Safe to potentiate Hydrocodone with these?

[Brian242]

30 minutes before initial 15 mg Hydrocodone dose .

Chew 2 Tums, and 220 mg ibuprofen.

Yay or Nay?

 

[verso]

I'm not sure how much a couple tums and some ibuprofen will potentiate anything at all, so uh... yeah, I would say that you're in the clear, my friend.

 

[BrokedownPalace]

While it is certainly safe to take tums and ibuprofen in conjunction with hydrocodone, it will NOT potentiate your high.. Potentiation is done by inhibiting certain enzymes responsible for the metabolization of the drug in question. Ibuprofen may add to the pain killing effect, but it certainly will not add to the 'high'.

Check out the following thread - The Ultimate Opiate potentiation Thread v2.0, for a list of common potentiators of opioids.

 

[Seattle_Stranger]

Try cimetidine or a tall glass of grapefruit juice. Works like a charm, especially with hydrocodone. I take 400mg cimetidine religiously with any opiate I take. I'm convinced it results in a much stronger high. It also might help with some accompanying nausea that may result from the opiates.

Another cool thing I've found as of yesterday, is that ranitidine (Zantac) also works.

 

[hydroazuanacaine]

can't be said better than BrokedownPalace's post.

Brian242, if you are asking about ibuprofen in conjunction with hydro for pain, PM me about re-opening this. it will not add to the high though--for that check out BDP's post.