Safe prep technique for wax sustained release tablets

[fastandbulbous]

OK, time to do some information sharing...

I was given a couple of 100mg MST tablets (sustained release morphine sulphate tablets) a while ago. They are sustained release because the morphine sulpate is distributed throughout a wax matrix; this incidentally makes them dangerous for people to prepare for injection. Now the fact that I'd been given a couple meant that I had a chance to experiment on ways of separating the morphine sulphate from the wax in the hope of finding a simple, easy way that left behind a product safe for injection.

Previously, I had found that either methylene chloride or chloroform had acted as a suitable solvent for the wax, but these are both highly unpleasant solvents, so don't really fit the bill. Alcohols will not dissolve the wax, so the list of possible solvents was very limited. As they say,'all things come to he who waits' and I thought I'd share my finding; benzene worked beautifully, but as it's also implicated in bladder cancer, that was a no go, but toluene will dissolve anything that dissolves in benzene. As it's fairly easily available, it works wonders as follows:-

1/
Remove the outer coating of the tablet so all that's left is the wax/morphine matrix

2/
Using a glass container, add the morphine/wax, break into small pieces, then add 5ml of toluene for every pill

3/
Place the glass container into another container and add enough hot (not boiling) water to the surrounding container to create a hot water jacket around the glass container, and stir gently until all that is left undissolved is a fairly fine white powder that sits on the bottom (about 10 mins).

4/
Leave to stand for a while, then pipette off as much of the toluene as possible, taking care that you suck up as little of the white powder. Put the toluene removed into a glass jar or similar.

5/
To the glass container (now containing a white powder and a small amount of toluene), add the same volume of ethanol or isopropanol. Give it a quick stir, let the contents settle and then remove the alcohol. Repeat again.

6/
Stand in a warm place to allow the rest of the alcohol to evaporate. The dry powder left is pretty much pure morphine sulphate.

As a test that the wax has been dissolved by the toluene, add a few drops to 10ml of alcohol - it will go cloudy as the wax is precipitated out (just like adding surgical spirits to water). This works as morphine sulphate is insoluble in both toluene and alcohol. The purpose of the alcohol washes are to remove the last traces of toluene (it's better than benzene, but still not a 'nice' solvent).

The dry powder is suitable for either snorting or reconstitution to a perfectly clear solution, which after passing through a micron filter, is suitable for injection.

If using a lower dose tablet (60mg, 30mg etc), you may need to use a little more toluene, as there'll be a little more wax in the tablet.

Hopefully, this method will allow someone who is determined to inject MST tablets a way of doing it without endangering their lives because other methods also result in some wax ending up being injected (this is after all a harm reduction site)

PS. It'll also work for wax matrix oxycodone tablets as well.


Lets do things safely people

 

[fastandbulbous]

Possible source of error - I don't know how soluble oxycodone salts are in alcohols, so it might not be applicable for them. I'll get back to this particular glitch after I've found info on the salts used and their solubilities

 

[chasem]

it would be neat to change this to dia-m w/ AA

 

[101]

PS. It'll also work for wax matrix oxycodone tablets as well.


Lets do things safely people

Isn't oxycodone freely soluble in alcohol? would that effect the process any?

Sorry didn't read the rest of the posts.

 

[fastandbulbous]

^ It's the salt used that's important, a tartrate or hydrochloride salt would be dissolved ( to some extent) by the alcohol, rather than the alcohol just washing off the toluene; that's why sulphate or phosphate salts are best, they're generally nigh on insoluble in alcohols

 

[Juggalotus]

So, with a little bit of sulphuric/phosphoric acid, could one turn Oxycodone HCL into Oxycodone sulphate/phosphate?

If so, it sounds like a bit of work to me... Just a thought though, for those people who have that much time on their hands. I wish I did .

 

[fastandbulbous]

After a bit more thought, I'm prepared to revise my original statement, and say that it should only be used for MST/MS continus. Still, considering how many of those little buggers seem to be going around, it's still fairly useful

 

[xspikehead]

Yea, well this is a good way to extract morphine sulfate and clean it up enough to easily convert it to morphine HCl, a product with a much higher bioavailability.

 

[fastandbulbous]

By which route? Oral availability is mostly controlled by 1st pass metabolism, and whether the salt was a sulphate or a hydrochloride does not alter the amount of morphine metabolized. The only route that it would have any significance in would be if you tried to smoke/vapourize the two salts

 

[101]

After a bit more thought, I'm prepared to revise my original statement, and say that it should only be used for MST/MS continus. Still, considering how many of those little buggers seem to be going around, it's still fairly useful

Wait, does this mean that doing an alcohol extraction on oxycodone would not be the best way to go? Would it leave you with wax in the final product?

