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Stimulants Ritalin versus Vyvanse versus dextroamphetamine (dexedrine)?

Didn't respond well to vyvanse, at all.
Everyone is different. This is a point I find myself making frequently these days. Pharmacogenomics is a new-ish fascinating field of study in biochemistry, and it examines how we all vary according to our genetics and in terms of how we respond to various drugs. Your enzyme makeup can be radically different from someone elses, despite you both clearly being members of Homo Sapien Sapiens.

Felt horrible on it. Reminds me of regular amphetamines, and the after effects aren't as harsh as meth, but still suck.
I have a theory that among ppl who use stimulants, they usually fall into one of two—perhaps three—preference groups. You see, amphetamines are monoamine releasing agents, whilst cocaine, methylphenidate (Ritalin), cathinones and pyros are all monoamine reuptake inhibitors. So you've got one crowd who prefers the releasors, and another crowd who prefers the inhibitors. Arguably there is a third group who likes both, and if you like neither you aren't a stimulant user, obviously. But it seems to me like most stim users prefer one form over the other. People who like coke often respond well to methylphenidate. People who like amphetamine/methamphetamine often respond well to Adderall, Vyvanse, and Dexedrine.

Ritalin is the way to go for me personally, I just have to dose it twice daily.
Do you like cocaine, or not so much?

A totally absurd presumption you can t know, well you could if you would do a Sherlock on my posts,
took the time to broaden my response.
Sorry but your initial comments made it seem like you tried some of these stims once and maybe jumped to some conclusions that made it so you miss out on something useful to you if you only gave it another shot. Maybe not, but I wanted to try to keep options open for you, at least mentally. In retrospect and after reading over my words again a few days later, I realize I came across harsher than intended, and I owe you an apology for that. To that end, sorry for the mis-conveyed tone. However, I also want to say that this was not "a totally absurd presumption" even with a loose definition of the word, "absurd". There was clearly logic in my thinking based on what you said in that comment, not based on your oeuvre of past posts and comments.

Did during that unodelacosa fled, lost connexxion or what. @unodelacosa
Yeah I was busy this weekend. Lol, did you think you made such a good argument that I "fled"? Let's try not to flatter ourselves too much.

Proverbial, oh you mean what people call figure of speech.
Is English not your first language?

Using difficult words doesn t make things eassier, is that the aim.
I didn't know "proverbial" was a "difficult word". In my mind, I would think most English-speakers have heard of proverbs before—I mean, there's even a book in the Bible called Proverbs (not an endorsement of Christianity; just making a point that it's a popular book) and the adjective "proverbial", even if unfamiliar to them, wouldn't be challenging to figure out by context. I will admit though that I'm an American and, much like the British, we have a tendency to be anglocentric and I sometimes forget that for many ppl on Bluelight, English is a second or third language. It's not my intention to ostracize, antagonize, intimidate, belittle, or talk down to anyone with lofty pretentious language, and if that's how it came across to you at least know that was never the idea. I appreciate the feedback and impromptu, unsolicited constructive criticism though and while I won't apologize for my vocabulary, I will reflect on your feedback and consider it in the future when responding. But hey, in the meantime, at least you learned a new word, so it's not all bad, is it?

Hope not, much :heart6: you might need it on the way.
I feel like that heart graphic came from the Take On Me video from the 80s.

Hope not what? You hope that my aim was not to make things easier? That doesn't make sense. Either way, I recognize and appreciate your efforts to kill with kindness and to take a classy approach, but there's no argument here, really. Wouldn't you agree that for most drugs, using it only once isn't really enough to make a strong overall assessment on it. It's fine for a trip report or anecdote, but I think it should be encouraged to try a thing a few times in order to make a more thorough assessment of it, unless of course their reaction was negative enough to warrant avoiding it in the future out of concerns for safety. No one is requiring someone do a drug multiple times if they don't want to, I would just ask that person to at least provide that disclaimer before trashing it in a public review. Just my opinion. If you disagree, that's fine, too. It's not a very big deal to me, and though I appreciate the internet love / well wishes, and I reciprocate them, it's not necessary to smooth anything over or assuage my feelings, etc. One love back at you, my guy.

edit: my spirit animal is Turtle they slow on land but mean well 🐢.
They're fast in the ocean! Also, idk if you've ever had boiled snapping turtle, but it's very tender meat that tastes like steak (not chicken). My spirit animal is the octopus, the Agent 007 of the ocean; useless on land though, so don't take my words too seriously ;)
 
Everyone is different. This is a point !

