Rolling on Prozac

[Naughty Vampire God]

I just started taking Prozac, and I notice that every now and then I start rolling on it. It increases with music and yohimbe bark, and it's really an enjoyable experience.
I've heard of other people almost rolling on Zoloft, and it got me thinking.
I was wondering what kinds of advice people had on increasing this effect (since I've got a month's worth of P and nothing better to do).
Also, anybody care to venture an explanation of the phenomenon, and how common it is?
Thanks.
NVG

 

[BOGBUBBLE]

Well they work in a very similar way.... When did you notice these effects? how many times did you take prozac before you "rolled"? And what other drugs do you take regularly?
Theres alot of things that could cause this. I find the people who tell me they roll off a few zolofts are the same people who nod off on red rock opium....
Although i believe anything is possible, SSRIS take 2weeks to increase levels of serotonin.

 

[xxanxx]

Hmmmmm, I donno about Prozac, but I have flipped out off 25mg of zoloft. I didn't take it with anything else at all. It caused jaw clenching, shaking, hallucinations, sweating, morbid thoughts, and went on for about 36-48 hours. Any thoughts? I hadn't tripped for about a month and didn't do anything else at all.

 

[Ayrios]

You're sure it wasn't something else? Zoloft takes a while to start working and I really doubt 25mg would do anything... My mom has 50mg Zolofts which I think she takes multiple times a day. It's not recreational stuff.

 

[TDogge]

I just thought I should clear a few things up. SSRI's do not require two weeks to increase serotonin levels. This effect occurs as soon as the drug is sufficiently absorbed into the bloodstream (30-40 min). For an SSRI to be clinically effective, however, it must be used consistently for 2-3 weeks, suggesting that the cause of the medical condition "depression" is a little more complicated than just low serotonin levels. As far as "rolling" from zoloft is concerned...it is important to remember that a drug experience (or any experience for that matter) appears to us only as we perceive it, and not as it really occurs. Therefore, if you perceive that you are rolling, then I guess you are. The neurochemical basis for this phenomenon is certainly not simple, but keep in mind that SSRI's do (as someone mentioned) act in a matter similar to that of MDMA in that they block the serotonin reuptake transporter. It's really not that simple, though, and I'm too tired to explain myself....

 

[fairnymph]

TDogge gave some good input...
It's not entirely uncommon for people to get slightly buzzed from an antidepressant when they first start taking it. However, any mildly recreational side effects of the AD usually subside after a week or so of taking the medication, if not sooner. So do not expect these effects to last for long.
This was my experience with Effexor and Edronax (reboxetine)...however sadly not the case with either Prozac or Remeron.

 

[day_for_night]

wrong forum. please read the posting guidelines at the top of the other drugs main page.
moved to ecstasy discussion.