I've always been under the impression that doing an alcohol extr. would be best for oxycontin.

 

[pokin' canadian]

hey all, sorry to bump this thread up but hte reason is two-fold

first off, i think this thread is really usefull and should be up near the top

second of all, i think that its a great idea and am in the middle of cleaning up a dose of morphine er for tomorow morning, i hope it works

what i appear to have so far is (now) a small amount of toluene left on the bottom of my beaker with an amount of wet powder.....i can only assume that this powder is pure morphine sulphate wetted with toluene....thats all it could be......

anwayys, my wonder is, can i soak up the remaining toluene with cotton before i go and do the alcohol washes? my reason for wanting to do this is to get rid of AS MUCH of the toluene as i can before i even try washing it, thus washing should be more effective/easier. my worry is that somehow i will suck up some morphine. logic tells me this can't happen, however, since this whole process is based on morphine NOT being soluble in either isopropyl alcohol OR toluene, thus, i should be able to soak up anything i want and the morphine will simply stay in the beaker as powder, is this true? so long as i keep water out of the system, the morphine should remain undissolved. also, i think that toluene and water DO NOT mix, therefore if there is toluene left, i'm not sure that the morphine would disolve well anyways, although i guess it would, just in the water only

either way, will this saoking with cotton work, or should i just leave whats left and do a few alochol washes?

thanks for the info

bounce

 

[ChemicalSmiles]

Too much work IMO. Rather get some dope or something more soluble.

-weez

 

[pokin' canadian]

you'd rather get some "dope" or something a little more soluble eh....morphine isn't good enough? morphine is basically heroin (or dope, if you can't use more than four letter words), with a little "better" of a rush, but to be honest, for the money, heroin is a big, fat, waste. I take so much M in a day that a heroin habit would just be retardedly expensive, especially when it costs over 120 bucks for a half a gram of pretty crappy heroin.

oh, i failed to mention, i get 100mg M-Eslon (basically mscontin with less wax) scripted to me, the government pays for almost all of it, and what they dont insurance does. so put it this way, i pay almost nothing, like around 50 bucks a month for a dope habit that, on the street, would cost about that per day, if i was to stick to M but off the street. H, on the other hand, would cost me well over 2-300 bucks a day, and this is making about that in a week, at the most.

you tell me what you would do now, if you had the choice. you can either shoot heroin for a few weeks until you are more broke than ever, lose your home and everything else you own, and then when you run out of money either go to the streets, or have to go through detox and then live a shitty ass live WITHOUT drugs because you had to get greedy and move on to heroin, good idea buds. now you've got nothing left, nothing to show for except maybe some track marks, and now you are stuck rebuilding your life.

OR you could take the M that the dr gives you, have your time with it, and get it refilled every month, on uncle' sam's tab....? hmm....this way, you can keep leading a normal life, have a girlfriend, have a home, have food on the table, a computer to browse these forums (although i wonder why sometimes with dumbshit ppl on all the time), and whatever else one may own. you can continue this on indefinetly, because chances are pretty good that when your tolerance builds, the doctor will be expecting that (albeit maybe not at such a high rate, but oh well, you have "a faster metabolism when it comes to morphine.....what can i do about that dr?" and you get your doseage upped. the biggest downside is always going to see the dr, and having him control wether or not you are sick. oh well, i can live with that fact considering i am spending a small fraction of the fortune i would be

what do you think of that now..hmm? any hints as to why this may interest me, and many other people out there...hmmm? think about shit before you just write some dumbfuckass remark about how cool you are and about how you'd go get yourself 1/10 of a gram and be on the nod for a week, get off me. stick to H if thats what you do, i don't care and i dont have anything against it, but don't troll a perfectly helpful and interesting thread cuz you're "too cool for anything but heroin..." even though the quality of shit you get probably comes no where near the quality of a properly filtered M-eslon shot.....but hey, you don't know what your missing until you've tried it right? and hye, if you're getting great stuff, great, i'm happy for you, but i bet you spend more than $50 a month, don't ya? i don't even care if you don't, to be honest, this is something that interests me and many other ppl, so don't troll it up



on another note, i wanted to put this thread up there again....any ideas anyone to make this work better/easier?