Do you like cocaine, or not so much?

Sorry but your initial comments made it seem like you tried some of these stims once and maybe jumped to some conclusions that made it so you miss out on something useful to you if you only gave it another shot. Maybe not, but I wanted to try to keep options open for you, at least mentally. In retrospect and after reading over my words again a few days later, I realize I came across harsher than intended, and I owe you an apology for that. To that end, sorry for the mis-conveyed tone. However, I also want to say that this was not "a totally absurd presumption" even with a loose definition of the word, "absurd". There was clearly logic in my thinking based on what you said in that comment, not based on your oeuvre of past posts and comments.
That distinction you made Coke/ MPH people vs Amphetamine is concerning me spot on.
Amphetamine person, its just i am spoiled as i have, one of the few that use the route as i.
Free dextro-Amphetamine prescribed, and all the subtitutions mostly make em weirder 2-FA came close.
Wonder bout dextro-2-FA, how would that compare ?

I like harsh, don t bother. Just straight to the point differences and flaws you can sort out later.
If you share the same opinion [open for conflict/ meaning willing to find mutual ground],
you can have a discussion be friends and still disagree in the end.


Yeah I was busy this weekend. Lol, did you think you made such a good argument that I "fled"? Let's try not to flatter ourselves too much.


Is English not your first language?
No, and i was just being harsh/ raw. Or sarcasticly joking, but not ment to breach the peace.

But ment the warning bout 3-FA someone once posted on Bluelight.
A knowledgeable member or mod. Might be disproven by now, but had something to do with enlarged heart valves.
I didn't know "proverbial" was a "difficult word". In my mind, I would think most English-speakers have heard of proverbs before—I mean, there's even a book in the Bible called Proverbs (not an endorsement of Christianity; just making a point that it's a popular book) and the adjective "proverbial", even if unfamiliar to them, wouldn't be challenging to figure out by context. I will admit though that I'm an American and, much like the British, we have a tendency to be anglocentric and I sometimes forget that for many ppl on Bluelight, English is a second or third language. It's not my intention to ostracize, antagonize, intimidate, belittle, or talk down to anyone with lofty pretentious language, and if that's how it came across to you at least know that was never the idea. I appreciate the feedback and impromptu, unsolicited constructive criticism though and while I won't apologize for my vocabulary, I will reflect on your feedback and consider it in the future when responding. But hey, in the meantime, at least you learned a new word, so it's not all bad, is it?
Yeah proverbial was, figure of speech is almost Dutch [figuratief gesproken].
Learning is key, if you d know much i abuse the translater.
Back and forwards, you say i am a addict. But as short term memory also is inflicted.

It calls for extra attention. For recall.
But Dutch, and seizures kinda influenced my languistic part of the brain, thats my theory.
I feel like that heart graphic came from the Take On Me video from the 80s.
Could, its my favorit heart emoticon, Black and some draw charateristics.

Rather forget that musical period, so i ll take your word for it.
Hope not what? You hope that my aim was not to make things easier? That doesn't make sense. Either way, I recognize and appreciate your efforts to kill with kindness and to take a classy approach, but there's no argument here, really. Wouldn't you agree that for most drugs, using it only once isn't really enough to make a strong overall assessment on it. It's fine for a trip report or anecdote, but I think it should be encouraged to try a thing a few times in order to make a more thorough assessment of it, unless of course their reaction was negative enough to warrant avoiding it in the future out of concerns for safety. No one is requiring someone do a drug multiple times if they don't want to, I would just ask that person to at least provide that disclaimer before trashing it in a public review. Just my opinion. If you disagree, that's fine, too. It's not a very big deal to me, and though I appreciate the internet love / well wishes, and I reciprocate them, it's not necessary to smooth anything over or assuage my feelings, etc. One love back at you, my guy.
What ment that you would use difficult words on purpose. Again harsh/ sarcasme,
as i had to look up the word to find it just means figuratively spoken. Can t keep my mouth shut 😐
Probably when you totally mastered english a kinda insulting overcming remark.

