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Safe to roll? Very inexperienced

pnillyg

Bluelighter
Joined
May 3, 2024
Messages
681
Hey fam… I’ve been taking oxycodone 15ish mgs for the last week give or take and stopped yesterday. Very minor withdrawals (so far). This morning i did 30mg cocaine and didn’t have much effect. I’m wondering if it’s safe to roll this evening with my girlfriend and how much. I’m super inexperienced with MDMA i have a brownish type crystal. I also do take Lunesta most nights as well including last night along with 4mg zofran. Thanks for looking out!
 
If you've got good nights sleep, oxy withdrawals do not present any remarkable risk to health in conjuction with administration of MDMA-it could even fix the bladder lock associated to molly :D Theoretically if you feel like total shit and haven't slept, it could expose to bad trip or psychosis but that does not seem to be the case.

Zopiclone is fine but as I read about ondansetron, it seems bit concerning. I am just now trying to figure it out, but if I do not come back to the topic you shall assume I am so lethargic of mirtazapine that I could not understand complex pharmacology anymore and can not help anymore.



 
So, I didn't find anyone telling that they had SS for administering molly on ondansetron but I found this article with conclusion that claim ondansetron exposing to risk of SS is false. Which makes a lot of sense. Apparently claim was based on few anecdotal reports which led to hypothesis that antagonizing peripheral 5ht-3 receptors with ondansetron leads to excessive serotonin to agonize 5ht-1a receptors, leading to serotonin toxicity, which seems like a stretch even in theory and apparently also has no proper evidence of really leading to any remarkable issues.

 
If you've got good nights sleep, oxy withdrawals do not present any remarkable risk to health in conjuction with administration of MDMA-it could even fix the bladder lock associated to molly :D Theoretically if you feel like total shit and haven't slept, it could expose to bad trip or psychosis but that does not seem to be the case.

Zopiclone is fine but as I read about ondansetron, it seems bit concerning. I am just now trying to figure it out, but if I do not come back to the topic you shall assume I am so lethargic of mirtazapine that I could not understand complex pharmacology anymore and can not help anymore.




So, I didn't find anyone telling that they had SS for administering molly on ondansetron but I found this article with conclusion that claim ondansetron exposing to risk of SS is false. Which makes a lot of sense. Apparently claim was based on few anecdotal reports which led to hypothesis that antagonizing peripheral 5ht-3 receptors with ondansetron leads to excessive serotonin to agonize 5ht-1a receptors, leading to serotonin toxicity, which seems like a stretch even in theory and apparently also has no proper evidence of really leading to any remarkable issues.

im so glad i added the zofran in... i forgot when i posted at first thank you so much for the info. definitely going to wait. not worth the risk.
 
im so glad i added the zofran in... i forgot when i posted at first thank you so much for the info. definitely going to wait. not worth the risk.
Also is there kratom interactions? I’ve seen people mix but I’ve also heard there is antidepressant properties of kratom that could potentially lead to SS?
 
Also is there kratom interactions? I’ve seen people mix but I’ve also heard there is antidepressant properties of kratom that could potentially lead to SS?
Hi mate,

To the best of my knowledge, there shouldn't be any issues with that combination, however, it may be best to wait for @Pissed_and_messed opinion to confirm this, as it's not something I am willing to confirm without a second opinion (for HR, of course)

A.T
 
kratom has some SSRI qualities which should not be problem, as we have pretty much concluded on another thread about topic. I have heard some anecdotal reports about kratom causing some kind of issues in conjunction with other serotonergic drugs. I can not make any final conclusion about matter. But most likely than not, you'll be fine.
 
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