This is how it starts lol...
Caffeine --> Alcohol ---> Nicotine ---> MJ ---> lsd ---> xtc --->
coke ---> speed ---> ice ---> heroin
IMHO
Psh, drug use can take one of many different paths.
Like almost everyone, I really like like ecstasy, MDMA.
But there are negative, long-lasting, after effects involving serotonin synapse destruction. If you use it every weekend, the negative effects are gonna SUCK. With ecstasy at those levels, depression really is almost unavoidable; something in MDMA (a metabolite of it?) is causing damage.
If you use MDMA too often, it will, at least, take longer for serotonin regulation to re-stabilize and feel 'happy' again. And that's--obviously--no fun! At worst they might not fully recover.
Who knows, research is still far from explaining everything about how it works. (However,
a new study on an alzhemier's drug called memantine seems to explain a lot of the mdma receptor activity. Don't get your hopes up on, though, it blocks the neurotoxicity AND the actual effects. It makes the MDMA not work at all.
For now, I'll take molly no more than 6 or 8 times a year and will only suffer a normal hangover and insignificant or non-existant SERT damage. At this level of use, I don't think I need to be too worried, as long as I keep taking my vitamins and 5-htp the days after.
But I really hope a new synthetic 'ecstasy' is developed in the future, without those nasty neurotoxins...it really is magik, and makes you feel alive, and to do use it more often, well, that would be divine. And would fix everything for everyone. :D