Not ment, and learned a new word.Forget all the time too. ☯️
They're fast in the ocean! Also, idk if you've ever had boiled snapping turtle, but it's very tender meat that tastes like steak (not chicken). My spirit animal is the octopus, the Agent 007 of the ocean; useless on land though, so don't take my words too seriously ;)
Agent 007, wasn t it Agent 327. The only Dutch known comic.

"Dutch secret agent who fights for "Righteousness and World Peace"; his looks are based on the character of Peter Gunn.
Often partnered with the junoesque Olga Lawina (an agent of the Swiss Secret Service)."
[he debuted in PEP a comic magazine for kids]

And Turtles too superfast in water, slow as snails on land. They have a shared handicap.
you could say, but both are bizar and Octopusses are supposed to be clever too.

https://en.wikipedia.org/wiki/Agent_327
 
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Found my mistery substance, 5-IT/ 5-API [aminopropane indole]
IAP was lack luster and 5-API/ IT to, but others raved about it, but it caused deaths too.

2-FA imo ⬆️ 2-FMA, functionally.
 
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Yes, I can totally see your point. Methylphenidate is extremely short acting…..why I have BIPHENTIN XR 60mg capsules

40% of dose is IR ….remaining 60% of doses is released 4h after, reaching onset/peak in about 6h ….so about 10h of coverage

I usually pulverize the XR beads into fine powder so it’s all IR as I require about 60mg IR of Ritalin to feel its therapeutic effects…lasting 3-4 hours. I’ve never experienced any negative sideffects from Ritalin what so ever….except profound Euphoria and robust mood-boosting properties

If I had to choose an effective combo it would be:

Adderall XR 20mg beads
Dexedrine 5mg IR taken as needed to keep the “Oumph” of dopaminergic stimulant properties
Pregabalin (Lyrica) 150mg X 2 daily or a single 300mg on a fasted state 1.5h c-max
Alprazolam (Xanax) 1mg - Anxiolytic Benzo with antidepressant properties
Diazepam (Valium) 10mg X 2-3 tablets - Anxiolytic Benzo with robust muscle relaxant properties
Methadone 100mg (opioid tolerant individual) preferably Oxy-IR 20mg X 4-6 tablets as needed
Phenibut 1,500mg - 3h onset / c-max - potent anxiolytic + dopaminergic properties
Ethanol / Gin 2.oz X 3-6 cocktails every hour or so

The perfect oral Speedball / Brompton Cocktail 🍸 (multiple variations)

For a tolerant individual…..start low and go slow. Know your tolerance. Don’t be afraid to call 911 if needed. Specify, NO police and NO fire department…..just an EMS bus with NO sirens, to monitor vitals such as BP/HR and ensure your safety is ensured. Don’t be shy or scared to call 911 if needed ….I’ve done it twice before

My fckn tax dollars at work, my safety is paramount…..know your limits and tolerance

Educate yourself about any DDI’s and be aware of your cardiovascular health / medical issues …especially with dopaminergic stimulants such as Adderall and Amphetamines in general. They all carry “black box warnings” and try having rescue meds on hand just in case….

Be safe and have fun :)
Can you iv biphentin?
 
Can you iv biphentin?
Probably not. IIRC, biphentin is time-release methylphenidate. Not certain of the time-release mechanism, but it could cause some problems with getting a clean water extraction of the methylphenidate. It probably serves a dual function in that regard – it both facilitates time-release and prevents certain routes of administration deemed "drug abuse" by the Big Pharma overlords.

What is it a capsule filled with little dots? I guess if one crushed them up, put the resulting powder in a couple coffee filters and poured water slowly through it, if the water that comes through the filter looks relatively clear, then it might be ok after evaporating some of the water. Otherwise if the water is cloudy, might not be wise to inject that. Matter of fact, why risk that shit? It's just methylphenidate. There are far better stims. Don't waste a roll of the dice with this monkey garbage, honestly. Just my $0.02, but I outlined what I see as the safest procedure if you're gonna do it anyway, IMHO. Note please that I'm not a doctor and this is not medical advice. Good luck either way!
 
