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Misc Safely potentiating opiates with benzodiazepines

phantomcosmonaut

Bluelighter
Joined
Dec 24, 2011
Messages
277
So I recently obtained 10mg oxycodone pills (Roxicodone) and 1mg clonazepam. I have heard it is unsafe to mix benzos and opiates but people also do it all the time. I have previously done 15mg hydrocodone, ~2mg xanax and 50mg benadryl and I was fine. I should also add that I have no tolerance and that is the second time I've ever done an opiate, I also do benzos like once a month, maybe less. So would 2mg of clonazepam and 10mg oxycodone be safe and enjoyable? I also did 10mg oxycodone once 2 years ago and i got very little to no effects. Dosage recommendations would be nice or any input really, thanks.
 
If I were you, I'd go heavier on the oxycodone and completely leave out the clonazepam. You have no tolerence to either drugs so it won't take too much to get desired effects. Try 25 mgs of oxycodone and then see where you are at.
 
There really is no way to "safely" potentiate opiates with Benzos, even 5mg of Valium might push you over the edge. Best to try them each on they're own to judge what the effect will be combined. Play safe!
 
^This. You can safely mix them - but only if you're smart about it. See how 20mg oxycodone feels by itself (and see how 1mg clonazepam feels by itself) before mixing them. If you do decide to mix them, reduce the dosages of both drugs.
 
If I were you, I'd go heavier on the oxycodone and completely leave out the clonazepam. You have no tolerence to either drugs so it won't take too much to get desired effects. Try 25 mgs of oxycodone and then see where you are at.

This, it's not safe for beginners to be mixing CNS depressants, especially benzodiazepines with opioids, the risk of accidental overdose and fatal respiratory depression is so high, it's not worth risking. What you should do is just take more of your drug of choice, slowly titrating until you're at the level you want to be. Adding in benzodiazepines is a horrible idea, it's too dangerous for someone who isn't very tolerant to both classes of medications.

YMMV, everyone's body is different so what's safe for some, is incredibly dangerous for others. Don't mix opioids with benzodiazepines. If you're honestly considering doing it because people "do it all the time" then you should take a few steps back and look at how flawed your logic is. You know what people do all the time on this combination of drugs? Overdose and/or die.

You have next to no tolerance anyways, not tolerant to opioids, not tolerant to benzodiazepines. To be safe, abuse these medications separately, be mindful of their half-lives and mechanisms of actions.

TL;DR Chances are, if you have to make a thread about this online to ask, you don't have the tolerance to be considering this. And, if you have a speck of genius in you, you will find another safer way to enjoy yourself ;) .

Some people regularly mix the two medications, as they have been directed to do so by their prescribing physicians, and the doctor there has weighed the benefits vs the consequences. It's still dangerous, accidents happen, and even taken as prescribed, bad things can happen if you aren't extra careful. These are incredibly potent CNS depressants, please respect them and treat them as such. They each synergize together very strongly, when combined the risks are exponential.
 
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This, it's not safe for beginners to be mixing CNS depressants, especially benzodiazepines with opioids, the risk of accidental overdose and fatal respiratory depression is so high, it's not worth risking.

Sometimes, not even for the experienced. I was mixing the two regularly, then one day... bam, wake up in ICU three days later cause I od'd. There are a lot of potential things that can go wrong, even besides the respiratory depression. You might be so out of it you do something incredibly dangerous. Like most people have said, if you have no tolerance, enjoy it while it lasts (cause it wont). I feel as though most people mix the two cause there tolerance is so high, they're trying to do anything to save money / catch the buzz they use to feel when they were opiate naive, etc. That's why I mixed the two.
 
So I recently obtained 10mg oxycodone pills (Roxicodone) and 1mg clonazepam. I have heard it is unsafe to mix benzos and opiates but people also do it all the time. I have previously done 15mg hydrocodone, ~2mg xanax and 50mg benadryl and I was fine. I should also add that I have no tolerance and that is the second time I've ever done an opiate, I also do benzos like once a month, maybe less. So would 2mg of clonazepam and 10mg oxycodone be safe and enjoyable? I also did 10mg oxycodone once 2 years ago and i got very little to no effects. Dosage recommendations would be nice or any input really, thanks.

I wouldn't mix them at all, just take the Oxy. For someone without a benzo tolerance, 2mg Xanax just seems like overkill. Even 1mg Klonopin is just way too much. You gotta take into account that combining 10mg Oxy and 1mg Klonopin doesn't feel like each drug normally does... The effects of each drug are greatly pronounced, and things could go badly pretty fast. Take care!
 
I had been taking opiates for 2 years. I talked to my dr about my anxiety and he gave me 2mg Xanax. 1/2 in the morning. 1/2 in the evening. On my first day I took 1 norco 10/325mg and then 1mg Xanax. I blacked out. I was mean to my family. I went down stairs and passed out. I don't remember how I got on the couch. I woke up with my step daughter asking me what happened. I had no idea. She filled me in.
 
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