Never had any problem getting blasted into the stratosphere by 100mg of 5x, a torch lighter, and a bong. Maybe it helps to pay a little more for the standardized extract? I love S. divinorum, although I'm in the minority among my friends who have tried it; they all freak out and find it to be a terrifying experience.
I always feel like I'm transported "behind the scenes" of the physical world, like my soul departed from my body and personality, returning to the ether... I forget who I am and have been during this lifetime, and just "am". I often sense other souls around me as well, and it is always a very welcoming, ecstatic experience. It's the most bizarre and intense sense of familiarity, of "coming home" if you will, from the first time I tried it. Strange, especially considering I don't even believe in the existence of souls, but the feeling I get from Salvia seems somewhat compatible with the concept of reincarnation.
It's also strange, because it's the ONLY drug I've tried that has any sort of spiritual slant for me at all. Maybe because only with Salvia I am able to experience enough ego loss to let go of myself and open up to that kind of thing. I still feel fairly grounded on mushrooms, LSD, and MDMA, whereas Salvia completely obliterates the concept of reality.
DMT was mentioned... I can't wait to try that, I should have some within a few weeks. Although I suspect I'll enjoy it (I've never met a psychedelic I didn't like), perhaps more than Salvia, I don't think it could ever replace it.