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Whether you're on phenidates or amphetamines tolerance will become an issue eventually if you're taking it every day. A week off is usually enough to get your tolerance near enough back to baseline.
Not ime, been on same dose 35 mg / day. Take less 25 mg mostly.

Never raised my dose. Never noticed any change between my first,
and this morning last dose. They are both at best barely noticeable,
steady for 20 years. Never lost effectiveness,
but take me of and doc s get crazy.

Like that the most:) as they take me of not me.
 
No that exactly how BIPHENTIN works….formulated for Biphasic release, hence the name

Methylphenidate takes 1h to reach effects, lasts for 3-4hours ……by the time you took your second 20mg tablet the effects from the previous dose would be ending

I’ve been taking for 10 years and 240lbs 6’ …..so 60mg IR at once is my dose

Someone else, 10mg would suffice ….a single 20mg tablet is adequate to enduce euphoric effects for a new user, easily.

Do you ever take 60 mg IR twice a day?
 
I've probably had Methylphenidate IR 100mg - 150mg spaced through the day.....an oral 50mg IR in morning with Methadone 100mg.....and another 100mg of Methylphenidate IR pulverize powder via insufflation, few fat lines before each new Gin 2.oz cocktail heading outside for a Belmont cigarette on the patio lol....my ritual kinda

Often Pregabalin 300mg + Diazepam 30mg + Alprazolam 1mg to compliment the Opioid & Dopaminergic stimulant....my classic hybrid oral Brompton Cocktail 🍸
 
Everyone is different. This is a point I find myself making frequently these days. Pharmacogenomics is a new-ish fascinating field of study in biochemistry, and it examines how we all vary according to our genetics and in terms of how we respond to various drugs. Your enzyme makeup can be radically different from someone elses, despite you both clearly being members of Homo Sapien Sapiens.


I have a theory that among ppl who use stimulants, they usually fall into one of two—perhaps three—preference groups. You see, amphetamines are monoamine releasing agents, whilst cocaine, methylphenidate (Ritalin), cathinones and pyros are all monoamine reuptake inhibitors. So you've got one crowd who prefers the releasors, and another crowd who prefers the inhibitors. Arguably there is a third group who likes both, and if you like neither you aren't a stimulant user, obviously. But it seems to me like most stim users prefer one form over the other. People who like coke often respond well to methylphenidate. People who like amphetamine/methamphetamine often respond well to Adderall, Vyvanse, and Dexedrine.
Dexedrine is ime just functional, on Racemic i am wired.
Methylphenidate is pure torture worse then Cocaine,
hate em both though. And all Phenidates inc MDPV.
Btw i have for sure ADD/ maybe Autistic features.

Cathinone, the fresh twigs i loved.
Adored and worshipped,
best stim for a sloppy social high.

And bk-MDMA ime is better then MDMA.

My theory is that Cathinone s are a category on their own.

Also react bad too Tryptamine s, Phenethylamine s
[psychedeluc ones except 2C-T2, hopefully Mescaline too].
But not Lysergics, Do i fall in a sub-category ?
 
Dexedrine is ime just functional,
Same for me. That's why it's useful for productivity.

Methylphenidate is pure torture worse then Cocaine, hate em both though.
I don't like coke or ritalin, either. Once in a blue moon I'll remind myself why I feel this way by doing a line and regretting it, lol.

And all Phenidates inc MDPV.
MDPV is not a phenidate drug. It's a pyrovalerone derivative and as such is classified as a substituted cathinone. The phenidates are all Ritalin-class drugs, if you will, and have a different structure & scaffolding.

Btw i have for sure ADD/ maybe Autistic features.
IIRC, the CDC says ~15.5 mil U.S. adults have been diagnosed wi/ADHD (includes Attention Deficit Disorder (ADD) too). In children, ~7 mil have been diagnosed w/ADHD.

