the receptor. Obviously one activates it while one doesn't.
Yeah you read that right...they both downregulate the receptor. Obviously one activates it while one doesn't.
Well what I was asking, is it possible that taking a 5-HT2 antagonist would affect the symptoms brought on by LSD later in life and just 5-HT2 agonists in general.
I have never combined the two and certainly don't intend to. No the only thing I like with my LSD is good company, good environment, and a big bowl of weed.
I have never combined the two and certainly don't intend to. No the only thing I like with my LSD is good company, good environment, and a big bowl of weed.
Vaya
Bluelight Crew
I just want to report back - I was, really, in *no* shape to be typing (I'm not sure how I got the above post out, TBH) - but I was thinking the same thing as
...and what's stranger, I mean, the night before I got virtually no effect from the 500ug, but after skipping just one dose of risperdal, the second dose of 500ug had me going stronger than I was initially comfortable with - and I consider myself extremely well-versed with even the subtlest of LSD-related nuances. It was a strange, deliciously lush but powerful experience. Further research is *definitely* needed into this interaction between agonists and antagonists, and their respective dosing time-tables, for the 5HT2a receptor.
Veryinteresting bit of information, there. Does that work with all neurotransmitters? e.g. DA agonists would be cross-tolerant with DA antagonists, etc.?
Thanks! :D
~ vaya
...and what's stranger, I mean, the night before I got virtually no effect from the 500ug, but after skipping just one dose of risperdal, the second dose of 500ug had me going stronger than I was initially comfortable with - and I consider myself extremely well-versed with even the subtlest of LSD-related nuances. It was a strange, deliciously lush but powerful experience. Further research is *definitely* needed into this interaction between agonists and antagonists, and their respective dosing time-tables, for the 5HT2a receptor.
Veryinteresting bit of information, there. Does that work with all neurotransmitters? e.g. DA agonists would be cross-tolerant with DA antagonists, etc.?
Thanks! :D
~ vaya