yes it can, im assuming youre talking about roxicodone? what i usually did was fill a 1cc syringe full of water, heated it to a boil, as soon as i saw bubbles i stopped heating it. waited one minute dropped the whole roxy in and let it dissolve. you can use cotton as a filter but beware of cotton fever, you can pull of the end of a q-tip, or my fave cut the end of a cig filter, and or a micron filter. the micron filter is the best filter you can get for this but it is not necessary but it does make the whole ordeal much much safer. so once its all dissolved put your cotton like filter in, and stir with the needle in the cotton. then draw through the filter, flick out the bubbles tie off. find a vein, pull back if theres blood youre good to push it in. if theres not blood you missed the vein and you can either pull out or dig around for it. but be very careful if you decide to dig around for it. if youre using a micron filter youll need two syringes. follow all the same steps up until drawing the finished product thru the cotton. instead draw the finished product in to a needless syringe, screw on the micron filter, push out the liquid into another alcohol cleaned spoon, but make sure the alc is all gone push the liquid into the spoon, take the needle, draw in the liquid and follow the last few steps. all you can get at a pharmacy is the insulin syringes they dont sell micron filters youd have to get those online. hope this helps. be very very careful this is a dangerous roa.. And as for acquiring the syringe, it may be easy or it may be hard dont look like youre a user of anything and simply ask the pharmacist for a bag of 1cc 28gauge insulin syringes for novalog. or however you want to try and obtain it. either way, its at the pharmacists discretion to sell or not to sell