Cathinone, the fresh twigs i loved.
You're talking about "Khat", Catha edulis. I've had it. It's a shame bc—due to global prohibition—it's a cash crop for farmers willing to be illicit exporters. The money is a lot better than w/vegetables—a huge incentive to grow khat instead of much-needed food. It's causing a crisis in Yemen. C. edulis is a thirsty plant that requires precious water resources that Yemen is already struggling with. Growing Khat exacerbates the issue while citizens are undernourished, starving, and sometimes strung-out. There's a similar sitch in south east Asia vis-à-vis meth production & use, but it's not as bad as Yemen where Khat is ~30% of their economy.

And bk-MDMA ime is better then MDMA.
I prefer MDA to either one.

My theory is that Cathinone s are a category on their own.
They are! There is a huge number of them, too. They fit within the broader category of phenethylamines. Consider: amphetamine is a word constructed from the term Alpha-Methyl-PHenyl-EThyl-AMINE ☞ "amphetamine". There are two spots next to the nitrogen on any phenethylamine, the alpha- and the beta-position. Placement of a methyl group (CH₃) at the alpha position designates that the phenethylamine in question is alpha methylated, or i.e. an amphetamine. Placement of that same methyl group at alpha and a double-bonded oxygen atom at beta determines that the phenethylamine is a cathinone. Similar structure and qualitative profile.

But not Lysergics, Do i fall in a sub-category ?
So you do or your don't like lysergamides?
 
Same for me. That's why it's useful for productivity.


I don't like coke or ritalin, either. Once in a blue moon I'll remind myself why I feel this way by doing a line and regretting it, lol.


MDPV is not a phenidate drug. It's a pyrovalerone derivative and as such is classified as a substituted cathinone. The phenidates are all Ritalin-class drugs, if you will, and have a different structure & scaffolding.

You're talking about "Khat", Catha edulis. I've had it. It's a shame bc—due to global prohibition—it's a cash crop for farmers willing to be illicit exporters. The money is a lot better than w/vegetables—a huge incentive to grow khat instead of much-needed food. It's causing a crisis in Yemen. C. edulis is a thirsty plant that requires precious water resources that Yemen is already struggling with. Growing Khat exacerbates the issue while citizens are undernourished, starving, and sometimes strung-out. There's a similar sitch in south east Asia vis-à-vis meth production & use, but it's not as bad as Yemen where Khat is ~30% of their economy.


I prefer MDA to either one.



So you do or your don't like lysergamides?
Most substituted Cathinones i don like, only Catha Edulis and bk-MDMA.
MDPV was so glorified i thought it was weird it felt like shit, 2 separate sources.
4-MMC i skipped as i knew i d like it.

Love Lysergics especially the dissapeared ALD-52,
actually the only psychedelics that feel right, OK and 2C-T2.

Heard about that water Qat / Food problem,
maybe for the best its made illegal here a long time ago.
 
I've probably had Methylphenidate IR 100mg - 150mg spaced through the day.....an oral 50mg IR in morning with Methadone 100mg.....and another 100mg of Methylphenidate IR pulverize powder via insufflation, few fat lines before each new Gin 2.oz cocktail heading outside for a Belmont cigarette on the patio lol....my ritual kinda

Often Pregabalin 300mg + Diazepam 30mg + Alprazolam 1mg to compliment the Opioid & Dopaminergic stimulant....my classic hybrid oral Brompton Cocktail 🍸

Did you mention it's better to take ritalin with or without food?

I've found it's necessary to use a small supplemental evening dose, simply to prevent an excessive crash too early, causing harsh insomnia that night.

I found the same thing on strattera.
 
See, I have the opposite philosophy. I think it's overreach for the govt. to say what plants we can and cannot have. It's our planet, too, you know? You see the outlandish pay from the blackmarket is precisely because of prohibition laws driving up the price artificially. If it were legalized everywhere, there wouldn't be a blackmarket for it and people could openly get the help they need when they need it to quit without fearing criminal prosecution. The world would be a better place if we ended prohibition after redirecting the money we spend on law enforcement of drug laws into recovery clinics and educating the public on the dangers of certain substances.
 
I tried a 50 mg dose this morning.

Too much, very panicky/jittery.

40 mg was fine.

