Riddle Me This

[Ousley]

Anyone ever consider the fact that it is NOT the chemical ingested that gives one the feeling of being high. Those chemicals are already in your body. It is how the ingested substance causes ones brain to produce the substances that are already naturally ocurring?

 

[Rogue Robot]

We'll try this in Drug Culture.

DC mods, feel free to send back.

HOMELESS -> DC

 

[Bomboclat]

There was some documentary on drug use that had this question in it. Do you think that its the drug that gets you high, or is it the drug that can get you there and its your mind getting you high?

In fact, some either scientist or old acid head actually said this a while back (forgive me if the answer is obvious and I'm just not saying it, my memory on names is horrific!)
"Its not the drug that gets you high, the drug only gets you there, its your mind that does all the work." (or something along those lines)

Personally i think its the drug that gets you there, and your mind that keeps you high.
Good question man, also i love your name!
Monterey Purple ftw %)

 

[omgstfuplzttyl]

if its ALL in my head, ive sure wasted alot of money.

Its synergy, the drug acts with chemicals in the brain to make you "High". Im sure others will be alot more complex with their explanations, but thats what it comes down to.

 

[PureLife]

You tell me this now.

 

[DrGonzo899]

you ARE the drugs

 

[serotonin-system]

Anyone ever consider the fact that it is NOT the chemical ingested that gives one the feeling of being high. Those chemicals are already in your body. It is how the ingested substance causes ones brain to produce the substances that are already naturally ocurring?

This is true in some cases, ie for MDMA. It is the release of endogenous 5-HT by MDMA that is thought to account for most of the subjective effects, so here your theory stands true.

However, take drugs like LSD/opiates. Here you have a situation where the drug itself is acting as an agonist at specific receptor sites. Your body does not produce LSD or heroin/oxycodone etc itself.

Something I find interesting is how simply releasing a neurotransmitter/increasing its concentration (take MDMA/amphetamine/cocaine/SSRI's) induces euphoria/wellbeing. Considering the vast number of different 5-HT/DA receptors, it all just seems a bit....well easy. As if the 'break' on neurotransmitter release is responsible for witholding wellbeing. Why isn't it more complicated? We know that selective agonists at different 5-HT receptors have very different behavioural/psychological effects. Why isn't it this specificity extended to Mood?

SS

 

[guikidagain]

how is that a fucking riddle?

 

[safety]

When you take drugs you are introducing chemicals to your body. That's the plain truth.

Yes, if you didn't have a brain you wouldn't get high. But you wouldn't be able to think either.

Taking drugs introduces chemicals into your body. Which in turn produce an effect. They modify the existing framework.

 

[mr.dopeman]

its just a foreighn substance in the brain changing the normal way the brain functions causing cognitive effects known as the "high". theorthetically your brain could give you any high you wnated including some we dont even have drugs that will make it do yet. but the human brain is not hardwired to do that so it doesnt happen.

 

[ranunky]

it's the dopamine

 

[SyR1S]

yea dopamine is release in your brain form A LOT of drugs. The thing i find even more amazing is their is Cannabinoid receptors in our brain that the weed interacts with, now if weed is so bad why is are brain build for it?

 

[monstanoodle]

Evolution and pure coinsidence.