S-adenosyl-L-methionine (SAMe) and MDMA?

[indigoaura]

Anyone have any experience with mixing S-adenosyl-L-methionine and MDMA?

I have been using S-adenosyl-L-methionine as a supplement to support wellbeing etc. I take 200 mg at night before bed.

Curious as to whether I should stop taking the S-adenosyl-L-methionine prior to MDMA use, and if so, how many nights prior to MDMA use should I stop taking the SAMe?

Or, does it work to pre-load with it?

Any direct experience or theories would be appreciated. Thanks!

 

[simstim]

I can't believe you take SAMe at bedtime. I'm not usually a manic person without amphetamines or cocaine in me, but SAMe makes me start acting stereotypically manic when dosed in the A.M.

 

[indigoaura]

I can't believe you take SAMe at bedtime. I'm not usually a manic person without amphetamines or cocaine in me, but SAMe makes me start acting stereotypically manic when dosed in the A.M.

I know, right? I did not expect that either. However, when I take it in the day it has an odd sort of spaced out effect. So, I decided to try it at night. It gives me more vivid dreams, but otherwise does not interfere in my sleep. Then, I wake up feeling more alert and refreshed. It works for me like that.