Somewhere between 20 and 40 morning, then a top up of 20 in the evening may be the correct dose in my case.

But fuck 50 mg. When it went too high, it lost its pleasurable alert effect and just felt horrible.
 
See, I have the opposite philosophy. I think it's overreach for the govt. to say what plants we can and cannot have. It's our planet, too, you know? You see the outlandish pay from the blackmarket is precisely because of prohibition laws driving up the price artificially. If it were legalized everywhere, there wouldn't be a blackmarket for it and people could openly get the help they need when they need it to quit without fearing criminal prosecution. The world would be a better place if we ended prohibition after redirecting the money we spend on law enforcement of drug laws into recovery clinics and educating the public on the dangers of certain substances.
I agree.....BUT often think....if people had unlimited legal access to Diacetylmorphine (Heroin) / Methamphetamine (Desoxyn) / Cocaine base / Xanax, Valium, etc.......eventually serious pandemic medical costs and deaths, etc would quickly arise

Post WWII in Japan....Philipon (d-Desoxyephedrine/ Methamphetamine) flooded the civilian market from military stockpiles for munition workers, factory labour workers, combat soldiers etc.......so the entire country of Japan had MASSIVE amounts of branded tablets of pure d-Methamphetamine.....which, soon turned into a cluster f@ck for the Govt & health car system.

B.C. Canada has opioid pandemic from illicit Fentanyl from China......so bad so many OD deaths that the Govt has safe supply program giving free Dilaudid (Hydromorphone) 8mg tablets and injectable Hydromorphone & Diacetylmorphine (Heroin) 100% pure safe pharmaceutical grade medication.....not tainted illicit Fentanyl laced gear killing thousands

So ya......small to moderate therapeutic doses of controlled substances OTC seems great.......but there's a reason they're controlled substances

Inhaling massive clouds of freebase Cocaine 7 times a day will quickly transform that individual to a walking zombie

Injectable vials of 30mg Methedrine (d-Methamphetamine) would be like an atomic bomb of dopaminergic euphoric pleasure ....and you'd be using DAILY without a doubt ......$10 OTC at your local pharmacy, no script required ....just 5 glass ampoules of Methedrine and a bag of 1cc 30 gauge insulin syringes are you're goof for the week. Or half a week lol

But for ME personally......I'd have a basement vault with every CII substance in massive quantities suitable for long term storage in cold dard dry vault ......for personal use as needed lol
 
if people had unlimited legal access to Diacetylmorphine (Heroin) / Methamphetamine (Desoxyn) / Cocaine base / Xanax, Valium, etc.......eventually serious pandemic medical costs and deaths, etc would quickly arise
Not if the public were educated to the dangers and we took the money we spend on law enforcement vice squads, drug task forces, and the DEA, and instead we spent it on addiction recovery clinics, counseling, psychiatric treatment and meds, truthful PSAs, and we offered clean, safe, affordable drugs whilst ending prohibition it would absolutely work.

It's like drinking – most of the adult world can handle alcohol just fine. When we outlawed it during alcohol prohibition, people did not stop drinking. It only made matters worse. People went to speakeasies and were falling down in the streets drunk. People got methanol poisoning and gangsters like Al Capone were able to make a fortune and amass power. Even staunch prohibitionists from the temperance movement, like the Rockefellers, did a 180° after 12 years of failed prohibition. Prohibition is stupid. It does not work and only makes matters worse and more complicated while providing lucrative opportunities for real criminals

Look, some people in society are always going to have substance abuse disorder. Neither it nor substances are going away, and the move to bring drug stats down is not by criminalizing every day users. Yes, if done incorrectly, it will fail; and that's why we have to do it correctly the first time.

Post WWII in Japan....Philipon (d-Desoxyephedrine/ Methamphetamine) flooded the civilian market from military stockpiles for munition workers, factory labour workers, combat soldiers etc.......so the entire country of Japan had MASSIVE amounts of branded tablets of pure d-Methamphetamine.....which, soon turned into a cluster f@ck for the Govt & health car system.
Post WWII Japan isn't the best period to overanalyze and critique Nippon. They were going through some shit culturally at that time.