i have tried it and it worked, it was a whole lot of work though, and honestly, the end product was definetly cloudier than when i do up my own method and just filter real well. anyway, i dunno, the method i use is to heat up the meslon in 1ml of water, once it just starts to boil take away heat, crush meslon with back of rig until its one flat, white sheet on the bottom of the spoon, and keep crushing it until it starts reallyi coming apart and putting white particulates into the water, this is when it's breakng down more than the drugs, and you want to stop then. then pull it up onto the dry part of the spoon, so it can drip whats left into the puddle. then take a q-tip, dip it in water, and use a cleaned, but dull syringe (one that you aren't going to use on yourself, because if you push a nice sharp rig into qtips, you can dull them, this way you will have a nice sharp needle to use). suck out most of the water out of the tip of this (the water is so that the qtip doesn't just soak up all the solution, but you don't want it dripping with water when you put it in either), then put your dull (sucking) rig into this qtip, put the cotton part, with rig inserted, into the solution, once wetted slowly draw up. once it starts sucking some air bubbles, immediatly pull it out of the solution; at this point the cotton is saturated with wax/shit. poke the needle tip around a few different places and suck out everything, make sure you get ALL the liquod out of the tip. you *can* do a small wash on each tip, but honestly, i don't think much is left as i've tasted it before and it IS bitter, but not strongly so, and the taste doesn't last long. anwyays, once that happens, and you've sucked that tip dry, there's sure to be more soluation still left.....do the same thing again with theother side of the qtip. make sure that you use 3 needles for all of this, however. you have one (doesn't matter at all what condition this one is in, just make sure its yours and that its clean, but can be dull as anything) for JUST sucking the excess water out of the qtip before putting it in the solution, you have one for JUST sucking the solution THROUGH the qtip and out of the spoon, then you have the final one (this one's the sharp/new one, personally i use my rigs a few times over, but i am very careful with the tips, and i make sure to clean em pretty good too after each use, but at the very least make sure this one is sharp enough to go into your body VERY easily and with no pain, usually you can't use one more than a few times before it gets too dull to do a good job) and this one is the one that you inject with. after you've gotten all the solution out of the spoon, and have done all the washes you want to do (i do enough washes with enouhg water to fill up the rig RIGHT to the top (100 units) because this garuntee's i've taken the MOST amount of my drug out of the spoon. only doing one extraction leaves A LOT of morphine in there, and the rig (when i do it) is only about half full, so there's definetly room for one or two washes, and these increase the strength of the shot BY A LOT. anyways, you then back-load this sharp rig (take the plunger out, squirt in the shot from the back, then put the plunger in, making sure the tip of the needle is hovering over a CLEAN spoon ready to catch all the drops from putting the punger in) and then once you've gotten lots of the air out, make sure you suck back any of the solution that dripped out the tip when you were putting plunger in so you don't waste ANYTHING. waste not, want not.

anyways, once this is done, sit back, shoot, and enjoy. any comments/questions on this technique? when i'm done, i have a liquid that is VERY clear, i'd say almost 100% clear. considering that there IS the plastic barrel, the liquid looks about 90-98% clear...no floaties or particles in it, the only thing making it look not like water is there is *SOME* super minute tint to it, almost yellow but SO VERY faint you can HARDLY see it; it very well might be a reflection from something behind. anyways, it seems to be very clear, very pure, and very potent. when i do it this way, as copmared to anohter way which leaves a LOT more shit in the shot.....there is no difference in strength, thus i assume that there is HARDLY ANYTHING lost in this procedure. *SOME* must be, as nothing is 100% but it seems to be VERY efficient.

thanks for reading, and please, don't troll good threads; it's hard enough to get a good discussion going sometimes, there's no need to shit on somebody's thread; if you don't like whats being said, or dont agree, or even just have a different opinion.....please don't say anything relating to this. if you are gonna be a dick just dont say anything; if you can be constrctive, you're very welcome to post and thank you

thanks all

 

[pokin' canadian]

[EDIT- You don't need to make a separate post about "SWIM"- just edit your original post]
-Pdx

 

[-Guido-]

If your getting quality heroin its definitly not a waste compared to morphine. Diacetylmorphine is more effective at crossing the blood-brain barrier than morphine. You can get high with less compared to morphine.

Im curious though about shooting pills. I was always under the belief that it was something you should not do, escpecially pills composed of wax. But I see you and many others on this site have successfully done so and lived to tell about it and to do it again. Have any of you suffered any ill health effects?