B.C. Canada has opioid pandemic from illicit Fentanyl from China......so bad so many OD deaths that the Govt has safe supply program giving free Dilaudid (Hydromorphone) 8mg tablets and injectable Hydromorphone & Diacetylmorphine (Heroin) 100% pure safe pharmaceutical grade medication.....not tainted illicit Fentanyl laced gear killing thousands
Right, Canada's approach if one of understanding and compassion. The US just locks everyone up. Do you know the "Prison Song" by System of a Down?



So ya......small to moderate therapeutic doses of controlled substances OTC seems great.......but there's a reason they're controlled substances
Yes, corporate lobby interests, racism, the 13th amendment's exception to slavery abolition for prisoners and cartel bribes.

Inhaling massive clouds of freebase Cocaine 7 times a day will quickly transform that individual to a walking zombie
"Walking zombie." ☜ As opposed to the non-mobile zombies? Lol, come on, that's scare tactics horseshit hyperbole, no offense, but it really is. If you abuse drugs in long marathon sessions while neglecting your health, nutrition, hygiene, responsibilities, and personal relationships, of course that's going to end badly. You're abusing drugs instead of using them responsibly.

Injectable vials of 30mg Methedrine (d-Methamphetamine)
Yeah I know what Methedrine is, or rather, was. It's been off the market for a long time; the only thing remaining is Desoxyn which hardly anyone will prescribe for fear of malpractice lawsuits. Meth is a demonized drug and people go overboard in warning about it. You never hear about the stories of people being responsible with it, because that's not a sensational headline. We only hear about the worst of the worst.

would be like an atomic bomb of dopaminergic euphoric pleasure
No it wouldn't. There are at least two whole generations that got fucked right outta that drug by abolitionist propaganda. They've become melodramatic, too convinced that meth is SUPER MEGA ULTRA BAD or something and they'll afraid of it of the drug, despite it's similarities to other prescription stimulants. There are only two kinds of people opposed to drugs – those who never used them, and those who sucked at using them. Everyone else had a great time and can control themselves.

....and you'd be using DAILY without a doubt ......$10 OTC at your local pharmacy, no script required ....just 5 glass ampoules of Methedrine and a bag of 1cc 30 gauge insulin syringes are you're goof for the week. Or half a week lol
Yeah no thanks, man, that route of administration is way too hardcore for yours truly. I'm not trying to have a stroke from mainlining a hit that's too big and unnecessary for anyone to take. I'm not into IV. And anyway, I've been using methamphetamine semi-regularly for ~two decades now. This, in addition to daily cannabis use, weekly psychedelic use, GHB/GBL, RC-stims- and disso-use from time-to-time, and all kinds of different multi-colored uppers, downers, screamers, laughers (to borrow a Hunter S. Thompson-ism). I've never OD'd, never been to rehab (and never needed to go), and I've never had legal problems stemming from my use.

I also generally don't drink except for when the social setting calls for it and then I impose a 2-drink limit on myself b/c I snowball otherwise. It's my least favorite drug. I'm also ~175 lbs. and my weight doesn't fluctuate from this. I have all my teeth still, steady income, a good relationship with my family, and I've been in a long-term relationship with my girlfriend for 11 years now (neither of us believe in legal marriage), and we're not having kids. I eat, sleep, and exercise regularly, and I take tolerance breaks from the drugs I use with any regularity. My GF is the same way and we have at least a dozen friends who are more or less the same way…

Check out the book, "Drug-Use For Grown-Ups" by Dr. Carl Hart

But for ME personally......I'd have a basement vault with every CII substance in massive quantities suitable for long term storage in cold dard dry vault ......for personal use as needed lol
Do you really think drug laws are the only thing preventing society from collapsing, despite the fact that psychotropic compounds have a much longer history of being legal and permitted, but society still made it to the 20th century okay. Then: Harry Anslinger went and fucked it up for everyone with the help of Dick Nixon, Ronald Reagan, and other pieces of shit in politics with similar views… Fuck the Reagans. Ollie North told that whole story, shady motherfuckers.

You don't reduce demand through criminalization; you reduce demand through education, tolerance and safety. It's 2025; time to put the drug war behind us.
 
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