 

[Flexistentialist]

The effects of shooting poorly filtered pills will often take a long time to develop. If the particles in the pill don't cause vein damage, they can lodge around the heart valves. This can cause endocarditis which is often fatal.

Whatever fragments don't get stuck around the heart valves will end up in lung tissue. Over time, this can cause a range of complications including interstitial lung disease. Since injecting MS Contin became popular in Australia a few years ago, we're now seeing some people developing emphysaema. I've also had one person I work with lose half their right lung as a complication from injecting wax matrix pills.

Just because you don't drop dead immediately after injecting doesn't mean it's safe and you're in the clear.

 

[pokin' canadian]

way to bust out a rant pokin'

but if i were you ide hock the pills to whoever wanted that garbage and go get some dope as stated earlier. there you got your funding for a heroin habit all taken care of and a more euphoric high to boot

yea, thats a good idea, but the problem is that my daily dose of morphine could supply me with a MAXIMUM of about 70 bucks a day to buy heroin with, and i would need at LEAST i'd say 100 bucks, if not 120 per day. the other problems associated with this are the fact that i will no longer be getting pharm qual drugs, i'll be getting street heroin, i also will have to score every few days, and i will also have to find some way to punt these pills, which isn't as easy as it sounds. i'd end up hanging out downtown for at least a few hours every week, or a day a month, or whatever, but the best part about being on this morphine from a dr instead of me getting it off the street like i had in the past, is that now i can avoid all this street bullshit, and i never have to go there. sine i've been going to this dr, i haven't had to go to the street but once, and that was my own fault cuz i was early on my script. thats SO much nicer, and the lesser high and higher doseage from morphine, well, i can live with it.

about the fucking your body up part, to be honest, i very highly doubt this is nearly as bad as you tihnk. for people who are using improperly , yes, it is probably horrible. for the people who are filtering properly and using proper technique, however, i don't think there is much risk at all. you see, i have been doing it for quite a while, and to be honest, there's been no problems with viens or anything else. before when i used to do it, i didn't do NEARLY as well of a filtering job, and i had MAJOR trackmarks from everyday injections. given, i also did cocaine via iv for a while, and that, i will say, left way worse marks than any morphine i've ever done. i HAVE noticed that the worse i filter my shots, or the worse they end up looking (as in less transparent) the more mark gets left after the injection, however, sine i've developed my new technique for filtering these pills, i've gotten syringes full of almost 100% transparent liquid, with NO particulates that one can see, only a very slight opacity to the liquid, instead of total clarity. it is always a lot cleaner feeling, and i don't seem to lose hardly any drug, if anything it's become a lot MORE efficient in the past few months, as i've refined my technique. the only way i can think of doing it better is to do an actual extraction using a few seperate solvents and a bunch of chemistry equipment. this would also nessesitate me having access to a lot more room than i have, and also me not having people around sometimes that do not approve of this type of thing, there fore i have to keep it covert and cannot afford to have a bunch of lab equipment lying around

anyways, yea, thats that

if anyone really wants to know this technique, i can post it

its very similar, well, sort of similar (in principle anyways) to negrogesic's method, although i find it works honestly much better (no offense meant man, i just mean to say that i've had much better experience in getting nice clean, high yield shots using my method rather than his. anyways, if there is any interest i will make a seperate thread and post it, maybe it'll get stickied

 

[gruvytune]

contains the following inactive ingredients: colloidal silicon dioxide, hydroxypropyl

the ones here are 60mg ER's from Endo Labs:

contains the following inactive ingredients: colloidal silicon dioxide, hydroxypropyl methylcellulose, lactose monohydrate,
magnesium stearate, and stearic acid.

would this technique work given this preparation? there is no wax per say is there?

seems the methylcellulose is the matrix which i would assume would be a whole lot less messy than ms contin


want eventually to go to Diacetyl using AA. and then to the HCL for nasal use.

what would be the simplest prep?

 

[fastandbulbous]

stearic acid

That's effectively your wax. Any long chain hydrocarbon is going to behave like a wax matrix. The hydroxypropyl methylcellulose is the stuff that'll absorb water if it's too hot and produce something with viscosity approaching that of snot/mucous. Silicon dioxide is insoluble in water or organic solvennts and magnesium stearate is what makes the soln frothy (it's effectively a form of soap - athough it's normally the Na or K salt)

 

[gruvytune]

thanks. pretty clear.

so when the toluene is added, wont the methylcellulose stay behind with the morp sulfate?


will mineral spirits dissolve morphine sulfate? curious if similar to toluene since can get that at home depot.